IL-6 pathway-driven investigation of response to IL-6 receptor inhibition in rheumatoid arthritis

por Wang, Jianmei, Platt, Adam, Upmanyu, Ruchi, Germer, Søren, Lei, Guiyuan, Rabe, Christina, Benayed, Ryma, Kenwright, Andrew, Hemmings, Andrew, Martin, Mitchell, Harari, Olivier
Publicado 2013

Whole-genome bisulfite sequencing with improved accuracy and cost

por Suzuki, Masako, Liao, Will, Wos, Frank, Johnston, Andrew D., DeGrazia, Justin, Ishii, Jennifer, Bloom, Toby, Zody, Michael C., Germer, Soren, Greally, John M.
Publicado 2018

Features of Circulating Parainfluenza Virus Required for Growth in Human Airway

por Palermo, Laura M., Uppal, Manik, Skrabanek, Lucy, Zumbo, Paul, Germer, Soren, Toussaint, Nora C., Rima, Bert K., Huey, Devra, Niewiesk, Stefan, Porotto, Matteo, Moscona, Anne
Publicado 2016

Deep whole-genome sequencing of 3 cancer cell lines on 2 sequencing platforms

por Arora, Kanika, Shah, Minita, Johnson, Molly, Sanghvi, Rashesh, Shelton, Jennifer, Nagulapalli, Kshithija, Oschwald, Dayna M., Zody, Michael C., Germer, Soren, Jobanputra, Vaidehi, Carter, Jade, Robine, Nicolas
Publicado 2019

Interaction Effect of Genetic Polymorphisms in Glucokinase (GCK) and Glucokinase Regulatory Protein (GCKR) on Metabolic Traits in Healthy Chinese Adults and Adolescents

por Tam, Claudia H.T., Ma, Ronald C.W., So, Wing Yee, Wang, Ying, Lam, Vincent K.L., Germer, Soren, Martin, Mitchell, Chan, Juliana C.N., Ng, Maggie C.Y.
Publicado 2009

Disease variants in genomes of 44 centenarians

por Freudenberg-Hua, Yun, Freudenberg, Jan, Vacic, Vladimir, Abhyankar, Avinash, Emde, Anne-Katrin, Ben-Avraham, Danny, Barzilai, Nir, Oschwald, Dayna, Christen, Erika, Koppel, Jeremy, Greenwald, Blaine, Darnell, Robert B, Germer, Soren, Atzmon, Gil, Davies, Peter
Publicado 2014

Common Polymorphisms in MTNR1B, G6PC2 and GCK Are Associated with Increased Fasting Plasma Glucose and Impaired Beta-Cell Function in Chinese Subjects

por Tam, Claudia Ha Ting, Ho, Janice Sin Ka, Wang, Ying, Lee, Heung Man, Lam, Vincent Kwok Lim, Germer, Soren, Martin, Mitchell, So, Wing Yee, Ma, Ronald Ching Wan, Chan, Juliana Chung Ngor, Ng, Maggie Chor Yin
Publicado 2010

High-coverage whole-genome sequencing of the expanded 1000 Genomes Project cohort including 602 trios

por Byrska-Bishop, Marta, Evani, Uday S., Zhao, Xuefang, Basile, Anna O., Abel, Haley J., Regier, Allison A., Corvelo, André, Clarke, Wayne E., Musunuri, Rajeeva, Nagulapalli, Kshithija, Fairley, Susan, Runnels, Alexi, Winterkorn, Lara, Lowy, Ernesto, Paul Flicek, Germer, Soren, Brand, Harrison, Hall, Ira M., Talkowski, Michael E., Narzisi, Giuseppe, Zody, Michael C.
Publicado 2022

Postvaccination SARS-COV-2 among Health Care Workers in New Jersey: A Genomic Epidemiological Study

por Mathema, Barun, Chen, Liang, Chow, Kar Fai, Zhao, Yanan, Zody, Michael C., Mediavilla, Jose R., Cunningham, Marcus H., Composto, Kaelea, Lee, Annie, Oschwald, Dayna M., Germer, Soren, Fennessey, Samantha, Patel, Kishan, Wilson, David, Cassell, Ann, Pascual, Lauren, Ip, Andrew, Corvelo, André, Dar, Sophia, Kramer, Yael, Maniatis, Tom, Perlin, David S., Kreiswirth, Barry N.
Publicado 2021

Emergence of Multiple SARS-CoV-2 Antibody Escape Variants in an Immunocompromised Host Undergoing Convalescent Plasma Treatment

por Chen, Liang, Zody, Michael C., Di Germanio, Clara, Martinelli, Rachel, Mediavilla, Jose R., Cunningham, Marcus H., Composto, Kaelea, Chow, Kar Fai, Kordalewska, Milena, Corvelo, André, Oschwald, Dayna M., Fennessey, Samantha, Zetkulic, Marygrace, Dar, Sophia, Kramer, Yael, Mathema, Barun, Germer, Soren, Stone, Mars, Simmons, Graham, Busch, Michael P., Maniatis, Tom, Perlin, David S., Kreiswirth, Barry N.
Publicado 2021

YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics

por Fan, Pang-Dian, Narzisi, Giuseppe, Jayaprakash, Anitha D., Venturini, Elisa, Robine, Nicolas, Smibert, Peter, Germer, Soren, Yu, Helena A., Jordan, Emmet J., Paik, Paul K., Janjigian, Yelena Y., Chaft, Jamie E., Wang, Lu, Jungbluth, Achim A., Middha, Sumit, Spraggon, Lee, Qiao, Huan, Lovly, Christine M., Kris, Mark G., Riely, Gregory J., Politi, Katerina, Varmus, Harold, Ladanyi, Marc
Publicado 2018

Genomic Epidemiology and Serology Associated with a SARS-CoV-2 R.1 Variant Outbreak in New Jersey

por Mathema, Barun, Chen, Liang, Wang, Pengfei, Cunningham, Marcus H., Mediavilla, Jose R., Chow, Kar Fai, Luo, Yang, Zhao, Yanan, Composto, Kaelea, Zuckerman, Jerry, Zody, Michael C., Wilson, Nancy, Lee, Annie, Oschwald, Dayna M., Liu, Lihong, Iketani, Sho, Germer, Soren, Fennessey, Samantha, Wang, Maple, Kramer, Yael, Toole, Patricia, Maniatis, Tom, Ho, David D., Perlin, David S., Kreiswirth, Barry N.
Publicado 2022

Accounting for population structure in genetic studies of cystic fibrosis

por Kingston, Hanley, Stilp, Adrienne M., Gordon, William, Broome, Jai, Gogarten, Stephanie M., Ling, Hua, Barnard, John, Dugan-Perez, Shannon, Ellinor, Patrick T., Gabriel, Stacey, Germer, Soren, Gibbs, Richard A., Gupta, Namrata, Rice, Kenneth, Smith, Albert V., Zody, Michael C., Blackman, Scott M., Cutting, Garry, Knowles, Michael R., Zhou, Yi-Hui, Rosenfeld, Margaret, Gibson, Ronald L., Bamshad, Michael, Fohner, Alison, Blue, Elizabeth E.
Publicado 2022

Nasal airway transcriptome-wide association study of asthma reveals genetically driven mucus pathobiology

por Sajuthi, Satria P., Everman, Jamie L., Jackson, Nathan D., Saef, Benjamin, Rios, Cydney L., Moore, Camille M., Mak, Angel C. Y., Eng, Celeste, Fairbanks-Mahnke, Ana, Salazar, Sandra, Elhawary, Jennifer, Huntsman, Scott, Medina, Vivian, Nickerson, Deborah A., Germer, Soren, Zody, Michael C., Abecasis, Gonçalo, Kang, Hyun Min, Rice, Kenneth M., Kumar, Rajesh, Zaitlen, Noah A., Oh, Sam, Rodríguez-Santana, José, Burchard, Esteban G., Seibold, Max A.
Publicado 2022

Author Correction: Nasal airway transcriptome-wide association study of asthma reveals genetically driven mucus pathobiology

por Sajuthi, Satria P., Everman, Jamie L., Jackson, Nathan D., Saef, Benjamin, Rios, Cydney L., Moore, Camille M., Mak, Angel C. Y., Eng, Celeste, Fairbanks–Mahnke, Ana, Salazar, Sandra, Elhawary, Jennifer, Huntsman, Scott, Medina, Vivian, Nickerson, Deborah A., Germer, Soren, Zody, Michael C., Abecasis, Gonçalo, Kang, Hyun Min, Rice, Kenneth M., Kumar, Rajesh, Zaitlen, Noah A., Oh, Sam, Rodríguez–Santana, José, Burchard, Esteban G., Seibold, Max A.
Publicado 2022

Type 2 and interferon inflammation strongly regulate SARS-CoV-2 related gene expression in the airway epithelium

por Sajuthi, Satria P., DeFord, Peter, Jackson, Nathan D., Montgomery, Michael T., Everman, Jamie L., Rios, Cydney L., Pruesse, Elmar, Nolin, James D., Plender, Elizabeth G., Wechsler, Michael E., Mak, Angel CY, Eng, Celeste, Salazar, Sandra, Medina, Vivian, Wohlford, Eric M., Huntsman, Scott, Nickerson, Deborah A., Germer, Soren, Zody, Michael C., Abecasis, Gonçalo, Kang, Hyun Min, Rice, Kenneth M., Kumar, Rajesh, Oh, Sam, Rodriguez-Santana, Jose, Burchard, Esteban G., Seibold, Max A.
Publicado 2020

Asthma and its relationship to mitochondrial copy number: Results from the Asthma Translational Genomics Collaborative (ATGC) of the Trans-Omics for Precision Medicine (TOPMed) pro...

por Cocco, Maxwell P., White, Evan, Xiao, Shujie, Hu, Donglei, Mak, Angel, Sleiman, Patrick, Yang, Mao, Bobbitt, Kevin R., Gui, Hongsheng, Levin, Albert M., Hochstadt, Samantha, Whitehouse, Kyle, Rynkowski, Dean, Barczak, Andrea J., Abecasis, Gonçalo, Blackwell, Thomas W., Kang, Hyun Min, Nickerson, Deborah A., Germer, Soren, Ding, Jun, Lanfear, David E., Gilliland, Frank, Gauderman, W. James, Kumar, Rajesh, Erle, David J., Martinez, Fernando, Hakonarson, Hakon, Burchard, Esteban G., Williams, L. Keoki
Publicado 2020

Type 2 and interferon inflammation regulate SARS-CoV-2 entry factor expression in the airway epithelium

por Sajuthi, Satria P., DeFord, Peter, Li, Yingchun, Jackson, Nathan D., Montgomery, Michael T., Everman, Jamie L., Rios, Cydney L., Pruesse, Elmar, Nolin, James D., Plender, Elizabeth G., Wechsler, Michael E., Mak, Angel C. Y., Eng, Celeste, Salazar, Sandra, Medina, Vivian, Wohlford, Eric M., Huntsman, Scott, Nickerson, Deborah A., Germer, Soren, Zody, Michael C., Abecasis, Gonçalo, Kang, Hyun Min, Rice, Kenneth M., Kumar, Rajesh, Oh, Sam, Rodriguez-Santana, Jose, Burchard, Esteban G., Seibold, Max A.
Publicado 2020

Genetic control of mRNA splicing as a potential mechanism for incomplete penetrance of rare coding variants

por Einson, Jonah, Glinos, Dafni, Boerwinkle, Eric, Castaldi, Peter, Darbar, Dawood, de Andrade, Mariza, Ellinor, Patrick, Fornage, Myriam, Gabriel, Stacey, Germer, Soren, Gibbs, Richard, Hersh, Craig P., Johnsen, Jill, Kaplan, Robert, Konkle, Barbara A., Kooperberg, Charles, Nassir, Rami, Loos, Ruth J.F., Meyers, Deborah A, Mitchell, Braxton D., Psaty, Bruce, Vasan, Ramachandran S., Rich, Stephen S., Rienstra, Michael, Rotter, Jerome I., Saferali, Aabida, Shoemaker, M. Benjamin, Silverman, Edwin, Smith, Albert Vernon, Mohammadi, Pejman, Castel, Stephane E., Iossifov, Ivan, Lappalainen, Tuuli
Publicado 2023

Lung Function in African American Children with Asthma Is Associated with Novel Regulatory Variants of the KIT Ligand KITLG/SCF and Gene-By-Air-Pollution Interaction

por Mak, Angel C. Y., Sajuthi, Satria, Joo, Jaehyun, Xiao, Shujie, Sleiman, Patrick M., White, Marquitta J., Lee, Eunice Y., Saef, Benjamin, Hu, Donglei, Gui, Hongsheng, Keys, Kevin L., Lurmann, Fred, Jain, Deepti, Abecasis, Gonçalo, Kang, Hyun Min, Nickerson, Deborah A., Germer, Soren, Zody, Michael C., Winterkorn, Lara, Reeves, Catherine, Huntsman, Scott, Eng, Celeste, Salazar, Sandra, Oh, Sam S., Gilliland, Frank D., Chen, Zhanghua, Kumar, Rajesh, Martínez, Fernando D., Wu, Ann Chen, Ziv, Elad, Hakonarson, Hakon, Himes, Blanca E., Williams, L. Keoki, Seibold, Max A., Burchard, Esteban G.
Publicado 2020