Prevalence of type-1 interferon autoantibodies in adults with non-COVID-19 acute respiratory failure

por Ghale, Rajani, Spottiswoode, Natasha, Anderson, Mark S., Mitchell, Anthea, Wang, Grace, Calfee, Carolyn S., DeRisi, Joseph L., Langelier, Charles R.
Publicado 2022

Metagenomic prediction of antimicrobial resistance in critically ill patients with lower respiratory tract infections

por Serpa, Paula Hayakawa, Deng, Xianding, Abdelghany, Mazin, Crawford, Emily, Malcolm, Katherine, Caldera, Saharai, Fung, Monica, McGeever, Aaron, Kalantar, Katrina L., Lyden, Amy, Ghale, Rajani, Deiss, Thomas, Neff, Norma, Miller, Steven A., Doernberg, Sarah B., Chiu, Charles Y., DeRisi, Joseph L., Calfee, Carolyn S., Langelier, Charles R.
Publicado 2022

Plasma SARS-CoV-2 nucleocapsid antigen levels are associated with progression to severe disease in hospitalized COVID-19

por Wick, Katherine D., Leligdowicz, Aleksandra, Willmore, Andrew, Carrillo, Sidney A., Ghale, Rajani, Jauregui, Alejandra, Chak, Suzanna S., Nguyen, Viet, Lee, Deanna, Jones, Chayse, Dewar, Robin, Lane, H. Clifford, Kangelaris, Kirsten N., Hendrickson, Carolyn M., Liu, Kathleen D., Sinha, Pratik, Erle, David J., Langelier, Charles R., Krummell, Matthew F., Woodruff, Prescott G., Calfee, Carolyn S., Matthay, Michael A.
Publicado 2022

Integrated host-microbe plasma metagenomics for sepsis diagnosis in a prospective cohort of critically ill adults

por Kalantar, Katrina L., Neyton, Lucile, Abdelghany, Mazin, Mick, Eran, Jauregui, Alejandra, Caldera, Saharai, Serpa, Paula Hayakawa, Ghale, Rajani, Albright, Jack, Sarma, Aartik, Tsitsiklis, Alexandra, Leligdowicz, Aleksandra, Christenson, Stephanie A., Liu, Kathleen, Kangelaris, Kirsten N., Hendrickson, Carolyn, Sinha, Pratik, Gomez, Antonio, Neff, Norma, Pisco, Angela, Doernberg, Sarah B., Derisi, Joseph L., Matthay, Michael A., Calfee, Carolyn S., Langelier, Charles R.
Publicado 2022

COVID-19 ARDS is characterized by a dysregulated host response that differs from cytokine storm and is modified by dexamethasone

por Sarma, Aartik, Christenson, Stephanie A., Mick, Eran, DeVoe, Catherine, Deiss, Thomas, Pisco, Angela Oliveira, Ghale, Rajani, Jauregui, Alejandra, Byrne, Ashley, Moazed, Farzad, Spottiswoode, Natasha, Sinha, Pratik, Zha, Beth Shoshana, Neff, Norma, Tan, Michelle, Serpa, Paula Hayakawa, Ansel, K. Mark, Wilson, Jennifer G., Leligdowicz, Aleksandra, Siegel, Emily R., Sirota, Marina, DeRisi, Joseph L., Matthay, Michael A., Hendrickson, Carolyn M., Kangelaris, Kirsten N., Krummel, Matthew F., Woodruff, Prescott G., Erle, David J., Calfee, Carolyn S., Langelier, Charles R.
Publicado 2021

Impaired immune signaling and changes in the lung microbiome precede secondary bacterial pneumonia in COVID-19

por Tsitsiklis, Alexandra, Zha, Beth Shoshana, Byrne, Ashley, Devoe, Catherine, Levan, Sophia, Rackaityte, Elze, Sunshine, Sara, Mick, Eran, Ghale, Rajani, Jauregui, Alejandra, Sarma, Aartik, Neff, Norma, Serpa, Paula Hayakawa, Deiss, Thomas J., Kistler, Amy, Carrillo, Sidney, Ansel, K. Mark, Leligdowicz, Aleksandra, Christenson, Stephanie, Jones, Norman, Wu, Bing, Darmanis, Spyros, Matthay, Michael A., Lynch, Susan V., DeRisi, Joseph L., Hendrickson, Carolyn M., Kangelaris, Kirsten N., Krummel, Matthew F., Woodruff, Prescott G., Erle, David J., Rosenberg, Oren, Calfee, Carolyn S., Langelier, Charles R.
Publicado 2021

Tracheal aspirate RNA sequencing identifies distinct immunological features of COVID-19 ARDS

por Sarma, Aartik, Christenson, Stephanie A., Byrne, Ashley, Mick, Eran, Pisco, Angela Oliveira, DeVoe, Catherine, Deiss, Thomas, Ghale, Rajani, Zha, Beth Shoshana, Tsitsiklis, Alexandra, Jauregui, Alejandra, Moazed, Farzad, Detweiler, Angela M., Spottiswoode, Natasha, Sinha, Pratik, Neff, Norma, Tan, Michelle, Serpa, Paula Hayakawa, Willmore, Andrew, Ansel, K. Mark, Wilson, Jennifer G., Leligdowicz, Aleksandra, Siegel, Emily R., Sirota, Marina, DeRisi, Joseph L., Matthay, Michael A., Hendrickson, Carolyn M., Kangelaris, Kirsten N., Krummel, Matthew F., Woodruff, Prescott G., Erle, David J., Calfee, Carolyn S., Langelier, Charles R.
Publicado 2021

A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling

por Hackney, Jason A., Shivram, Haridha, Vander Heiden, Jason, Overall, Chris, Orozco, Luz, Gao, Xia, Kim, Eugene, West, Nathan, Qamra, Aditi, Chang, Diana, Chakrabarti, Arindam, Choy, David F., Combes, Alexis J., Courau, Tristan, Fragiadakis, Gabriela K., Rao, Arjun Arkal, Ray, Arja, Tsui, Jessica, Hu, Kenneth, Kuhn, Nicholas F., Krummel, Matthew F., Erle, David J., Kangelaris, Kirsten, Sarma, Aartik, Lyon, Zoe, Calfee, Carolyn S., Woodruff, Prescott G., Ghale, Rajani, Mick, Eran, Byrne, Ashley, Zha, Beth Shoshana, Langelier, Charles, Hendrickson, Carolyn M., van der Wijst, Monique G.P., Hartoularos, George C., Grant, Tianna, Bueno, Raymund, Lee, David S., Greenland, John R., Sun, Yang, Perez, Richard, Ogorodnikov, Anton, Ward, Alyssa, Ye, Chun Jimmie, Ramalingam, Thiru, McBride, Jacqueline M., Cai, Fang, Teterina, Anastasia, Bao, Min, Tsai, Larry, Rosas, Ivan O., Regev, Aviv, Kapadia, Sharookh B., Bauer, Rebecca N., Rosenberger, Carrie M.
Publicado 2023