Distinct Neuroblastoma-associated Alterations of PHOX2B Impair Sympathetic Neuronal Differentiation in Zebrafish Models

por Pei, Desheng, Luther, William, Wang, Wenchao, Paw, Barry H., Stewart, Rodney A., George, Rani E.
Publicado 2013

Discovery of 3,5-Diamino-1,2,4-triazole Ureas as Potent Anaplastic Lymphoma Kinase Inhibitors

por Deng, Xianming, Wang, Jinhua, Zhang, Jianming, Sim, Taebo, Kim, Nam Doo, Sasaki, Takaaki, Luther, William, George, Rani E., Jänne, Pasi A., Gray, Nathanael S.
Publicado 2011

Cbx3/HP1γ deficiency confers enhanced tumor-killing capacity on CD8(+) T cells

por Sun, Michael, Ha, Ngoc, Pham, Duc-Hung, Frederick, Megan, Sharma, Bandana, Naruse, Chie, Asano, Masahide, Pipkin, Matthew E., George, Rani E., Thai, To-Ha
Publicado 2017

Synergistic Anti-Tumor Effect of Combining Selective CDK7 and BRD4 Inhibition in Neuroblastoma

por Gao, Yang, Volegova, Marina, Nasholm, Nicole, Das, Sanjukta, Kwiatkowski, Nicholas, Abraham, Brian J., Zhang, Tinghu, Gray, Nathanael S., Gustafson, Clay, Krajewska, Malgorzata, George, Rani E.
Publicado 2022

Genome-Wide Analysis of Neuroblastomas using High-Density Single Nucleotide Polymorphism Arrays

por George, Rani E., Attiyeh, Edward F., Li, Shuli, Moreau, Lisa A., Neuberg, Donna, Li, Cheng, Fox, Edward A., Meyerson, Matthew, Diller, Lisa, Fortina, Paolo, Look, A. Thomas, Maris, John M.
Publicado 2007

Giotto: a toolbox for integrative analysis and visualization of spatial expression data

por Dries, Ruben, Zhu, Qian, Dong, Rui, Eng, Chee-Huat Linus, Li, Huipeng, Liu, Kan, Fu, Yuntian, Zhao, Tianxiao, Sarkar, Arpan, Bao, Feng, George, Rani E., Pierson, Nico, Cai, Long, Yuan, Guo-Cheng
Publicado 2021

Molecular rationale for the use of PI3K/AKT/mTOR pathway inhibitors in combination with crizotinib in ALK-mutated neuroblastoma

por Moore, Nathan F., Azarova, Anna M., Bhatnagar, Namrata, Ross, Kenneth N., Drake, Lauren E., Frumm, Stacey, Liu, Qinsong S., Christie, Amanda L., Sanda, Takaomi, Chesler, Louis, Kung, Andrew L., Gray, Nathanael S., Stegmaier, Kimberly, George, Rani E.
Publicado 2014

Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration

por Huang, Hao, Gont, Alexander, Kee, Lynn, Dries, Ruben, Pfeifer, Kathrin, Sharma, Bandana, Debruyne, David N., Harlow, Matthew, Sengupta, Satyaki, Guan, Jikui, Yeung, Caleb M., Wang, Wenchao, Hallberg, Bengt, Palmer, Ruth H., Irwin, Meredith S., George, Rani E.
Publicado 2021

Expression of the neuron-specific protein CHD5 is an independent marker of outcome in neuroblastoma

por Garcia, Idoia, Mayol, Gemma, Rodríguez, Eva, Suñol, Mariona, Gershon, Timothy R, Ríos, José, Cheung, Nai-Kong V, Kieran, Mark W, George, Rani E, Perez-Atayde, Antonio R, Casala, Carla, Galván, Patricia, de Torres, Carmen, Mora, Jaume, Lavarino, Cinzia
Publicado 2010

mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis

por Choe, Junho, Lin, Shuibin, Zhang, Wencai, Liu, Qi, Wang, Longfei, Ramirez-Moya, Julia, Du, Peng, Kim, Wantae, Tang, Shaojun, Sliz, Piotr, Santisteban, Pilar, George, Rani E., Richards, William G., Wong, Kwok-Kin, Locker, Nicolas, Slack, Frank J., Gregory, Richard I.
Publicado 2018

CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation

por Krajewska, Malgorzata, Dries, Ruben, Grassetti, Andrew V., Dust, Sofia, Gao, Yang, Huang, Hao, Sharma, Bandana, Day, Daniel S., Kwiatkowski, Nicholas, Pomaville, Monica, Dodd, Oliver, Chipumuro, Edmond, Zhang, Tinghu, Greenleaf, Arno L., Yuan, Guo-Cheng, Gray, Nathanael S., Young, Richard A., Geyer, Matthias, Gerber, Scott A., George, Rani E.
Publicado 2019

Activating mutations in ALK provide a therapeutic target in neuroblastoma

por George, Rani E., Sanda, Takaomi, Hanna, Megan, Fröhling, Stefan, Luther, William, Zhang, Jianming, Ahn, Yebin, Zhou, Wenjun, London, Wendy B., McGrady, Patrick, Xue, Liquan, Zozulya, Sergey, Gregor, Vlad, Webb, Thomas R., Gray, Nathanael S., Gilliland, D. Gary, Diller, Lisa, Greulich, Heidi, Morris, Stephan W., Meyerson, Matthew, Look, A. Thomas
Publicado 2008

Epigenetic modulation of neuroblastoma enhances T cell and NK cell immunogenicity by inducing a tumor-cell lineage switch

por Cornel, Annelisa M, Dunnebach, Ester, Hofman, Damon A, Das, Sanjukta, Sengupta, Satyaki, van den Ham, Femke, Wienke, Judith, Strijker, Josephine G M, van den Beemt, Denise A M H, Essing, Anke H W, Koopmans, Bianca, Engels, Sem A G, Lo Presti, Vania, Szanto, Celina S, George, Rani E, Molenaar, Jan J, van Heesch, Sebastiaan, Dierselhuis, Miranda P, Nierkens, S
Publicado 2022

Forty-five patient-derived xenografts capture the clinical and biological heterogeneity of Wilms tumor

por Murphy, Andrew J., Chen, Xiang, Pinto, Emilia M., Williams, Justin S., Clay, Michael R., Pounds, Stanley B., Cao, Xueyuan, Shi, Lei, Lin, Tong, Neale, Geoffrey, Morton, Christopher L., Woolard, Mary A., Mulder, Heather L., Gil, Hyea Jin, Rehg, Jerold E., Billups, Catherine A., Harlow, Matthew L., Dome, Jeffrey S., Houghton, Peter J., Easton, John, Zhang, Jinghui, George, Rani E., Zambetti, Gerard P., Davidoff, Andrew M.
Publicado 2019

JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma

por Wong, Matthew, Sun, Yuting, Xi, Zhichao, Milazzo, Giorgio, Poulos, Rebecca C., Bartenhagen, Christoph, Bell, Jessica L., Mayoh, Chelsea, Ho, Nicholas, Tee, Andrew E., Chen, Xiaoqiong, Li, Yang, Ciaccio, Roberto, Liu, Pei Y., Jiang, Chen C., Lan, Qing, Jayatilleke, Nisitha, Cheung, Belamy B., Haber, Michelle, Norris, Murray D., Zhang, Xu D., Marshall, Glenn M., Wang, Jenny Y., Hüttelmaier, Stefan, Fischer, Matthias, Wong, Jason W. H., Xu, Hongxi, Perini, Giovanni, Dong, Qihan, George, Rani E., Liu, Tao
Publicado 2019

MYCN amplification and ATRX mutations are incompatible in neuroblastoma

por Zeineldin, Maged, Federico, Sara, Chen, Xiang, Fan, Yiping, Xu, Beisi, Stewart, Elizabeth, Zhou, Xin, Jeon, Jongrye, Griffiths, Lyra, Nguyen, Rosa, Norrie, Jackie, Easton, John, Mulder, Heather, Yergeau, Donald, Liu, Yanling, Wu, Jianrong, Van Ryn, Collin, Naranjo, Arlene, Hogarty, Michael D., Kamiński, Marcin M., Valentine, Marc, Pruett-Miller, Shondra M., Pappo, Alberto, Zhang, Jinghui, Clay, Michael R., Bahrami, Armita, Vogel, Peter, Lee, Seungjae, Shelat, Anang, Sarthy, Jay F., Meers, Michael P., George, Rani E., Mardis, Elaine R., Wilson, Richard K., Henikoff, Steven, Downing, James R., Dyer, Michael A.
Publicado 2020