Application of the Co-Agonist Concerted Transition Model to Analysis of GABA(A) Receptor Properties

por Germann, Allison L., Steinbach, Joe Henry, Akk, Gustav
Publicado 2019

Activation of the α1β2γ2L GABA(A) Receptor by Physiological Agonists

por Pierce, Spencer R., Germann, Allison L., Akk, Gustav
Publicado 2021

Steady-state activation of the high-affinity isoform of the α4β2δ GABA(A) receptor

por Pierce, Spencer R., Senneff, Thomas C., Germann, Allison L., Akk, Gustav
Publicado 2019

Activation of the Rat α1β2ε GABA(A) Receptor by Orthosteric and Allosteric Agonists

por Germann, Allison L., Burbridge, Ariel B., Pierce, Spencer R., Akk, Gustav
Publicado 2022

Perspective on the Relationship between GABA(A) Receptor Activity and the Apparent Potency of an Inhibitor

por Germann, Allison L., Pierce, Spencer R., Evers, Alex S., Steinbach, Joe Henry, Akk, Gustav
Publicado 2022

Steady‐state activation and modulation of the synaptic‐type α1β2γ2L GABA(A) receptor by combinations of physiological and clinical ligands

por Germann, Allison L., Pierce, Spencer R., Senneff, Thomas C., Burbridge, Ariel B., Steinbach, Joe Henry, Akk, Gustav
Publicado 2019

Mutational Analysis of Anesthetic Binding Sites and Their Effects on GABA(A) Receptor Activation and Modulation by Positive Allosteric Modulators of the α7 Nicotinic Receptor

por Pierce, Spencer R., Germann, Allison L., Xu, Sophia Q., Menon, Saumith L., Ortells, Marcelo O., Arias, Hugo R., Akk, Gustav
Publicado 2023

Enhanced GABAergic actions resulting from the coapplication of the steroid 3α-hydroxy-5α-pregnane-11,20-dione (alfaxalone) with propofol or diazepam

por Cao, Lily Q., Montana, Michael C., Germann, Allison L., Shin, Daniel J., Chakrabarti, Sampurna, Mennerick, Steven, Yuede, Carla M., Wozniak, David F., Evers, Alex S., Akk, Gustav
Publicado 2018

The Mechanism of Enantioselective Neurosteroid Actions on GABA(A) Receptors

por Tateiwa, Hiroki, Chintala, Satyanarayana M., Chen, Ziwei, Wang, Lei, Amtashar, Fatima, Bracamontes, John, Germann, Allison L., Pierce, Spencer R., Covey, Douglas F., Akk, Gustav, Evers, Alex S.
Publicado 2023

UNC-49 is a redox-sensitive GABA(A) receptor that regulates the mitochondrial unfolded protein response cell nonautonomously

por Pohl, Franziska, Germann, Allison L., Mao, Jack, Hou, Sydney, Bakare, Bayode, Kong Thoo Lin, Paul, Yates, Kyari, Nonet, Michael L., Akk, Gustav, Kornfeld, Kerry, Held, Jason M.
Publicado 2023

Nicotine Dependence is Associated with Functional Variation in FMO3, an Enzyme that Metabolizes Nicotine in the Brain

por Teitelbaum, Aaron M., Murphy, Sharon E., Akk, Gustav, Baker, Timothy B., Germann, Allison, von Weymarn, Linda B., Bierut, Laura J., Goate, Alison, Kharasch, Evan D., Bloom, A. Joseph
Publicado 2017

Multiple Non-Equivalent Interfaces Mediate Direct Activation of GABA(A) Receptors by Propofol

por Eaton, Megan M., Germann, Allison L., Arora, Ruby, Cao, Lily Q., Gao, Xiaoyi, Shin, Daniel J., Wu, Albert, Chiara, David C., Cohen, Jonathan B., Steinbach, Joe Henry, Evers, Alex S., Akk, Gustav
Publicado 2016

Site-specific effects of neurosteroids on GABA(A) receptor activation and desensitization

por Sugasawa, Yusuke, Cheng, Wayland WL, Bracamontes, John R, Chen, Zi-Wei, Wang, Lei, Germann, Allison L, Pierce, Spencer R, Senneff, Thomas C, Krishnan, Kathiresan, Reichert, David E, Covey, Douglas F, Akk, Gustav, Evers, Alex S
Publicado 2020

Multiple functional neurosteroid binding sites on GABA(A) receptors

por Chen, Zi-Wei, Bracamontes, John R., Budelier, Melissa M., Germann, Allison L., Shin, Daniel J., Kathiresan, Krishnan, Qian, Ming-Xing, Manion, Brad, Cheng, Wayland W. L., Reichert, David E., Akk, Gustav, Covey, Douglas F., Evers, Alex S.
Publicado 2019