Glix 13, a New Drug Acting on Glutamatergic Pathways in Children and Animal Models of Autism Spectrum Disorders

por Santini, Annamaria Chiara, Pierantoni, Giovanna Maria, Gerlini, Raffaele, Iorio, Rosamaria, Olabinjo, Yinka, Giovane, Alfonso, Di Domenico, Marina, Sogos, Carla
Publicado 2014

Deregulation of HMGA1 expression induces chromosome instability through regulation of spindle assembly checkpoint genes

por Pierantoni, Giovanna Maria, Conte, Andrea, Rinaldo, Cinzia, Tornincasa, Mara, Gerlini, Raffaele, Federico, Antonella, Valente, Davide, Medico, Enzo, Fusco, Alfredo
Publicado 2015

High mobility group A1 protein modulates autophagy in cancer cells

por Conte, Andrea, Paladino, Simona, Bianco, Gaia, Fasano, Dominga, Gerlini, Raffaele, Tornincasa, Mara, Renna, Maurizio, Fusco, Alfredo, Tramontano, Donatella, Pierantoni, Giovanna Maria
Publicado 2017

Double knock-out of Hmga1 and Hipk2 genes causes perinatal death associated to respiratory distress and thyroid abnormalities in mice

por Gerlini, Raffaele, Amendola, Elena, Conte, Andrea, Valente, Valeria, Tornincasa, Mara, Credendino, Sara Carmela, Cammarota, Francesca, Gentile, Chiara, Di Guida, Luigi, Paladino, Simona, De Vita, Gabriella, Fusco, Alfredo, Pierantoni, Giovanna Maria
Publicado 2019

Mice lacking the mitochondrial exonuclease MGME1 develop inflammatory kidney disease with glomerular dysfunction

por Milenkovic, Dusanka, Sanz-Moreno, Adrián, Calzada-Wack, Julia, Rathkolb, Birgit, Veronica Amarie, Oana, Gerlini, Raffaele, Aguilar-Pimentel, Antonio, Misic, Jelena, Simard, Marie-Lune, Wolf, Eckhard, Fuchs, Helmut, Gailus-Durner, Valerie, de Angelis, Martin Hrabě, Larsson, Nils-Göran
Publicado 2022

Increased estrogen to androgen ratio enhances immunoglobulin levels and impairs B cell function in male mice

por Aguilar-Pimentel, Juan Antonio, Cho, Yi-Li, Gerlini, Raffaele, Calzada-Wack, Julia, Wimmer, Maria, Mayer-Kuckuk, Philipp, Adler, Thure, Schmidt-Weber, Carsten B., Busch, Dirk H., Fuchs, Helmut, Gailus-Durner, Valérie, Ollert, Markus, Hrabě de Angelis, Martin, Ohlsson, Claes, Poutanen, Matti, Teperino, Raffaele, Strauss, Leena
Publicado 2020

Disruption of paternal circadian rhythm affects metabolic health in male offspring via nongerm cell factors

por Lassi, Maximilian, Tomar, Archana, Comas-Armangué, Gemma, Vogtmann, Rebekka, Dijkstra, Dorieke J., Corujo, David, Gerlini, Raffaele, Darr, Jonatan, Scheid, Fabienne, Rozman, Jan, Aguilar-Pimentel, Antonio, Koren, Omry, Buschbeck, Marcus, Fuchs, Helmut, Marschall, Susan, Gailus-Durner, Valerie, Hrabe de Angelis, Martin, Plösch, Torsten, Gellhaus, Alexandra, Teperino, Raffaele
Publicado 2021

Identifying causal serum protein–cardiometabolic trait relationships using whole genome sequencing

por Png, Grace, Gerlini, Raffaele, Hatzikotoulas, Konstantinos, Barysenka, Andrei, Rayner, N William, Klarić, Lucija, Rathkolb, Birgit, Aguilar-Pimentel, Juan A, Rozman, Jan, Fuchs, Helmut, Gailus-Durner, Valerie, Tsafantakis, Emmanouil, Karaleftheri, Maria, Dedoussis, George, Pietrzik, Claus, Wilson, James F, de Angelis, Martin Hrabe, Becker-Pauly, Christoph, Gilly, Arthur, Zeggini, Eleftheria
Publicado 2022

Knockout mouse models as a resource for the study of rare diseases

por da Silva-Buttkus, Patricia, Spielmann, Nadine, Klein-Rodewald, Tanja, Schütt, Christine, Aguilar-Pimentel, Antonio, Amarie, Oana V., Becker, Lore, Calzada-Wack, Julia, Garrett, Lillian, Gerlini, Raffaele, Kraiger, Markus, Leuchtenberger, Stefanie, Östereicher, Manuela A., Rathkolb, Birgit, Sanz-Moreno, Adrián, Stöger, Claudia, Hölter, Sabine M., Seisenberger, Claudia, Marschall, Susan, Fuchs, Helmut, Gailus-Durner, Valerie, Hrabě de Angelis, Martin
Publicado 2023

Insights into energy balance dysregulation from a mouse model of methylmalonic aciduria

por Lucienne, Marie, Gerlini, Raffaele, Rathkolb, Birgit, Calzada-Wack, Julia, Forny, Patrick, Wueest, Stephan, Kaech, Andres, Traversi, Florian, Forny, Merima, Bürer, Céline, Aguilar-Pimentel, Antonio, Irmler, Martin, Beckers, Johannes, Sauer, Sven, Kölker, Stefan, Dewulf, Joseph P, Bommer, Guido T, Hoces, Daniel, Gailus-Durner, Valerie, Fuchs, Helmut, Rozman, Jan, Froese, D Sean, Baumgartner, Matthias R, de Angelis, Martin Hrabě
Publicado 2023

Post-synaptic scaffold protein TANC2 in psychiatric and somatic disease risk

por Garrett, Lillian, Da Silva-Buttkus, Patricia, Rathkolb, Birgit, Gerlini, Raffaele, Becker, Lore, Sanz-Moreno, Adrian, Seisenberger, Claudia, Zimprich, Annemarie, Aguilar-Pimentel, Antonio, Amarie, Oana V., Cho, Yi-Li, Kraiger, Markus, Spielmann, Nadine, Calzada-Wack, Julia, Marschall, Susan, Busch, Dirk, Schmitt-Weber, Carsten, Wolf, Eckhard, Wurst, Wolfgang, Fuchs, Helmut, Gailus-Durner, Valerie, Hölter, Sabine M., Hrabě de Angelis, Martin
Publicado 2022

Dietary intervention improves health metrics and life expectancy of the genetically obese Titan mouse

por Müller-Eigner, Annika, Sanz-Moreno, Adrián, de-Diego, Irene, Venkatasubramani, Anuroop Venkateswaran, Langhammer, Martina, Gerlini, Raffaele, Rathkolb, Birgit, Aguilar-Pimentel, Antonio, Klein-Rodewald, Tanja, Calzada-Wack, Julia, Becker, Lore, Palma-Vera, Sergio, Gille, Benedikt, Forne, Ignasi, Imhof, Axel, Meng, Chen, Ludwig, Christina, Koch, Franziska, Heiker, John T., Kuhla, Angela, Caton, Vanessa, Brenmoehl, Julia, Reyer, Henry, Schoen, Jennifer, Fuchs, Helmut, Gailus-Durner, Valerie, Hoeflich, Andreas, de Angelis, Martin Hrabe, Peleg, Shahaf
Publicado 2022

METTL6 is a tRNA m(3)C methyltransferase that regulates pluripotency and tumor cell growth

por Ignatova, Valentina V., Kaiser, Steffen, Ho, Jessica Sook Yuin, Bing, Xinyang, Stolz, Paul, Tan, Ying Xim, Lee, Chee Leng, Gay, Florence Pik Hoon, Lastres, Palma Rico, Gerlini, Raffaele, Rathkolb, Birgit, Aguilar-Pimentel, Antonio, Sanz-Moreno, Adrián, Klein-Rodewald, Tanja, Calzada-Wack, Julia, Ibragimov, Emil, Valenta, Magdalena, Lukauskas, Saulius, Pavesi, Andrea, Marschall, Susan, Leuchtenberger, Stefanie, Fuchs, Helmut, Gailus-Durner, Valerie, de Angelis, Martin Hrabe, Bultmann, Sebastian, Rando, Oliver J., Guccione, Ernesto, Kellner, Stefanie M., Schneider, Robert
Publicado 2020

Characterising a homozygous two‐exon deletion in UQCRH: comparing human and mouse phenotypes

por Vidali, Silvia, Gerlini, Raffaele, Thompson, Kyle, Urquhart, Jill E, Meisterknecht, Jana, Aguilar‐Pimentel, Juan Antonio, Amarie, Oana V, Becker, Lore, Breen, Catherine, Calzada‐Wack, Julia, Chhabra, Nirav F, Cho, Yi‐Li, da Silva‐Buttkus, Patricia, Feichtinger, René G, Gampe, Kristine, Garrett, Lillian, Hoefig, Kai P, Hölter, Sabine M, Jameson, Elisabeth, Klein‐Rodewald, Tanja, Leuchtenberger, Stefanie, Marschall, Susan, Mayer‐Kuckuk, Philipp, Miller, Gregor, Oestereicher, Manuela A, Pfannes, Kristina, Rathkolb, Birgit, Rozman, Jan, Sanders, Charlotte, Spielmann, Nadine, Stoeger, Claudia, Szibor, Marten, Treise, Irina, Walter, John H, Wurst, Wolfgang, Mayr, Johannes A, Fuchs, Helmut, Gärtner, Ulrich, Wittig, Ilka, Taylor, Robert W, Newman, William G, Prokisch, Holger, Gailus‐Durner, Valerie, Hrabě de Angelis, Martin
Publicado 2021

Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice

por Xie, Kan, Fuchs, Helmut, Scifo, Enzo, Liu, Dan, Aziz, Ahmad, Aguilar-Pimentel, Juan Antonio, Amarie, Oana Veronica, Becker, Lore, da Silva-Buttkus, Patricia, Calzada-Wack, Julia, Cho, Yi-Li, Deng, Yushuang, Edwards, A. Cole, Garrett, Lillian, Georgopoulou, Christina, Gerlini, Raffaele, Hölter, Sabine M., Klein-Rodewald, Tanja, Kramer, Michael, Leuchtenberger, Stefanie, Lountzi, Dimitra, Mayer-Kuckuk, Phillip, Nover, Lena L., Oestereicher, Manuela A., Overkott, Clemens, Pearson, Brandon L., Rathkolb, Birgit, Rozman, Jan, Russ, Jenny, Schaaf, Kristina, Spielmann, Nadine, Sanz-Moreno, Adrián, Stoeger, Claudia, Treise, Irina, Bano, Daniele, Busch, Dirk H., Graw, Jochen, Klingenspor, Martin, Klopstock, Thomas, Mock, Beverly A., Salomoni, Paolo, Schmidt-Weber, Carsten, Weiergräber, Marco, Wolf, Eckhard, Wurst, Wolfgang, Gailus-Durner, Valérie, Breteler, Monique M. B., Hrabě de Angelis, Martin, Ehninger, Dan
Publicado 2022