Transforming epitope-specific gp120 monomer-based probes into immunogens with N-linked glycan masking

por Chuang, G, Boyington, JC, Nabel, GJ, Kwong, PD, Georgiev, I
Publicado 2012

Partial germline reversions can increase VRC07 potency and breadth

por Rudicell, RS, Georgiev, I, Yang, Z, O'Dell, S, Kwon, Y, Zhu, J, Wu, X, Kwong, PD, Mascola, JR, Nabel, GJ
Publicado 2012

Hyperglycosylated resurfaced stabilized GP120 core as an immunogen elicits antibodies targeted at the CD4-binding site

por Dai, K, Boyington, JC, Shi, W, Schmidt, SD, Georgiev, I, Lingwood, D, Kwong, PD, Mascola, JR, Yang, Z, Nabel, GJ
Publicado 2012

Structure-guided modification and optimization of antibody VRC07

por Kwon, Y, Georgiev, I, O'Dell, S, Shi, W, Chuang, G, Yang, Y, Zhang, B, Zhu, J, Nabel, GJ, Mascola, JR, Kwong, PD
Publicado 2012

Structural definition of a novel CD4-induced epitope that is targeted by a single-headed immunoglobulin to effect broad and potent HIV neutralization

por Acharya, P, Luongo, TS, Matz, J, Schmidt, SD, Chuang, G, Georgiev, I, Kessler, P, Yang, Y, Chames, P, Martin, L, Mascola, JR, Kwong, PD
Publicado 2012

Characteristics of HIV-1 gp120 molecules that bind ancestor, intermediate and mature forms of VRC01-like antibodies

por Joyce, M, Zhang, B, Zhou, T, Moquin, S, Wu, X, Louder, M, Zhang, Z, Georgiev, I, Zhu, J, Shapiro, L, Mascola, JR, Nabel, GJ, Kwong, PD
Publicado 2012

Design of epitope-specific probes for sera analysis and antibody isolation

por Georgiev, I, Acharya, P, Schmidt, SD, Li, Y, Wycuff, D, Ofek, G, Doria-Rose, N, Luongo, TS, Yang, Y, Zhou, T, Donald, BR, Mascola, JR, Kwong, PD
Publicado 2012

A short segment in the HIV-1 gp120 V1/V2 region is a major determinant of neutralization resistance to PG9-like antibodies

por Doria-Rose, NA, Georgiev, I, Staupe, RP, O'Dell, S, Chuang, G, Gorman, J, McLellan, JS, Pancera, M, Bonsignori, M, Haynes, BF, Burton, DR, Koff, WC, Kwong, PD, Mascola, JR
Publicado 2012