Biofilm formation by staphylococci and streptococci: structural, functional, and regulatory aspects and implications for pathogenesis

por Speziale, Pietro, Geoghegan, Joan A.
Publicado 2015

The A domain of clonal complex 1-type fibronectin binding protein B promotes adherence and biofilm formation in Staphylococcus aureus

por Henderson, Sara R., Geoghegan, Joan A.
Publicado 2023

High-force catch bonds between the Staphylococcus aureus surface protein SdrE and complement regulator factor H drive immune evasion

por Paiva, Telmo O., Geoghegan, Joan A., Dufrêne, Yves F.
Publicado 2023

Protein-based biofilm matrices in Staphylococci

por Speziale, Pietro, Pietrocola, Giampiero, Foster, Timothy J., Geoghegan, Joan A.
Publicado 2014

The Role of Staphylococcus aureus Virulence Factors in Skin Infection and Their Potential as Vaccine Antigens

por Lacey, Keenan A., Geoghegan, Joan A., McLoughlin, Rachel M.
Publicado 2016

von Willebrand factor-binding protein (vWbp)-activated factor XIII and transglutaminase 2 (TG2) promote cross-linking between FnBPA from Staphylococcus aureus and fibrinogen

por Motta, Chiara, Pellegrini, Angelica, Camaione, Stefano, Geoghegan, Joan, Speziale, Pietro, Barbieri, Giulia, Pietrocola, Giampiero
Publicado 2023

Recruitment of C4b-binding protein is not a complement evasion strategy employed by Staphylococcus aureus

por Li, Shuxian, Bettoni, Serena, Mohlin, Frida, Geoghegan, Joan A., Blom, Anna M., Laabei, Maisem
Publicado 2023

Fibronectin binding protein B binds to loricrin and promotes corneocyte adhesion by Staphylococcus aureus

por da Costa, Thaina M., Viljoen, Albertus, Towell, Aisling M., Dufrêne, Yves F., Geoghegan, Joan A.
Publicado 2022

Interaction of the Staphylococcus aureus Surface Protein FnBPB with Corneodesmosin Involves Two Distinct, Extremely Strong Bonds

por Paiva, Telmo O., Viljoen, Albertus, da Costa, Thaina M., Geoghegan, Joan A., Dufrêne, Yves F.
Publicado 2022

Staphylococcus aureus Fibronectin-Binding Protein A Mediates Cell-Cell Adhesion through Low-Affinity Homophilic Bonds

por Herman-Bausier, Philippe, El-Kirat-Chatel, Sofiane, Foster, Timothy J., Geoghegan, Joan A., Dufrêne, Yves F.
Publicado 2015

Force-Induced Strengthening of the Interaction between Staphylococcus aureus Clumping Factor B and Loricrin

por Vitry, Pauline, Valotteau, Claire, Feuillie, Cécile, Bernard, Simon, Alsteens, David, Geoghegan, Joan A., Dufrêne, Yves F.
Publicado 2017

Staphylococcus aureus clumping factor A is a force-sensitive molecular switch that activates bacterial adhesion

por Herman-Bausier, Philippe, Labate, Cristina, Towell, Aisling M., Derclaye, Sylvie, Geoghegan, Joan A., Dufrêne, Yves F.
Publicado 2018

Clumping factor B is an important virulence factor during Staphylococcus aureus skin infection and a promising vaccine target

por Lacey, Keenan A., Mulcahy, Michelle E., Towell, Aisling M., Geoghegan, Joan A., McLoughlin, Rachel M.
Publicado 2019

Genome sequence of Staphylococcus lugdunensis N920143 allows identification of putative colonization and virulence factors

por Heilbronner, Simon, Holden, Matthew TG, van Tonder, Andries, Geoghegan, Joan A, Foster, Timothy J, Parkhill, Julian, Bentley, Stephen D
Publicado 2011

Molecular Characterization of the Multiple Interactions of SpsD, a Surface Protein from Staphylococcus pseudintermedius, with Host Extracellular Matrix Proteins

por Pietrocola, Giampiero, Geoghegan, Joan A., Rindi, Simonetta, Di Poto, Antonella, Missineo, Antonino, Consalvi, Valerio, Foster, Timothy J., Speziale, Pietro
Publicado 2013

Lessons from the Crystal Structure of the S. aureus Surface Protein Clumping Factor A in Complex With Tefibazumab, an Inhibiting Monoclonal Antibody()

por Ganesh, Vannakambadi K., Liang, Xiaowen, Geoghegan, Joan A., Cohen, Ana Luisa V., Venugopalan, Nagarajan, Foster, Timothy J, Hook, Magnus
Publicado 2016

The Staphylococcus aureus Cell Wall-Anchored Protein Clumping Factor A Is an Important T Cell Antigen

por Lacey, Keenan A., Leech, John M., Lalor, Stephen J., McCormack, Niamh, Geoghegan, Joan A., McLoughlin, Rachel M.
Publicado 2017

Adhesion of Staphylococcus aureus to Corneocytes from Atopic Dermatitis Patients Is Controlled by Natural Moisturizing Factor Levels

por Feuillie, Cécile, Vitry, Pauline, McAleer, Maeve A., Kezic, Sanja, Irvine, Alan D., Geoghegan, Joan A., Dufrêne, Yves F.
Publicado 2018

The immune evasion protein Sbi of Staphylococcus aureus occurs both extracellularly and anchored to the cell envelope by binding lipoteichoic acid

por Smith, Emma Jane, Corrigan, Rebecca M, van der Sluis, Tetje, Gründling, Angelika, Speziale, Pietro, Geoghegan, Joan A, Foster, Timothy J
Publicado 2012

Host-specialized fibrinogen-binding by a bacterial surface protein promotes biofilm formation and innate immune evasion

por Pickering, Amy C., Vitry, Pauline, Prystopiuk, Valeriia, Garcia, Brandon, Höök, Magnus, Schoenebeck, Jeffrey, Geoghegan, Joan A., Dufrêne, Yves F., Fitzgerald, J. Ross
Publicado 2019