Precision medicine in pediatric oncology

by Forrest, Suzanne J., Geoerger, Birgit, Janeway, Katherine A.
Published 2018

Relevance of Fusion Genes in Pediatric Cancers: Toward Precision Medicine

by Dupain, Célia, Harttrampf, Anne Catherine, Urbinati, Giorgia, Geoerger, Birgit, Massaad-Massade, Liliane
Published 2017

Insight into the interplay between mitochondria-regulated cell death and energetic metabolism in osteosarcoma

by Lai, Hong Toan, Naumova, Nataliia, Marchais, Antonin, Gaspar, Nathalie, Geoerger, Birgit, Brenner, Catherine
Published 2022

Histone deacetylase inhibitor panobinostat induces antitumor activity in epithelioid sarcoma and rhabdoid tumor by growth factor receptor modulation

by Harttrampf, Anne Catherine, da Costa, Maria Eugenia Marques, Renoult, Aline, Daudigeos-Dubus, Estelle, Geoerger, Birgit
Published 2021

Dabrafenib, alone or in combination with trametinib, in BRAF V600–mutated pediatric Langerhans cell histiocytosis

by Whitlock, James A., Geoerger, Birgit, Dunkel, Ira J., Roughton, Michael, Choi, Jeea, Osterloh, Lisa, Russo, Mark, Hargrave, Darren
Published 2023

A Perspective on Polo-Like Kinase-1 Inhibition for the Treatment of Rhabdomyosarcomas

by Gatz, Susanne A., Aladowicz, Ewa, Casanova, Michela, Chisholm, Julia C., Kearns, Pamela R., Fulda, Simone, Geoerger, Birgit, Schäfer, Beat W., Shipley, Janet M.
Published 2019

Efficacy and Safety of Trametinib Monotherapy or in Combination With Dabrafenib in Pediatric BRAF V600–Mutant Low-Grade Glioma

by Bouffet, Eric, Geoerger, Birgit, Moertel, Christopher, Whitlock, James A., Aerts, Isabelle, Hargrave, Darren, Osterloh, Lisa, Tan, Eugene, Choi, Jeea, Russo, Mark, Fox, Elizabeth
Published 2023

Profound and sustained response with next-generation ALK inhibitors in patients with relapsed or progressive ALK-positive anaplastic large cell lymphoma with central nervous system...

by Rigaud, Charlotte, Abbou, Samuel, Ducasso, Stéphane, Simonin, Mathieu, Le Mouel, Lou, Pereira, Victor, Gourdon, Stéphanie, Lambilliotte, Anne, Geoerger, Birgit, Minard-Colin, Véronique, Brugières, Laurence
Published 2022

Establishment and characterization of in vivo orthotopic bioluminescent xenograft models from human osteosarcoma cell lines in Swiss nude and NSG mice

by Marques da Costa, Maria Eugenia, Daudigeos‐Dubus, Estelle, Gomez‐Brouchet, Anne, Bawa, Olivia, Rouffiac, Valerie, Serra, Massimo, Scotlandi, Katia, Santos, Conceição, Geoerger, Birgit, Gaspar, Nathalie
Published 2018

In-Vitro and In-Vivo Establishment and Characterization of Bioluminescent Orthotopic Chemotherapy-Resistant Human Osteosarcoma Models in NSG Mice

by Marques da Costa, Maria Eugénia, Marchais, Antonin, Gomez-Brouchet, Anne, Job, Bastien, Assoun, Noémie, Daudigeos-Dubus, Estelle, Fromigué, Olivia, Santos, Conceição, Geoerger, Birgit, Gaspar, Nathalie
Published 2019

HGG-18. Long-term efficacy and safety of larotrectinib in paediatric patients with tropomyosin receptor kinase (TRK) fusion-positive primary central nervous system (CNS) tumours

by Nysom, Karsten, Doz, François, Geoerger, Birgit, Øra, Ingrid, Perreault, Sebastien, Norenberg, Ricarda, Fellous, Marc, De La Cuesta, Esther, Laetsch, Theodore W, van Tilburg, Cornelis M
Published 2022

Regorafenib: Antitumor Activity upon Mono and Combination Therapy in Preclinical Pediatric Malignancy Models

by Daudigeos-Dubus, Estelle, Le Dret, Ludivine, Lanvers-Kaminsky, Claudia, Bawa, Olivia, Opolon, Paule, Vievard, Albane, Villa, Irène, Pagès, Mélanie, Bosq, Jacques, Vassal, Gilles, Zopf, Dieter, Geoerger, Birgit
Published 2015

Rapid and highly sensitive approach for multiplexed somatic fusion detection

by Abbou, Samuel, Finstuen-Magro, Sarah, McDannell, Brigit, Feenstra, Michelle, Ward, Abigail, Shulman, David S., Geoerger, Birgit, Duplan, Joadly, Comeau, Hannah, Janeway, Katherine A., Klega, Kelly, Crompton, Brian D.
Published 2022

Bone Sarcomas: From Biology to Targeted Therapies

by Gaspar, Nathalie, Di Giannatale, Angela, Geoerger, Birgit, Redini, Françoise, Corradini, Nadège, Enz-Werle, Natacha, Tirode, Franck, Marec-Berard, Perrine, Gentet, Jean-Claude, Laurence, Valérie, Piperno-Neumann, Sophie, Oberlin, Odile, Brugieres, Laurence
Published 2012

A phase 1 study of oral ridaforolimus in pediatric patients with advanced solid tumors

by Pearson, Andrew D.J., Federico, Sara M., Aerts, Isabelle, Hargrave, Darren R., DuBois, Steven G., Iannone, Robert, Geschwindt, Ryan D., Wang, Ruixue, Haluska, Frank G., Trippett, Tanya M., Geoerger, Birgit
Published 2016

Multimodal immunogenomic biomarker analysis of tumors from pediatric patients enrolled to a phase 1-2 study of single-agent atezolizumab

by Nabbi, Arash, Danesh, Arnavaz, Espin-Garcia, Osvaldo, Pedersen, Stephanie, Wellum, Johanna, Fu, Lingyan Helen, Paulson, Joseph N., Geoerger, Birgit, Marshall, Lynley V., Trippett, Tanya, Rossato, Gianluca, Pugh, Trevor J., Hutchinson, Katherine E.
Published 2023

Regorafenib plus Vincristine and Irinotecan in Pediatric Patients with Recurrent/Refractory Solid Tumors: An Innovative Therapy for Children with Cancer Study

by Casanova, Michela, Bautista, Francisco, Campbell-Hewson, Quentin, Makin, Guy, Marshall, Lynley V., Verschuur, Arnauld C., Cañete Nieto, Adela, Corradini, Nadège, Ploeger, Bart A., Brennan, Barbara J., Mueller, Udo, Zebger-Gong, Hong, Chung, John W., Geoerger, Birgit
Published 2023

LGG-49. SAFETY AND EFFICACY OF TRAMETINIB (T) MONOTHERAPY AND DABRAFENIB + TRAMETINIB (D+T) COMBINATION THERAPY IN PEDIATRIC PATIENTS WITH BRAF V600-MUTANT LOW-GRADE GLIOMA (LGG)

by Bouffet, Eric, Whitlock, James A, Moertel, Christopher, Geoerger, Birgit, Aerts, Isabelle, Hargrave, Darren, Cohen, Kenneth J, Kilburn, Lindsay B, Upadhyaya, Santhosh A, Wetmore, Cynthia, Wright, Karen D, Choi, Jeea, Gasal, Eduard, Russo, Mark W, Fox, Elizabeth
Published 2020

Clinical and molecular analysis of smoothened inhibitors in Sonic Hedgehog medulloblastoma

by Pereira, Victor, Torrejon, Jacob, Kariyawasam, Dulanjalee, Berlanga, Pablo, Guerrini-Rousseau, Léa, Ayrault, Olivier, Varlet, Pascale, Tauziède-Espariat, Arnault, Puget, Stéphanie, Bolle, Stéphanie, Beccaria, Kevin, Blauwblomme, Thomas, Brugières, Laurence, Grill, Jacques, Geoerger, Birgit, Dufour, Christelle, Abbou, Samuel
Published 2021

Sequential genomic analysis using a multisample/multiplatform approach to better define rhabdomyosarcoma progression and relapse

by de Traux de Wardin, Henry, Dermawan, Josephine K., Merlin, Marie-Sophie, Wexler, Leonard H., Orbach, Daniel, Vanoli, Fabio, Schleiermacher, Gudrun, Geoerger, Birgit, Ballet, Stelly, Guillemot, Delphine, Frouin, Eléonore, Cyrille, Stacy, Delattre, Olivier, Pierron, Gaelle, Antonescu, Cristina R.
Published 2023