Leveraging GPCR signaling in thermogenic fat to counteract metabolic diseases

por Sveidahl Johansen, Olivia, Ma, Tao, Gerhart-Hines, Zachary
Publicado 2022

Cold-induction of afadin in brown fat supports its thermogenic capacity

por Lundh, Morten, Altıntaş, Ali, Tozzi, Marco, Fabre, Odile, Ma, Tao, Shamsi, Farnaz, Gerhart-Hines, Zachary, Barrès, Romain, Tseng, Yu-Hua, Emanuelli, Brice
Publicado 2021

NAMPT-mediated NAD(+) biosynthesis is indispensable for adipose tissue plasticity and development of obesity

por Nielsen, Karen Nørgaard, Peics, Julia, Ma, Tao, Karavaeva, Iuliia, Dall, Morten, Chubanava, Sabina, Basse, Astrid L., Dmytriyeva, Oksana, Treebak, Jonas T., Gerhart-Hines, Zachary
Publicado 2018

Lipolysis regulates major transcriptional programs in brown adipocytes

por Markussen, Lasse K., Rondini, Elizabeth A., Johansen, Olivia Sveidahl, Madsen, Jesper G. S., Sustarsic, Elahu G., Marcher, Ann-Britt, Hansen, Jacob B., Gerhart-Hines, Zachary, Granneman, James G., Mandrup, Susanne
Publicado 2022

Housing temperature influences exercise training adaptations in mice

por Raun, Steffen H., Henriquez-Olguín, Carlos, Karavaeva, Iuliia, Ali, Mona, Møller, Lisbeth L. V., Kot, Witold, Castro-Mejía, Josué L., Nielsen, Dennis Sandris, Gerhart-Hines, Zachary, Richter, Erik A., Sylow, Lykke
Publicado 2020

The Nuclear Receptor Rev-erbα Controls Circadian Thermogenic Plasticity

por Gerhart-Hines, Zachary, Feng, Dan, Emmett, Matthew J., Everett, Logan J., Loro, Emanuele, Briggs, Erika R., Bugge, Anne, Hou, Catherine, Ferrara, Christine, Seale, Patrick, Pryma, Daniel A., Khurana, Tejvir S., Lazar, Mitchell A.
Publicado 2013

NAMPT-dependent NAD(+) biosynthesis controls circadian metabolism in a tissue-specific manner

por Basse, Astrid L., Nielsen, Karen N., Karavaeva, Iuliia, Ingerslev, Lars R., Ma, Tao, Havelund, Jesper F., Nielsen, Thomas S., Frost, Mikkel, Peics, Julia, Dalbram, Emilie, Dall, Morten, Zierath, Juleen R., Barrès, Romain, Færgeman, Nils J., Treebak, Jonas T., Gerhart-Hines, Zachary
Publicado 2023

White adipose remodeling during browning in mice involves YBX1 to drive thermogenic commitment

por Rabiee, Atefeh, Plucińska, Kaja, Isidor, Marie Sophie, Brown, Erin Louise, Tozzi, Marco, Sidoli, Simone, Petersen, Patricia Stephanie S., Agueda-Oyarzabal, Marina, Torsetnes, Silje Bøen, Chehabi, Galal Nazih, Lundh, Morten, Altıntaş, Ali, Barrès, Romain, Jensen, Ole Nørregaard, Gerhart-Hines, Zachary, Emanuelli, Brice
Publicado 2020

Histone Deacetylase 3 Prepares Brown Adipose Tissue For Acute Thermogenic Challenge

por Emmett, Matthew J., Lim, Hee-Woong, Jager, Jennifer, Richter, Hannah J., Adlanmerini, Marine, Peed, Lindsey C., Briggs, Erika R., Steger, David J., Ma, Tao, Sims, Carrie A., Baur, Joseph A., Pei, Liming, Won, Kyoung-Jae, Seale, Patrick, Gerhart-Hines, Zachary, Lazar, Mitchell A.
Publicado 2017

Thyroid hormone receptor α in skeletal muscle is essential for T3‐mediated increase in energy expenditure

por Nicolaisen, Trine S., Klein, Anders B., Dmytriyeva, Oksana, Lund, Jens, Ingerslev, Lars R., Fritzen, Andreas M., Carl, Christian S., Lundsgaard, Anne‐Marie, Frost, Mikkel, Ma, Tao, Schjerling, Peter, Gerhart‐Hines, Zachary, Flamant, Frederic, Gauthier, Karine, Larsen, Steen, Richter, Erik A., Kiens, Bente, Clemmensen, Christoffer
Publicado 2020

Altered brown fat thermoregulation and enhanced cold-induced thermogenesis in young, healthy, winter-swimming men

por Søberg, Susanna, Löfgren, Johan, Philipsen, Frederik E., Jensen, Michal, Hansen, Adam E., Ahrens, Esben, Nystrup, Kristin B., Nielsen, Rune D., Sølling, Christine, Wedell-Neergaard, Anne-Sophie, Berntsen, Marianne, Loft, Annika, Kjær, Andreas, Gerhart-Hines, Zachary, Johannesen, Helle H., Pedersen, Bente K., Karstoft, Kristian, Scheele, Camilla
Publicado 2021

Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling

por Khatib-Massalha, Eman, Bhattacharya, Suditi, Massalha, Hassan, Biram, Adi, Golan, Karin, Kollet, Orit, Kumari, Anju, Avemaria, Francesca, Petrovich-Kopitman, Ekaterina, Gur-Cohen, Shiri, Itkin, Tomer, Brandenburger, Isabell, Spiegel, Asaf, Shulman, Ziv, Gerhart-Hines, Zachary, Itzkovitz, Shalev, Gunzer, Matthias, Offermanns, Stefan, Alon, Ronen, Ariel, Amiram, Lapidot, Tsvee
Publicado 2020

Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis

por Johnson, Jordan M., Peterlin, Alek D., Balderas, Enrique, Sustarsic, Elahu G., Maschek, J. Alan, Lang, Marisa J., Jara-Ramos, Alejandro, Panic, Vanja, Morgan, Jeffrey T., Villanueva, Claudio J., Sanchez, Alejandro, Rutter, Jared, Lodhi, Irfan J., Cox, James E., Fisher-Wellman, Kelsey H., Chaudhuri, Dipayan, Gerhart-Hines, Zachary, Funai, Katsuhiko
Publicado 2023

TNIK is a conserved regulator of glucose and lipid metabolism in obesity

por Pham, T. C. Phung, Dollet, Lucile, Ali, Mona S., Raun, Steffen H., Møller, Lisbeth L. V., Jafari, Abbas, Ditzel, Nicholas, Andersen, Nicoline R., Fritzen, Andreas M., Gerhart-Hines, Zachary, Kiens, Bente, Suomalainen, Anu, Simpson, Stephen J., Salling Olsen, Morten, Kieser, Arnd, Schjerling, Peter, Nieminen, Anni I., Richter, Erik A., Havula, Essi, Sylow, Lykke
Publicado 2023

Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response

por Snieckute, Goda, Genzor, Aitana Victoria, Vind, Anna Constance, Ryder, Laura, Stoneley, Mark, Chamois, Sébastien, Dreos, René, Nordgaard, Cathrine, Sass, Frederike, Blasius, Melanie, López, Aida Rodríguez, Brynjólfsdóttir, Sólveig Hlín, Andersen, Kasper Langebjerg, Willis, Anne E., Frankel, Lisa B., Poulsen, Steen Seier, Gatfield, David, Gerhart-Hines, Zachary, Clemmensen, Christoffer, Bekker-Jensen, Simon
Publicado 2022

Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells

por Møller, Sofie H., Mellergaard, Maiken, Madsen, Mikkel, Bermejo, Amaia V., Jepsen, Stine D., Hansen, Marie H., Høgh, Rikke I., Aldana, Blanca I., Desler, Claus, Rasmussen, Lene Juel, Sustarsic, Elahu G., Gerhart-Hines, Zachary, Daskalaki, Evangelia, Wheelock, Craig E., Hiron, Thomas K., Lin, Da, O’Callaghan, Christopher A., Wandall, Hans H., Andresen, Lars, Skov, Søren
Publicado 2020

ADRA1A–Gα(q) signalling potentiates adipocyte thermogenesis through CKB and TNAP

por Rahbani, Janane F., Scholtes, Charlotte, Lagarde, Damien M., Hussain, Mohammed F., Roesler, Anna, Dykstra, Christien B., Bunk, Jakub, Samborska, Bozena, O’Brien, Shannon L., Tripp, Emma, Pacis, Alain, Angueira, Anthony R., Johansen, Olivia S., Cinkornpumin, Jessica, Hossain, Ishtiaque, Lynes, Matthew D., Zhang, Yang, White, Andrew P., Pastor, William A., Chondronikola, Maria, Sidossis, Labros, Klein, Samuel, Kralli, Anastasia, Cypess, Aaron M., Pedersen, Steen B., Jessen, Niels, Tseng, Yu-Hua, Gerhart-Hines, Zachary, Seale, Patrick, Calebiro, Davide, Giguère, Vincent, Kazak, Lawrence
Publicado 2022

Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

por Sustarsic, Elahu G., Ma, Tao, Lynes, Matthew D., Larsen, Michael, Karavaeva, Iuliia, Havelund, Jesper F., Nielsen, Carsten H., Jedrychowski, Mark P., Moreno-Torres, Marta, Lundh, Morten, Plucinska, Kaja, Jespersen, Naja Z., Grevengoed, Trisha J., Kramar, Barbara, Peics, Julia, Hansen, Jakob B., Shamsi, Farnaz, Forss, Isabel, Neess, Ditte, Keipert, Susanne, Wang, Jianing, Stohlmann, Katharina, Brandslund, Ivan, Christensen, Cramer, Jørgensen, Marit E., Linneberg, Allan, Pedersen, Oluf, Kiebish, Michael A., Qvortrup, Klaus, Han, Xianlin, Pedersen, Bente Klarlund, Jastroch, Martin, Mandrup, Susanne, Kjær, Andreas, Gygi, Steven P., Hansen, Torben, Gillum, Matthew P., Grarup, Niels, Emanuelli, Brice, Nielsen, Søren, Scheele, Camilla, Tseng, Yu-Hua, Færgeman, Nils J., Gerhart-Hines, Zachary
Publicado 2018

Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

por Sveidahl Johansen, Olivia, Ma, Tao, Hansen, Jakob Bondo, Markussen, Lasse Kruse, Schreiber, Renate, Reverte-Salisa, Laia, Dong, Hua, Christensen, Dan Ploug, Sun, Wenfei, Gnad, Thorsten, Karavaeva, Iuliia, Nielsen, Thomas Svava, Kooijman, Sander, Cero, Cheryl, Dmytriyeva, Oksana, Shen, Yachen, Razzoli, Maria, O’Brien, Shannon L., Kuipers, Eline N., Nielsen, Carsten Haagen, Orchard, William, Willemsen, Nienke, Jespersen, Naja Zenius, Lundh, Morten, Sustarsic, Elahu Gosney, Hallgren, Cecilie Mørch, Frost, Mikkel, McGonigle, Seth, Isidor, Marie Sophie, Broholm, Christa, Pedersen, Oluf, Hansen, Jacob Bo, Grarup, Niels, Hansen, Torben, Kjær, Andreas, Granneman, James G., Babu, M. Madan, Calebiro, Davide, Nielsen, Søren, Rydén, Mikael, Soccio, Raymond, Rensen, Patrick C.N., Treebak, Jonas Thue, Schwartz, Thue Walter, Emanuelli, Brice, Bartolomucci, Alessandro, Pfeifer, Alexander, Zechner, Rudolf, Scheele, Camilla, Mandrup, Susanne, Gerhart-Hines, Zachary
Publicado 2021