Modified Peptide Inhibitors of the Keap1–Nrf2 Protein–Protein Interaction Incorporating Unnatural Amino Acids

por Georgakopoulos, Nikolaos D., Talapatra, Sandeep K., Gatliff, Jemma, Kozielski, Frank, Wells, Geoff
Publicado 2018

Reversible Keap1 inhibitors are preferential pharmacological tools to modulate cellular mitophagy

por Georgakopoulos, Nikolaos D., Frison, Michele, Alvarez, Maria Soledad, Bertrand, Hélène, Wells, Geoff, Campanella, Michelangelo
Publicado 2017

PMI: A ΔΨ(m) Independent Pharmacological Regulator of Mitophagy

por East, Daniel A., Fagiani, Francesca, Crosby, James, Georgakopoulos, Nikolaos D., Bertrand, Hélène, Schaap, Marjolein, Fowkes, Adrian, Wells, Geoff, Campanella, Michelangelo
Publicado 2014

The mycosporine-like amino acids porphyra-334 and shinorine are antioxidants and direct antagonists of Keap1-Nrf2 binding

por Gacesa, Ranko, Lawrence, Karl P., Georgakopoulos, Nikolaos D., Yabe, Kazuo, Dunlap, Walter C., Barlow, David J., Wells, Geoffrey, Young, Antony R., Long, Paul F.
Publicado 2018

Discovery of the first dual GSK3β inhibitor/Nrf2 inducer. A new multitarget therapeutic strategy for Alzheimer’s disease

por Gameiro, Isabel, Michalska, Patrycja, Tenti, Giammarco, Cores, Ángel, Buendia, Izaskun, Rojo, Ana I., Georgakopoulos, Nikolaos D., Hernández-Guijo, Jesús M., Teresa Ramos, María, Wells, Geoffrey, López, Manuela G., Cuadrado, Antonio, Menéndez, J. Carlos, León, Rafael
Publicado 2017