Metabolic and functional specialisations of the pancreatic beta cell: gene disallowance, mitochondrial metabolism and intercellular connectivity

por Rutter, Guy A., Georgiadou, Eleni, Martinez-Sanchez, Aida, Pullen, Timothy J.
Publicado 2020

A rare case of congenital plexiform fibrohistiocytic tumor of the foot in a 4-year-old boy: case report and literature review

por Demiri, Efterpi, Georgiadou, Eleni, Goula, Olga-Christina, Tzorakoeleftheraki, Sofia-Eleni, Karagergou, Eleni, Hytiroglou, Prodromos
Publicado 2021

A cross-sectional study of explainable machine learning in Alzheimer’s disease: diagnostic classification using MR radiomic features

por Leandrou, Stephanos, Lamnisos, Demetris, Bougias, Haralabos, Stogiannos, Nikolaos, Georgiadou, Eleni, Achilleos, K. G., Pattichis, Constantinos S.
Publicado 2023

Loss of β-cell identity and diabetic phenotype in mice caused by disruption of CNOT3-dependent mRNA deadenylation

por Mostafa, Dina, Yanagiya, Akiko, Georgiadou, Eleni, Wu, Yibo, Stylianides, Theodoros, Rutter, Guy A., Suzuki, Toru, Yamamoto, Tadashi
Publicado 2020

Intravital imaging of islet Ca(2+) dynamics reveals enhanced β cell connectivity after bariatric surgery in mice

por Akalestou, Elina, Suba, Kinga, Lopez-Noriega, Livia, Georgiadou, Eleni, Chabosseau, Pauline, Gallie, Alasdair, Wretlind, Asger, Legido-Quigley, Cristina, Leclerc, Isabelle, Salem, Victoria, Rutter, Guy A.
Publicado 2021

Author Correction: Intravital imaging of islet Ca(2+) dynamics reveals enhanced β cell connectivity after bariatric surgery in mice

por Akalestou, Elina, Suba, Kinga, Lopez-Noriega, Livia, Georgiadou, Eleni, Chabosseau, Pauline, Gallie, Alasdair, Wretlind, Asger, Legido-Quigley, Cristina, Leclerc, Isabelle, Salem, Victoria, Rutter, Guy A.
Publicado 2021

Impact of an SLC30A8 loss-of-function variant on the pancreatic distribution of zinc and manganese: laser ablation-ICP-MS and positron emission tomography studies in mice

por Firth, George, Georgiadou, Eleni, Griffiths, Alexander, Amrahli, Maral, Kim, Jana, Yu, Zilin, Hu, Ming, Stewart, Theodora J., Leclerc, Isabelle, Okamoto, Haruka, Gomez, Daniel, Blower, Philip J., Rutter, Guy A.
Publicado 2023

Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase

por Nguyen-Tu, Marie-Sophie, Harris, Joseph, Martinez-Sanchez, Aida, Chabosseau, Pauline, Hu, Ming, Georgiadou, Eleni, Pollard, Alice, Otero, Pablo, Lopez-Noriega, Livia, Leclerc, Isabelle, Sakamoto, Kei, Schmoll, Dieter, Smith, David M., Carling, David, Rutter, Guy A.
Publicado 2022

A surrogate of Roux-en-Y gastric bypass (the enterogastro anastomosis surgery) regulates multiple beta-cell pathways during resolution of diabetes in ob/ob mice

por Amouyal, Chloé, Castel, Julien, Guay, Claudiane, Lacombe, Amélie, Denom, Jessica, Migrenne-Li, Stéphanie, Rouault, Christine, Marquet, Florian, Georgiadou, Eleni, Stylianides, Theodoros, Luquet, Serge, Le Stunff, Hervé, Scharfmann, Raphael, Clément, Karine, Rutter, Guy A., Taboureau, Olivier, Magnan, Christophe, Regazzi, Romano, Andreelli, Fabrizio
Publicado 2020

Homocysteine Metabolism Pathway Is Involved in the Control of Glucose Homeostasis: A Cystathionine Beta Synthase Deficiency Study in Mouse

por Cruciani-Guglielmacci, Céline, Meneyrol, Kelly, Denom, Jessica, Kassis, Nadim, Rachdi, Latif, Makaci, Fatna, Migrenne-Li, Stéphanie, Daubigney, Fabrice, Georgiadou, Eleni, Denis, Raphaël G., Rodriguez Sanchez-Archidona, Ana, Paul, Jean-Louis, Thorens, Bernard, Rutter, Guy A., Magnan, Christophe, Le Stunff, Hervé, Janel, Nathalie
Publicado 2022

The pore-forming subunit MCU of the mitochondrial Ca(2+) uniporter is required for normal glucose-stimulated insulin secretion in vitro and in vivo in mice

por Georgiadou, Eleni, Haythorne, Elizabeth, Dickerson, Matthew T., Lopez-Noriega, Livia, Pullen, Timothy J., da Silva Xavier, Gabriela, Davis, Samuel P. X., Martinez-Sanchez, Aida, Semplici, Francesca, Rizzuto, Rosario, McGinty, James A., French, Paul M., Cane, Matthew C., Jacobson, David A., Leclerc, Isabelle, Rutter, Guy A.
Publicado 2020

Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated β-Cell Connectivity and Insulin Secretion

por Georgiadou, Eleni, Muralidharan, Charanya, Martinez, Michelle, Chabosseau, Pauline, Akalestou, Elina, Tomas, Alejandra, Wern, Fiona Yong Su, Stylianides, Theodoros, Wretlind, Asger, Legido-Quigley, Cristina, Jones, Ben, Lopez-Noriega, Livia, Xu, Yanwen, Gu, Guoqiang, Alsabeeh, Nour, Cruciani-Guglielmacci, Céline, Magnan, Christophe, Ibberson, Mark, Leclerc, Isabelle, Ali, Yusuf, Soleimanpour, Scott A., Linnemann, Amelia K., Rodriguez, Tristan A., Rutter, Guy A.
Publicado 2022

Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis

por Mousavy Gharavy, S. Neda, Owen, Bryn M., Millership, Steven J., Chabosseau, Pauline, Pizza, Grazia, Martinez-Sanchez, Aida, Tasoez, Emirhan, Georgiadou, Eleni, Hu, Ming, Fine, Nicholas H. F., Jacobson, David A., Dickerson, Matthew T., Idevall-Hagren, Olof, Montoya, Alex, Kramer, Holger, Mehta, Zenobia, Withers, Dominic J., Ninov, Nikolay, Gadue, Paul J., Cardenas-Diaz, Fabian L., Cruciani-Guglielmacci, Céline, Magnan, Christophe, Ibberson, Mark, Leclerc, Isabelle, Voz, Marianne, Rutter, Guy A.
Publicado 2021

The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis

por Carrat, Gaelle R., Haythorne, Elizabeth, Tomas, Alejandra, Haataja, Leena, Müller, Andreas, Arvan, Peter, Piunti, Alexandra, Cheng, Kaiying, Huang, Mutian, Pullen, Timothy J., Georgiadou, Eleni, Stylianides, Theodoros, Amirruddin, Nur Shabrina, Salem, Victoria, Distaso, Walter, Cakebread, Andrew, Heesom, Kate J., Lewis, Philip A., Hodson, David J., Briant, Linford J., Fung, Annie C.H., Sessions, Richard B., Alpy, Fabien, Kong, Alice P.S., Benke, Peter I., Torta, Federico, Teo, Adrian Kee Keong, Leclerc, Isabelle, Solimena, Michele, Wigley, Dale B., Rutter, Guy A.
Publicado 2020

Identification of biomarkers for glycaemic deterioration in type 2 diabetes

por Slieker, Roderick C., Donnelly, Louise A., Akalestou, Elina, Lopez-Noriega, Livia, Melhem, Rana, Güneş, Ayşim, Abou Azar, Frederic, Efanov, Alexander, Georgiadou, Eleni, Muniangi-Muhitu, Hermine, Sheikh, Mahsa, Giordano, Giuseppe N., Åkerlund, Mikael, Ahlqvist, Emma, Ali, Ashfaq, Banasik, Karina, Brunak, Søren, Barovic, Marko, Bouland, Gerard A., Burdet, Frédéric, Canouil, Mickaël, Dragan, Iulian, Elders, Petra J. M., Fernandez, Celine, Festa, Andreas, Fitipaldi, Hugo, Froguel, Phillippe, Gudmundsdottir, Valborg, Gudnason, Vilmundur, Gerl, Mathias J., van der Heijden, Amber A., Jennings, Lori L., Hansen, Michael K., Kim, Min, Leclerc, Isabelle, Klose, Christian, Kuznetsov, Dmitry, Mansour Aly, Dina, Mehl, Florence, Marek, Diana, Melander, Olle, Niknejad, Anne, Ottosson, Filip, Pavo, Imre, Duffin, Kevin, Syed, Samreen K., Shaw, Janice L., Cabrera, Over, Pullen, Timothy J., Simons, Kai, Solimena, Michele, Suvitaival, Tommi, Wretlind, Asger, Rossing, Peter, Lyssenko, Valeriya, Legido Quigley, Cristina, Groop, Leif, Thorens, Bernard, Franks, Paul W., Lim, Gareth E., Estall, Jennifer, Ibberson, Mark, Beulens, Joline W. J., ’t Hart, Leen M, Pearson, Ewan R., Rutter, Guy A.
Publicado 2023