CD147 deficiency in T cells prevents thymic involution by inhibiting the EMT process in TECs in the presence of TGFβ

por Chen, Ruo, Wang, Ke, Feng, Zhuan, Zhang, Ming-Yang, Wu, Jiao, Geng, Jie-Jie, Chen, Zhi-Nan
Publicado 2020

Targeting CD147 for T to NK Lineage Reprogramming and Tumor Therapy

por Geng, Jie-Jie, Tang, Juan, Yang, Xiang-min, Chen, Ruo, Zhang, Yang, Zhang, Kui, Miao, Jin-Lin, Chen, Zhi-Nan, Zhu, Ping
Publicado 2017

CD98-induced CD147 signaling stabilizes the Foxp3 protein to maintain tissue homeostasis

por Geng, JieJie, Chen, Ruo, Yang, Feng-fan, Lin, Peng, Zhu, Yu-meng, Fu, Xianghui, Wang, Ke, Feng, Zhuan, Wu, Jiao, Zhang, Hai, Li, Qi-jing, Chen, Zhi-Nan, Zhu, Ping
Publicado 2021

A novel small-molecule compound targeting CD147 inhibits the motility and invasion of hepatocellular carcinoma cells

por Fu, Zhi-guang, Wang, Li, Cui, Hong-yong, Peng, Jian-long, Wang, Shi-jie, Geng, Jie-jie, Liu, Ji-de, Feng, Fei, Song, Fei, Li, Ling, Zhu, Ping, Jiang, Jian-li, Chen, Zhi-nan
Publicado 2016

CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells

por Wang, Ke, Chen, Wei, Zhang, Zheng, Deng, Yongqiang, Lian, Jian-Qi, Du, Peng, Wei, Ding, Zhang, Yang, Sun, Xiu-Xuan, Gong, Li, Yang, Xu, He, Lei, Zhang, Lei, Yang, Zhiwei, Geng, Jie-Jie, Chen, Ruo, Zhang, Hai, Wang, Bin, Zhu, Yu-Meng, Nan, Gang, Jiang, Jian-Li, Li, Ling, Wu, Jiao, Lin, Peng, Huang, Wan, Xie, Liangzhi, Zheng, Zhao-Hui, Zhang, Kui, Miao, Jin-Lin, Cui, Hong-Yong, Huang, Min, Zhang, Jun, Fu, Ling, Yang, Xiang-Min, Zhao, Zhongpeng, Sun, Shihui, Gu, Hongjing, Wang, Zhe, Wang, Chun-Fu, Lu, Yacheng, Liu, Ying-Ying, Wang, Qing-Yi, Bian, Huijie, Zhu, Ping, Chen, Zhi-Nan
Publicado 2020

Meplazumab in hospitalized adults with severe COVID-19 (DEFLECT): a multicenter, seamless phase 2/3, randomized, third-party double-blind clinical trial

por Bian, Huijie, Chen, Liang, Zheng, Zhao-Hui, Sun, Xiu-Xuan, Geng, Jie-Jie, Chen, Ruo, Wang, Ke, Yang, Xu, Chen, Shi-Rui, Chen, Si-Yu, Xie, Rong-Hua, Zhang, Kui, Miao, Jin-Lin, Jia, Jun-Feng, Tang, Hao, Liu, Shuang-Shuang, Shi, Hong-Wei, Yang, Yong, Chen, Xiao-Chun, Malhotra, Vinay, Nasir, Nosheen, Khanum, Iffat, Mahmood, Faisal, Hamid, Saeed, Stadnik, Claudio Marcel Berdun, Itinose, Kengi, de Oliveira, Caroline Cândida Carvalho, Dusilek, Cesar, Rivabem, Lucas, Cavalcante, Adilson Joaquim Westheimer, Lopes, Suzara Souto, Saporito, Wladmir Faustino, Fucci, Fábio José Concilio, Simon-Campos, Jesus Abraham, Wang, Ling, Liu, Lin-Na, Wang, Qing-Yi, Wei, Ding, Zhang, Zheng, Chen, Zhi-Nan, Zhu, Ping
Publicado 2023

Safety and efficacy of meplazumab in healthy volunteers and COVID-19 patients: a randomized phase 1 and an exploratory phase 2 trial

por Bian, Huijie, Zheng, Zhao-Hui, Wei, Ding, Wen, Aidong, Zhang, Zheng, Lian, Jian-Qi, Kang, Wen-Zhen, Hao, Chun-Qiu, Wang, Jing, Xie, Rong-Hua, Dong, Ke, Xia, Jie-Lai, Miao, Jin-Lin, Kang, Wen, Li, Guoquan, Zhang, Di, Zhang, Mingru, Sun, Xiu-Xuan, Ding, Likun, Zhang, Kui, Jia, Junfeng, Ding, Jin, Li, Zhiqin, Jia, Yanyan, Liu, Lin-Na, Zhang, Zhe, Gao, Zhao-Wei, Du, Hong, Yao, Na, Wang, Qing, Wang, Ke, Geng, Jie-Jie, Wang, Bin, Guo, Ting, Chen, Ruo, Zhu, Yu-Meng, Wang, Li-Juan, He, Qian, Yao, Rui-Rui, Shi, Ying, Yang, Xiang-Min, Zhou, Jian-Sheng, Ma, Yi-Nan, Wang, Ya-Tao, Liang, Xue, Huo, Fei, Wang, Zhe, Zhang, Yang, Yang, Xu, Zhang, Ye, Gao, Lu-Hua, Wang, Ling, Chen, Xiao-Chun, Tang, Hao, Liu, Shuang-Shuang, Wang, Qing-Yi, Chen, Zhi-Nan, Zhu, Ping
Publicado 2021