PET Oncological Radiopharmaceuticals: Current Status and Perspectives

por Lin, Mai, Coll, Ryan P., Cohen, Allison S., Georgiou, Dimitra K., Manning, Henry Charles
Publicado 2022

ENOblock Does Not Inhibit the Activity of the Glycolytic Enzyme Enolase

por Satani, Nikunj, Lin, Yu-Hsi, Hammoudi, Naima, Raghavan, Sudhir, Georgiou, Dimitra K., Muller, Florian L.
Publicado 2016

Feasibility of [(18)F]FSPG PET for Early Response Assessment to Combined Blockade of EGFR and Glutamine Metabolism in Wild-Type KRAS Colorectal Cancer

por Bae, Seong-Woo, Wang, Jianbo, Georgiou, Dimitra K., Wen, Xiaoxia, Cohen, Allison S., Geng, Ling, Tantawy, Mohammed Noor, Manning, H. Charles
Publicado 2023

Impaired anaplerosis is a major contributor to glycolysis inhibitor toxicity in glioma

por Khadka, Sunada, Arthur, Kenisha, Barekatain, Yasaman, Behr, Eliot, Washington, Mykia, Ackroyd, Jeffrey, Crowley, Kaitlyn, Suriyamongkol, Pornpa, Lin, Yu-Hsi, Pham, Cong-Dat, Zielinski, Rafal, Trujillo, Marissa, Galligan, James, Georgiou, Dimitra K., Asara, John, Muller, Florian
Publicado 2021

Pharmacokinetics of Orally Administered GS-441524 in Dogs

por Yan, Victoria C., Pham, Cong-Dat, Yan, Matthew J., Yan, Alexander J., Khadka, Sunada, Arthur, Kenisha, Ackroyd, Jeffrey J., Georgiou, Dimitra K., Roon, Laura E., Bushman, Lane R., Anderson, Peter L., Li, Chun, Muller, Florian L.
Publicado 2021

AICAR Prevents Heat Induced Sudden Death in RyR1 Mutant Mice Independent of AMPK Activation

por Lanner, Johanna T., Georgiou, Dimitra K., Dagnino-Acosta, Adan, Ainbinder, Alina, Cheng, Qing, Joshi, Aditya D., Chen, Zanwen, Yarotskyy, Viktor, Oakes, Joshua M., Lee, Chang Seok, Monroe, Tanner O., Santillan, Arturo, Dong, Keke, Goodyear, Laurie, Ismailov, Iskander I., Rodney, George G., Dirksen, Robert T., Hamilton, Susan L.
Publicado 2012

A chemical chaperone improves muscle function in mice with a RyR1 mutation

por Lee, Chang Seok, Hanna, Amy D., Wang, Hui, Dagnino-Acosta, Adan, Joshi, Aditya D., Knoblauch, Mark, Xia, Yan, Georgiou, Dimitra K., Xu, Jianjun, Long, Cheng, Amano, Hisayuki, Reynolds, Corey, Dong, Keke, Martin, John C., Lagor, William R., Rodney, George G., Sahin, Ergun, Sewry, Caroline, Hamilton, Susan L.
Publicado 2017

Ca(2+) permeation and/or binding to Ca(V)1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function

por Lee, Chang Seok, Dagnino-Acosta, Adan, Yarotskyy, Viktor, Hanna, Amy, Lyfenko, Alla, Knoblauch, Mark, Georgiou, Dimitra K, Poché, Ross A, Swank, Michael W, Long, Cheng, Ismailov, Iskander I, Lanner, Johanna, Tran, Ted, Dong, KeKe, Rodney, George G, Dickinson, Mary E, Beeton, Christine, Zhang, Pumin, Dirksen, Robert T, Hamilton, Susan L
Publicado 2015

Prodrugs of a 1-Hydroxy-2-oxopiperidin-3-yl Phosphonate Enolase Inhibitor for the Treatment of ENO1-Deleted Cancers

por Yan, Victoria C., Pham, Cong-Dat, Ballato, Elliot S., Yang, Kristine L., Arthur, Kenisha, Khadka, Sunada, Barekatain, Yasaman, Shrestha, Prakriti, Tran, Theresa, Poral, Anton H., Washington, Mykia, Raghavan, Sudhir, Czako, Barbara, Pisaneschi, Federica, Lin, Yu-Hsi, Satani, Nikunj, Hammoudi, Naima, Ackroyd, Jeffrey J., Georgiou, Dimitra K., Millward, Steven W., Muller, Florian L.
Publicado 2022

Anaplerotic nutrient stress drives synergy of angiogenesis inhibitors with therapeutics targeting tumor metabolism

por Khadka, Sunada, Lin, Yu-Hsi, Ackroyd, Jeffrey, Chen, Yi-An, Sheng, Yanghui, Qian, Wubin, Guo, Sheng, Chen, Yining, Behr, Eliot, Barekatain, Yasaman, Uddin, Nasir, Arthur, Kenisha, Yan, Victoria, Hsu, Wen-Hao, Chang, Qing, Poral, Anton, Tran, Theresa, Chaurasia, Surendra, Georgiou, Dimitra K., Asara, John M., Barthel, Floris P., Millward, Steve W., DePinho, Ronald A., Muller, Florian L.
Publicado 2023

Adaptive thermogenesis enhances the life-threatening response to heat in mice with an Ryr1 mutation

por Wang, Hui J., Lee, Chang Seok, Yee, Rachel Sue Zhen, Groom, Linda, Friedman, Inbar, Babcock, Lyle, Georgiou, Dimitra K., Hong, Jin, Hanna, Amy D., Recio, Joseph, Choi, Jong Min, Chang, Ting, Agha, Nadia H., Romero, Jonathan, Sarkar, Poonam, Voermans, Nicol, Gaber, M. Waleed, Jung, Sung Yun, Baker, Matthew L., Pautler, Robia G., Dirksen, Robert T., Riazi, Sheila, Hamilton, Susan L.
Publicado 2020

Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine

por Barekatain, Yasaman, Ackroyd, Jeffrey J., Yan, Victoria C., Khadka, Sunada, Wang, Lin, Chen, Ko-Chien, Poral, Anton H., Tran, Theresa, Georgiou, Dimitra K., Arthur, Kenisha, Lin, Yu-Hsi, Satani, Nikunj, Ballato, Elliot S., Behr, Eliot I., deCarvalho, Ana C., Verhaak, Roel G. W., de Groot, John, Huse, Jason T., Asara, John M., Kalluri, Raghu, Muller, Florian L.
Publicado 2021

An Enolase Inhibitor for the Targeted Treatment of ENO1-Deleted Cancers

por Lin, Yu-Hsi, Satani, Nikunj, Hammoudi, Naima, Yan, Victoria C., Barekatain, Yasaman, Khadka, Sunada, Ackroyd, Jeffrey J., Georgiou, Dimitra K., Pham, Cong-Dat, Arthur, Kenisha, Maxwell, David, Peng, Zhenghong, Leonard, Paul G., Czako, Barbara, Pisaneschi, Federica, Mandal, Pijus, Sun, Yuting, Zielinski, Rafal, Pando, Susana Castro, Wang, Xiaobo, Tran, Theresa, Xu, Quanyu, Wu, Qi, Jiang, Yongying, Kang, Zhijun, Asara, John M., Priebe, Waldemar, Bornmann, William, Marszalek, Joseph R., DePinho, Ronald A., Muller, Florian L.
Publicado 2020