Novel antisense therapy targeting microRNA-132 in patients with heart failure: results of a first-in-human Phase 1b randomized, double-blind, placebo-controlled study

por Täubel, Jörg, Hauke, Wilfried, Rump, Steffen, Viereck, Janika, Batkai, Sandor, Poetzsch, Jenny, Rode, Laura, Weigt, Henning, Genschel, Celina, Lorch, Ulrike, Theek, Carmen, Levin, Arthur A, Bauersachs, Johann, Solomon, Scott D, Thum, Thomas
Publicado 2020

CDR132L improves systolic and diastolic function in a large animal model of chronic heart failure

por Batkai, Sandor, Genschel, Celina, Viereck, Janika, Rump, Steffen, Bär, Christian, Borchert, Tobias, Traxler, Denise, Riesenhuber, Martin, Spannbauer, Andreas, Lukovic, Dominika, Zlabinger, Katrin, Hašimbegović, Ena, Winkler, Johannes, Garamvölgyi, Rita, Neitzel, Sonja, Gyöngyösi, Mariann, Thum, Thomas
Publicado 2020

Hypoxia-induced long non-coding RNA Malat1 is dispensable for renal ischemia/reperfusion-injury

por Kölling, Malte, Genschel, Celina, Kaucsar, Tamas, Hübner, Anika, Rong, Song, Schmitt, Roland, Sörensen-Zender, Inga, Haddad, George, Kistler, Andreas, Seeger, Harald, Kielstein, Jan T., Fliser, Danilo, Haller, Hermann, Wüthrich, Rudolf, Zörnig, Martin, Thum, Thomas, Lorenzen, Johan
Publicado 2018

Long Noncoding RNA-Enriched Vesicles Secreted by Hypoxic Cardiomyocytes Drive Cardiac Fibrosis

por Kenneweg, Franziska, Bang, Claudia, Xiao, Ke, Boulanger, Chantal M., Loyer, Xavier, Mazlan, Stephane, Schroen, Blanche, Hermans-Beijnsberger, Steffie, Foinquinos, Ariana, Hirt, Marc N., Eschenhagen, Thomas, Funcke, Sandra, Stojanovic, Stevan, Genschel, Celina, Schimmel, Katharina, Just, Annette, Pfanne, Angelika, Scherf, Kristian, Dehmel, Susann, Raemon-Buettner, Stella M., Fiedler, Jan, Thum, Thomas
Publicado 2019

Preclinical development of a miR-132 inhibitor for heart failure treatment

por Foinquinos, Ariana, Batkai, Sandor, Genschel, Celina, Viereck, Janika, Rump, Steffen, Gyöngyösi, Mariann, Traxler, Denise, Riesenhuber, Martin, Spannbauer, Andreas, Lukovic, Dominika, Weber, Natalie, Zlabinger, Katrin, Hašimbegović, Ena, Winkler, Johannes, Fiedler, Jan, Dangwal, Seema, Fischer, Martin, Roche, Jeanne de la, Wojciechowski, Daniel, Kraft, Theresia, Garamvölgyi, Rita, Neitzel, Sonja, Chatterjee, Shambhabi, Yin, Xiaoke, Bär, Christian, Mayr, Manuel, Xiao, Ke, Thum, Thomas
Publicado 2020