Targeted genome and epigenome editing using engineered TALE and CRISPR/Cas9 technologies

por Gersbach, Charles A
Publicado 2014

Pulling the genome in opposite directions to dissect gene networks

por Gersbach, Charles A., Barrangou, Rodolphe
Publicado 2018

The once and future gene therapy

por Bulaklak, Karen, Gersbach, Charles A.
Publicado 2020

Light-Inducible Spatiotemporal Control of Gene Activation by Customizable Zinc Finger Transcription Factors

por Polstein, Lauren R., Gersbach, Charles A.
Publicado 2012

A light-inducible CRISPR/Cas9 system for control of endogenous gene activation

por Polstein, Lauren R., Gersbach, Charles A.
Publicado 2015

Enabling functional genomics with genome engineering

por Hilton, Isaac B., Gersbach, Charles A.
Publicado 2015

Genome editing: the end of the beginning

por Doudna, Jennifer A., Gersbach, Charles A.
Publicado 2015

Genome-editing Technologies for Gene and Cell Therapy

por Maeder, Morgan L, Gersbach, Charles A
Publicado 2016

Synthetic Zinc Finger Proteins: The Advent of Targeted Gene Regulation and Genome Modification Technologies

por Gersbach, Charles A., Gaj, Thomas, Barbas, Carlos F.
Publicado 2014

Directed evolution of recombinase specificity by split gene reassembly

por Gersbach, Charles A., Gaj, Thomas, Gordley, Russell M., Barbas, Carlos F.
Publicado 2010

Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases

por Perez-Pinera, Pablo, Ousterout, David G., Brown, Matthew T., Gersbach, Charles A.
Publicado 2012

Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector

por Kabadi, Ami M., Ousterout, David G., Hilton, Isaac B., Gersbach, Charles A.
Publicado 2014

Vector modifications to eliminate transposase expression following piggyBac-mediated transgenesis

por Chakraborty, Syandan, Ji, HaYeun, Chen, Jack, Gersbach, Charles A., Leong, Kam W.
Publicado 2014

Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs

por Brunger, Jonathan M., Zutshi, Ananya, Willard, Vincent P., Gersbach, Charles A., Guilak, Farshid
Publicado 2017

Targeted plasmid integration into the human genome by an engineered zinc-finger recombinase

por Gersbach, Charles A., Gaj, Thomas, Gordley, Russell M., Mercer, Andrew C., Barbas, Carlos F.
Publicado 2011

Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter

por Dicks, Amanda, Wu, Chia-Lung, Steward, Nancy, Adkar, Shaunak S., Gersbach, Charles A., Guilak, Farshid
Publicado 2020

Myogenic Progenitor Cell Lineage Specification by CRISPR/Cas9-Based Transcriptional Activators

por Kwon, Jennifer B., Vankara, Ashish, Ettyreddy, Adarsh R., Bohning, Joel D., Gersbach, Charles A.
Publicado 2020

A CRISPR/Cas9-Based System for Reprogramming Cell Lineage Specification

por Chakraborty, Syandan, Ji, HaYeun, Kabadi, Ami M., Gersbach, Charles A., Christoforou, Nicolas, Leong, Kam W.
Publicado 2014

Increasing the specificity of CRISPR systems with engineered RNA secondary structures

por Kocak, D. Dewran, Josephs, Eric A., Bhandarkar, Vidit, Adkar, Shaunak S., Kwon, Jennifer B., Gersbach, Charles A.
Publicado 2019

Multiplex CRISPR/Cas9-Based Genome Editing for Correction of Dystrophin Mutations that Cause Duchenne Muscular Dystrophy

por Ousterout, David G., Kabadi, Ami M., Thakore, Pratiksha I., Majoros, William H., Reddy, Timothy E., Gersbach, Charles A.
Publicado 2015