The Organoid Platform: Promises and Challenges as Tools in the Fight against COVID-19

por Geurts, Maarten H., van der Vaart, Jelte, Beumer, Joep, Clevers, Hans
Publicado 2021

Differentiation and CRISPR-Cas9-mediated genetic engineering of human intestinal organoids

por Martinez-Silgado, Adriana, Yousef Yengej, Fjodor A., Puschhof, Jens, Geurts, Veerle, Boot, Charelle, Geurts, Maarten H., Rookmaaker, Maarten B., Verhaar, Marianne C., Beumer, Joep, Clevers, Hans
Publicado 2022

Evolved Cas9 variants with broad PAM compatibility and high DNA specificity

por Hu, Johnny H., Miller, Shannon M., Geurts, Maarten H., Tang, Weixin, Chen, Liwei, Sun, Ning, Zeina, Christina M., Gao, Xue, Rees, Holly A., Lin, Zhi, Liu, David R.
Publicado 2018

Evaluating CRISPR-based prime editing for cancer modeling and CFTR repair in organoids

por Geurts, Maarten H, de Poel, Eyleen, Pleguezuelos-Manzano, Cayetano, Oka, Rurika, Carrillo, Léo, Andersson-Rolf, Amanda, Boretto, Matteo, Brunsveld, Jesse E, van Boxtel, Ruben, Beekman, Jeffrey M, Clevers, Hans
Publicado 2021

Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis

por Hendriks, Delilah, Brouwers, Jos F., Hamer, Karien, Geurts, Maarten H., Luciana, Léa, Massalini, Simone, López-Iglesias, Carmen, Peters, Peter J., Rodríguez-Colman, Maria J., Chuva de Sousa Lopes, Susana, Artegiani, Benedetta, Clevers, Hans
Publicado 2023

Modelling of primary ciliary dyskinesia using patient‐derived airway organoids

por van der Vaart, Jelte, Böttinger, Lena, Geurts, Maarten H, van de Wetering, Willine J, Knoops, Kèvin, Sachs, Norman, Begthel, Harry, Korving, Jeroen, Lopez‐Iglesias, Carmen, Peters, Peter J, Eitan, Kerem, Gileles‐Hillel, Alex, Clevers, Hans
Publicado 2021

A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses

por Beumer, Joep, Geurts, Maarten H., Lamers, Mart M., Puschhof, Jens, Zhang, Jingshu, van der Vaart, Jelte, Mykytyn, Anna Z., Breugem, Tim I., Riesebosch, Samra, Schipper, Debby, van den Doel, Petra B., de Lau, Wim, Pleguezuelos-Manzano, Cayetano, Busslinger, Georg, Haagmans, Bart L., Clevers, Hans
Publicado 2021

One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids

por Geurts, Maarten H., Gandhi, Shashank, Boretto, Matteo G., Akkerman, Ninouk, Derks, Lucca L. M., van Son, Gijs, Celotti, Martina, Harshuk-Shabso, Sarina, Peci, Flavia, Begthel, Harry, Hendriks, Delilah, Schürmann, Paul, Andersson-Rolf, Amanda, Chuva de Sousa Lopes, Susana M., van Es, Johan H., van Boxtel, Ruben, Clevers, Hans
Publicado 2023

Nanoblades allow high-level genome editing in murine and human organoids

por Tiroille, Victor, Krug, Adrien, Bokobza, Emma, Kahi, Michel, Bulcaen, Mattijs, Ensinck, Marjolein M., Geurts, Maarten H., Hendriks, Delilah, Vermeulen, François, Larbret, Frédéric, Gutierrez-Guerrero, Alejandra, Chen, Yu, Van Zundert, Indra, Rocha, Susana, Rios, Anne C., Medaer, Louise, Gijsbers, Rik, Mangeot, Philippe E., Clevers, Hans, Carlon, Marianne S., Bost, Frédéric, Verhoeyen, Els
Publicado 2023

Rapid tissue prototyping with micro-organospheres

por Wang, Zhaohui, Boretto, Matteo, Millen, Rosemary, Natesh, Naveen, Reckzeh, Elena S., Hsu, Carolyn, Negrete, Marcos, Yao, Haipei, Quayle, William, Heaton, Brook E., Harding, Alfred T., Bose, Shree, Driehuis, Else, Beumer, Joep, Rivera, Grecia O., van Ineveld, Ravian L., Gex, Donald, DeVilla, Jessica, Wang, Daisong, Puschhof, Jens, Geurts, Maarten H., Yeung, Athena, Hamele, Cait, Smith, Amber, Bankaitis, Eric, Xiang, Kun, Ding, Shengli, Nelson, Daniel, Delubac, Daniel, Rios, Anne, Abi-Hachem, Ralph, Jang, David, Goldstein, Bradley J., Glass, Carolyn, Heaton, Nicholas S., Hsu, David, Clevers, Hans, Shen, Xiling
Publicado 2022

Uncovering the mode of action of engineered T cells in patient cancer organoids

por Dekkers, Johanna F., Alieva, Maria, Cleven, Astrid, Keramati, Farid, Wezenaar, Amber K. L., van Vliet, Esmée J., Puschhof, Jens, Brazda, Peter, Johanna, Inez, Meringa, Angelo D., Rebel, Heggert G., Buchholz, Maj-Britt, Barrera Román, Mario, Zeeman, Amber L., de Blank, Sam, Fasci, Domenico, Geurts, Maarten H., Cornel, Annelisa M., Driehuis, Else, Millen, Rosemary, Straetemans, Trudy, Nicolasen, Mara J. T., Aarts-Riemens, Tineke, Ariese, Hendrikus C. R., Johnson, Hannah R., van Ineveld, Ravian L., Karaiskaki, Froso, Kopper, Oded, Bar-Ephraim, Yotam E., Kretzschmar, Kai, Eggermont, Alexander M. M., Nierkens, Stefan, Wehrens, Ellen J., Stunnenberg, Henk G., Clevers, Hans, Kuball, Jürgen, Sebestyen, Zsolt, Rios, Anne C.
Publicado 2022