IL-1β Is Upregulated in the Diabetic Retina and Retinal Vessels: Cell-Specific Effect of High Glucose and IL-1β Autostimulation

por Liu, Yang, Biarnés Costa, Montserrat, Gerhardinger, Chiara
Publicado 2012

High-throughput functional analysis of regulatory variants using a massively parallel reporter assay

por Delfosse, Kate, Gerhardinger, Chiara, Rinn, John L., Maass, Philipp G.
Publicado 2023

The Transforming Growth Factor-β Pathway Is a Common Target of Drugs That Prevent Experimental Diabetic Retinopathy

por Gerhardinger, Chiara, Dagher, Zeina, Sebastiani, Paola, Park, Yong Seek, Lorenzi, Mara
Publicado 2009

Decreased Cerebrovascular Brain-Derived Neurotrophic Factor–Mediated Neuroprotection in the Diabetic Brain

por Navaratna, Deepti, Guo, Shu-zhen, Hayakawa, Kazhuhide, Wang, Xiaoying, Gerhardinger, Chiara, Lo, Eng H.
Publicado 2011

Chromatin environment, transcriptional regulation, and splicing distinguish lincRNAs and mRNAs

por Melé, Marta, Mattioli, Kaia, Mallard, William, Shechner, David M., Gerhardinger, Chiara, Rinn, John L.
Publicado 2017

In vivo Firre and Dxz4 deletion elucidates roles for autosomal gene regulation

por Andergassen, Daniel, Smith, Zachary D, Lewandowski, Jordan P, Gerhardinger, Chiara, Meissner, Alexander, Rinn, John L
Publicado 2019

Cis and trans effects differentially contribute to the evolution of promoters and enhancers

por Mattioli, Kaia, Oliveros, Winona, Gerhardinger, Chiara, Andergassen, Daniel, Maass, Philipp G., Rinn, John L., Melé, Marta
Publicado 2020

High-throughput functional analysis of lncRNA core promoters elucidates rules governing tissue specificity

por Mattioli, Kaia, Volders, Pieter-Jan, Gerhardinger, Chiara, Lee, James C., Maass, Philipp G., Melé, Marta, Rinn, John L.
Publicado 2019

Endothelial Progenitor Cells Carrying Monocyte Markers Are Selectively Abnormal in Type 1 Diabetic Patients With Early Retinopathy

por Zerbini, Gianpaolo, Maestroni, Anna, Palini, Alessio, Tremolada, Gemma, Lattanzio, Rosangela, Maestroni, Silvia, Pastore, Matteo Rocco, Secchi, Antonio, Bonfanti, Riccardo, Gerhardinger, Chiara, Lorenzi, Mara
Publicado 2012

Genome-wide CRISPR interference screen identifies long non-coding RNA loci required for differentiation and pluripotency

por Haswell, Jeffrey R., Mattioli, Kaia, Gerhardinger, Chiara, Maass, Philipp G., Foster, Daniel J., Peinado, Paola, Wang, Xiaofeng, Medina, Pedro P., Rinn, John L., Slack, Frank J.
Publicado 2021

High‐throughput identification of RNA nuclear enrichment sequences

por Shukla, Chinmay J, McCorkindale, Alexandra L, Gerhardinger, Chiara, Korthauer, Keegan D, Cabili, Moran N, Shechner, David M, Irizarry, Rafael A, Maass, Philipp G, Rinn, John L
Publicado 2018

In vivo Ebola virus infection leads to a strong innate response in circulating immune cells

por Caballero, Ignacio S., Honko, Anna N., Gire, Stephen K., Winnicki, Sarah M., Melé, Marta, Gerhardinger, Chiara, Lin, Aaron E., Rinn, John L., Sabeti, Pardis C., Hensley, Lisa E., Connor, John H.
Publicado 2016

Resolving mechanisms of immune‐mediated disease in primary CD4 T cells

por Bourges, Christophe, Groff, Abigail F, Burren, Oliver S, Gerhardinger, Chiara, Mattioli, Kaia, Hutchinson, Anna, Hu, Theodore, Anand, Tanmay, Epping, Madeline W, Wallace, Chris, Smith, Kenneth GC, Rinn, John L, Lee, James C
Publicado 2020

The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis

por Lewandowski, Jordan P., Lee, James C., Hwang, Taeyoung, Sunwoo, Hongjae, Goldstein, Jill M., Groff, Abigail F., Chang, Nydia P., Mallard, William, Williams, Adam, Henao-Meija, Jorge, Flavell, Richard A., Lee, Jeannie T., Gerhardinger, Chiara, Wagers, Amy J., Rinn, John L.
Publicado 2019

The Tug1 lncRNA locus is essential for male fertility

por Lewandowski, Jordan P., Dumbović, Gabrijela, Watson, Audrey R., Hwang, Taeyoung, Jacobs-Palmer, Emily, Chang, Nydia, Much, Christian, Turner, Kyle M., Kirby, Christopher, Rubinstein, Nimrod D., Groff, Abigail F., Liapis, Steve C., Gerhardinger, Chiara, Bester, Assaf, Pandolfi, Pier Paolo, Clohessy, John G., Hoekstra, Hopi E., Sauvageau, Martin, Rinn, John L.
Publicado 2020

Multiple knockout mouse models reveal lincRNAs are required for life and brain development

por Sauvageau, Martin, Goff, Loyal A, Lodato, Simona, Bonev, Boyan, Groff, Abigail F, Gerhardinger, Chiara, Sanchez-Gomez, Diana B, Hacisuleyman, Ezgi, Li, Eric, Spence, Matthew, Liapis, Stephen C, Mallard, William, Morse, Michael, Swerdel, Mavis R, D’Ecclessis, Michael F, Moore, Jennifer C, Lai, Venus, Gong, Guochun, Yancopoulos, George D, Frendewey, David, Kellis, Manolis, Hart, Ronald P, Valenzuela, David M, Arlotta, Paola, Rinn, John L
Publicado 2013

Dynamic changes during the treatment of pancreatic cancer

por Wolff, Robert A., Wang-Gillam, Andrea, Alvarez, Hector, Tiriac, Hervé, Engle, Dannielle, Hou, Shurong, Groff, Abigail F., San Lucas, Anthony, Bernard, Vincent, Allenson, Kelvin, Castillo, Jonathan, Kim, Dong, Mulu, Feven, Huang, Jonathan, Stephens, Bret, Wistuba, Ignacio I., Katz, Matthew, Varadhachary, Gauri, Park, YoungKyu, Hicks, James, Chinnaiyan, Arul, Scampavia, Louis, Spicer, Timothy, Gerhardinger, Chiara, Maitra, Anirban, Tuveson, David, Rinn, John, Lizee, Gregory, Yee, Cassian, Levine, Arnold J.
Publicado 2018