Targeting proteostasis and autophagy in SMARCB1-deficient malignancies: where next?

por Msaouel, Pavlos, Carugo, Alessandro, Genovese, Giannicola
Publicado 2019

Molecular hallmarks of renal medullary carcinoma: more to c-MYC than meets the eye

por Msaouel, Pavlos, Walker, Cheryl L., Genovese, Giannicola, Tannir, Nizar M.
Publicado 2020

Leukotrienes, a potential target for Covid-19

por Citron, Francesca, Perelli, Luigi, Deem, Angela K., Genovese, Giannicola, Viale, Andrea
Publicado 2020

KRAS-Dependency in Pancreatic Ductal Adenocarcinoma: Mechanisms of Escaping in Resistance to KRAS Inhibitors and Perspectives of Therapy

por Gurreri, Enrico, Genovese, Giannicola, Perelli, Luigi, Agostini, Antonio, Piro, Geny, Carbone, Carmine, Tortora, Giampaolo
Publicado 2023

Cancer Genetics and Therapeutic Opportunities in Urologic Practice

por Adashek, Jacob J., Leonard, Alex, Roszik, Jason, Menta, Arjun K., Genovese, Giannicola, Subbiah, Vivek, Msaouel, Pavlos
Publicado 2020

Renal Cell Carcinoma Unclassified with Medullary Phenotype in a Patient with Neurofibromatosis Type 2

por Sarkar, Sanila, Throckmorton, Whitney, Bingham, Racheal, Msaouel, Pavlos, Genovese, Giannicola, Slopis, John, Rao, Priya, Sadighi, Zsila, Herzog, Cynthia E.
Publicado 2023

Increased expression of CD133 and reduced dystroglycan expression are strong predictors of poor outcome in colon cancer patients

por Coco, Claudio, Zannoni, Gian Franco, Caredda, Emanuele, Sioletic, Stefano, Boninsegna, Alma, Migaldi, Mario, Rizzo, Gianluca, Bonetti, Luca Reggiani, Genovese, Giannicola, Stigliano, Egidio, Cittadini, Achille, Sgambato, Alessandro
Publicado 2012

Efficacy and Safety of Bevacizumab Plus Erlotinib in Patients with Renal Medullary Carcinoma

por Wiele, Andrew J., Surasi, Devaki Shilpa, Rao, Priya, Sircar, Kanishka, Su, Xiaoping, Bathala, Tharakeswara K., Shah, Amishi Y., Jonasch, Eric, Cataldo, Vince D., Genovese, Giannicola, Karam, Jose A., Wood, Christopher G., Tannir, Nizar M., Msaouel, Pavlos
Publicado 2021

Multi-site desmoplastic small round cell tumors are genetically related and immune-cold

por Wu, Chia-Chin, Beird, Hannah C., Lamhamedi-Cherradi, Salah-Eddine, Soeung, Melinda, Ingram, Davis, Truong, Danh D., Porter, Robert W., Krishnan, Sandhya, Little, Latasha, Gumbs, Curtis, Zhang, Jianhua, Titus, Mark, Genovese, Giannicola, Ludwig, Joseph A., Lazar, Alexander J., Hayes-Jordan, Andrea, Futreal, P. Andrew
Publicado 2022

Passenger Deletions Generate Therapeutic Vulnerabilities in Cancer

por Muller, Florian L., Colla, Simona, Aquilanti, Elisa, Manzo, Veronica, Genovese, Giannicola, Lee, Jaclyn, Eisenson, Dan, Narurkar, Rujuta, Deng, Pingna, Nezi, Luigi, Lee, Michelle, Hu, Baoli, Hu, Jian, Sahin, Ergun, Ong, Derrick, Fletcher-Sananikone, Eliot, Ho, Dennis, Kwong, Lawrence, Brennan, Cameron, Wang, Y. Alan, Chin, Lynda, DePinho, Ronald A.
Publicado 2012

Neddylation inhibition sensitises renal medullary carcinoma tumours to platinum chemotherapy

por Shapiro, Daniel D., Zacharias, Niki Millward, Tripathi, Durga N., Karki, Menuka, Bertocchio, Jean‐Philippe, Soeung, Melinda, He, Rong, Westerman, Mary E., Gao, Jianjun, Rao, Priya, Lam, Truong N. A., Jonasch, Eric, Perelli, Luigi, Cheng, Emily H., Carugo, Alessandro, Heffernan, Timothy P., Walker, Cheryl L., Genovese, Giannicola, Tannir, Nizar M., Karam, Jose A., Msaouel, Pavlos
Publicado 2023

Ether phospholipids are required for mitochondrial reactive oxygen species homeostasis

por Chen, Ziheng, Ho, I-Lin, Soeung, Melinda, Yen, Er-Yen, Liu, Jintan, Yan, Liang, Rose, Johnathon L., Srinivasan, Sanjana, Jiang, Shan, Edward Chang, Q., Feng, Ningping, Gay, Jason P., Wang, Qi, Wang, Jing, Lorenzi, Philip L., Veillon, Lucas J., Wei, Bo, Weinstein, John N., Deem, Angela K., Gao, Sisi, Genovese, Giannicola, Viale, Andrea, Yao, Wantong, Lyssiotis, Costas A., Marszalek, Joseph R., Draetta, Giulio F., Ying, Haoqiang
Publicado 2023

SMARCB1 regulates the hypoxic stress response in sickle cell trait

por Soeung, Melinda, Perelli, Luigi, Chen, Ziheng, Dondossola, Eleonora, Ho, I-Lin, Carbone, Federica, Zhang, Li, Khan, Hania, Le, Courtney N., Zhu, Cihui, Peoples, Michael D., Feng, Ningping, Jiang, Shan, Zacharias, Niki Millward, Minelli, Rosalba, Shapiro, Daniel D., Deem, Angela K., Gao, Sisi, Cheng, Emily H., Lucchetti, Donatella, Walker, Cheryl L., Carugo, Alessandro, Giuliani, Virginia, Heffernan, Timothy P., Viale, Andrea, Tannir, Nizar M., Draetta, Giulio F., Msaouel, Pavlos, Genovese, Giannicola
Publicado 2023

Association of High-Intensity Exercise with Renal Medullary Carcinoma in Individuals with Sickle Cell Trait: Clinical Observations and Experimental Animal Studies

por Shapiro, Daniel D., Soeung, Melinda, Perelli, Luigi, Dondossola, Eleonora, Surasi, Devaki Shilpa, Tripathi, Durga N., Bertocchio, Jean-Philippe, Carbone, Federica, Starbuck, Michael W., Van Alstine, Michael L., Rao, Priya, Katz, Matthew H. G., Parker, Nathan H., Shah, Amishi Y., Carugo, Alessandro, Heffernan, Timothy P., Schadler, Keri L., Logothetis, Christopher, Walker, Cheryl L., Wood, Christopher G., Karam, Jose A., Draetta, Giulio F., Tannir, Nizar M., Genovese, Giannicola, Msaouel, Pavlos
Publicado 2021

Medium-Chain Acyl-CoA Dehydrogenase Protects Mitochondria from Lipid Peroxidation in Glioblastoma

por Puca, Francesca, Yu, Fei, Bartolacci, Caterina, Pettazzoni, Piergiorgio, Carugo, Alessandro, Huang-Hobbs, Emmet, Liu, Jintan, Zanca, Ciro, Carbone, Federica, Del Poggetto, Edoardo, Gumin, Joy, Dasgupta, Pushan, Seth, Sahil, Srinivasan, Sanjana, Lang, Frederick F., Sulman, Erik P., Lorenzi, Philip L., Tan, Lin, Shan, Mengrou, Tolstyka, Zachary P., Kachman, Maureen, Zhang, Li, Gao, Sisi, Deem, Angela K., Genovese, Giannicola, Scaglioni, Pier Paolo, Lyssiotis, Costas A., Viale, Andrea, Draetta, Giulio F.
Publicado 2021

In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma

por Kaushik, Akash K., Tarangelo, Amy, Boroughs, Lindsey K., Ragavan, Mukundan, Zhang, Yuanyuan, Wu, Cheng-Yang, Li, Xiangyi, Ahumada, Kristen, Chiang, Jui-Chung, Tcheuyap, Vanina T., Saatchi, Faeze, Do, Quyen N., Yong, Cissy, Rosales, Tracy, Stevens, Christina, Rao, Aparna D., Faubert, Brandon, Pachnis, Panayotis, Zacharias, Lauren G., Vu, Hieu, Cai, Feng, Mathews, Thomas P., Genovese, Giannicola, Slusher, Barbara S., Kapur, Payal, Sun, Xiankai, Merritt, Matthew, Brugarolas, James, DeBerardinis, Ralph J.
Publicado 2022

PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma

por Giuliani, Virginia, Miller, Meredith A., Liu, Chiu-Yi, Hartono, Stella R., Class, Caleb A., Bristow, Christopher A., Suzuki, Erika, Sanz, Lionel A., Gao, Guang, Gay, Jason P., Feng, Ningping, Rose, Johnathon L., Tomihara, Hideo, Daniele, Joseph R., Peoples, Michael D., Bardenhagen, Jennifer P., Geck Do, Mary K., Chang, Qing E., Vangamudi, Bhavatarini, Vellano, Christopher, Ying, Haoqiang, Deem, Angela K., Do, Kim-Anh, Genovese, Giannicola, Marszalek, Joseph R., Kovacs, Jeffrey J., Kim, Michael, Fleming, Jason B., Guccione, Ernesto, Viale, Andrea, Maitra, Anirban, Emilia Di Francesco, M., Yap, Timothy A., Jones, Philip, Draetta, Giulio, Carugo, Alessandro, Chedin, Frederic, Heffernan, Timothy P.
Publicado 2021

Interferon signaling promotes tolerance to chromosomal instability during metastatic evolution in renal cancer

por Perelli, Luigi, Carbone, Federica, Zhang, Li, Huang, Justin K., Le, Courtney, Khan, Hania, Citron, Francesca, Del Poggetto, Edoardo, Gutschner, Tony, Tomihara, Hideo, Soeung, Melinda, Minelli, Rosalba, Srinivasan, Sanjana, Peoples, Michael, Lam, Truong Nguyen Anh, Lundgren, Sebastian, Xia, Ruohan, Zhu, Cihui, Mohamed, Alaa M. T., Zhang, Jianhua, Sircar, Kanishka, Sgambato, Alessandro, Gao, JianJun, Jonasch, Eric, Draetta, Giulio F., Futreal, Andrew, Bakouny, Ziad, Van Allen, Eliezer M., Choueiri, Toni, Signoretti, Sabina, Msaouel, Pavlos, Litchfield, Kevin, Turajlic, Samra, Wang, Linghua, Chen, Ying Bei, Di Natale, Renzo G., Hakimi, A. Ari, Giuliani, Virginia, Heffernan, Timothy P., Viale, Andrea, Bristow, Christopher A., Tannir, Nizar M., Carugo, Alessandro, Genovese, Giannicola
Publicado 2023

Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma

por Bakouny, Ziad, Braun, David A., Shukla, Sachet A., Pan, Wenting, Gao, Xin, Hou, Yue, Flaifel, Abdallah, Tang, Stephen, Bosma-Moody, Alice, He, Meng Xiao, Vokes, Natalie, Nyman, Jackson, Xie, Wanling, Nassar, Amin H., Abou Alaiwi, Sarah, Flippot, Ronan, Bouchard, Gabrielle, Steinharter, John A., Nuzzo, Pier Vitale, Ficial, Miriam, Sant’Angelo, Miriam, Forman, Juliet, Berchuck, Jacob E., Dudani, Shaan, Bi, Kevin, Park, Jihye, Camp, Sabrina, Sticco-Ivins, Maura, Hirsch, Laure, Baca, Sylvan C., Wind-Rotolo, Megan, Ross-Macdonald, Petra, Sun, Maxine, Lee, Gwo-Shu Mary, Chang, Steven L., Wei, Xiao X., McGregor, Bradley A., Harshman, Lauren C., Genovese, Giannicola, Ellis, Leigh, Pomerantz, Mark, Hirsch, Michelle S., Freedman, Matthew L., Atkins, Michael B., Wu, Catherine J., Ho, Thai H., Linehan, W. Marston, McDermott, David F., Heng, Daniel Y. C., Viswanathan, Srinivas R., Signoretti, Sabina, Van Allen, Eliezer M., Choueiri, Toni K.
Publicado 2021