Haptoglobin treatment prevents cell-free hemoglobin exacerbated mortality in experimental rat sepsis

por Schaer, Christian A., Jeger, Victor, Gentinetta, Thomas, Spahn, Donat R., Vallelian, Florence, Rudiger, Alain, Schaer, Dominik J.
Publicado 2021

Hemopexin as an Inhibitor of Hemolysis-Induced Complement Activation

por Poillerat, Victoria, Gentinetta, Thomas, Leon, Juliette, Wassmer, Andreas, Edler, Monika, Torset, Carine, Luo, Dandan, Tuffin, Gerald, Roumenina, Lubka T.
Publicado 2020

Cell-free oxidized hemoglobin drives reactive oxygen species production and pro-inflammation in an immature primary rat mixed glial cell culture

por Agyemang, Alex Adusei, Kvist, Suvi Vallius, Brinkman, Nathan, Gentinetta, Thomas, Illa, Miriam, Ortenlöf, Niklas, Holmqvist, Bo, Ley, David, Gram, Magnus
Publicado 2021

Heme-stress activated NRF2 skews fate trajectories of bone marrow cells from dendritic cells towards red pulp-like macrophages in hemolytic anemia

por Vallelian, Florence, Buzzi, Raphael M., Pfefferlé, Marc, Yalamanoglu, Ayla, Dubach, Irina L., Wassmer, Andreas, Gentinetta, Thomas, Hansen, Kerstin, Humar, Rok, Schulthess, Nadja, Schaer, Christian A., Schaer, Dominik J.
Publicado 2022

Characterization of Renal Injury and Inflammation in an Experimental Model of Intravascular Hemolysis

por Merle, Nicolas S., Grunenwald, Anne, Figueres, Marie-Lucile, Chauvet, Sophie, Daugan, Marie, Knockaert, Samantha, Robe-Rybkine, Tania, Noe, Remi, May, Olivia, Frimat, Marie, Brinkman, Nathan, Gentinetta, Thomas, Miescher, Sylvia, Houillier, Pascal, Legros, Veronique, Gonnet, Florence, Blanc-Brude, Olivier P., Rabant, Marion, Daniel, Regis, Dimitrov, Jordan D., Roumenina, Lubka T.
Publicado 2018

Plasma-Derived Hemopexin as a Candidate Therapeutic Agent for Acute Vaso-Occlusion in Sickle Cell Disease: Preclinical Evidence

por Gentinetta, Thomas, Belcher, John D., Brügger-Verdon, Valérie, Adam, Jacqueline, Ruthsatz, Tanja, Bain, Joseph, Schu, Daniel, Ventrici, Lisa, Edler, Monika, Lioe, Hadi, Patel, Kalpeshkumar, Chen, Chunsheng, Nguyen, Julia, Abdulla, Fuad, Zhang, Ping, Wassmer, Andreas, Jain, Meena, Mischnik, Marcel, Pelzing, Matthias, Martin, Kirstee, Davis, Roslyn, Didichenko, Svetlana, Schaub, Alexander, Brinkman, Nathan, Herzog, Eva, Zürcher, Adrian, Vercellotti, Gregory M., Kato, Gregory J., Höbarth, Gerald
Publicado 2022