Crystal structure of Pseudomonas aeruginosa FabB C161A, a template for structure-based design for new antibiotics

por Yadrykhins'ky, Vladyslav, Georgiou, Charis, Brenk, Ruth
Publicado 2022

Stretchable Composite Acoustic Transducer for Wearable Monitoring of Vital Signs

por Cotur, Yasin, Kasimatis, Michael, Kaisti, Matti, Olenik, Selin, Georgiou, Charis, Güder, Fira
Publicado 2020

An Experimental Toolbox for Structure‐Based Hit Discovery for P. aeruginosa FabF, a Promising Target for Antibiotics

por Espeland, Ludvik Olai, Georgiou, Charis, Klein, Raphael, Bhukya, Hemalatha, Haug, Bengt Erik, Underhaug, Jarl, Mainkar, Prathama S., Brenk, Ruth
Publicado 2021

Dynamic design: manipulation of millisecond timescale motions on the energy landscape of cyclophilin A

por Juárez-Jiménez, Jordi, Gupta, Arun A., Karunanithy, Gogulan, Mey, Antonia S. J. S., Georgiou, Charis, Ioannidis, Harris, De Simone, Alessio, Barlow, Paul N., Hulme, Alison N., Walkinshaw, Malcolm D., Baldwin, Andrew J., Michel, Julien
Publicado 2020

A computationally designed binding mode flip leads to a novel class of potent tri-vector cyclophilin inhibitors

por De Simone, Alessio, Georgiou, Charis, Ioannidis, Harris, Gupta, Arun A., Juárez-Jiménez, Jordi, Doughty-Shenton, Dahlia, Blackburn, Elizabeth A., Wear, Martin A., Richards, Jonathan P., Barlow, Paul N., Carragher, Neil, Walkinshaw, Malcolm D., Hulme, Alison N., Michel, Julien
Publicado 2018