Integrative analysis reveals RNA G-quadruplexes in UTRs are selectively constrained and enriched for functional associations

por Lee, David S. M., Ghanem, Louis R., Barash, Yoseph
Publicado 2020

IL-3 and Oncogenic Abl Regulate the Myeloblast Transcriptome by Altering mRNA Stability

por Ernst, Jason, Ghanem, Louis, Bar-Joseph, Ziv, McNamara, Michael, Brown, Jason, Steinman, Richard A.
Publicado 2009

Disrupting upstream translation in mRNAs is associated with human disease

por Lee, David S. M., Park, Joseph, Kromer, Andrew, Baras, Aris, Rader, Daniel J., Ritchie, Marylyn D., Ghanem, Louis R., Barash, Yoseph
Publicado 2021

The poly(C)-binding protein Pcbp2 is essential for CD4(+) T cell activation and proliferation

por Martinelli, Massimo, Aguilar, Gabrielle, Lee, David S.M., Kromer, Andrew, Nguyen, Nhu, Wilkins, Benjamin J., Akimova, Tatiana, Beier, Ulf H., Ghanem, Louis R.
Publicado 2022

Patient-derived Colonoids From Disease-spared Tissue Retain Inflammatory Bowel Disease-specific Transcriptomic Signatures

por Karakasheva, Tatiana A., Zhou, Yusen, Xie, Hongbo M., Soto, Gloria E., Johnson, Tiana D., Stoltz, Madison A., Roach, Daana M., Nema, Noor, Umeweni, Chizoba N., Naughton, Kaitlyn, Dolinsky, Lauren, Pippin, James A., Wells, Andrew D., Grant, Struan F. A., Ghanem, Louis, Terry, Natalie, Muir, Amanda B., Hamilton, Kathryn E.
Publicado 2023

Variant-to-Gene-Mapping Analyses Reveal a Role for the Hypothalamus in Genetic Susceptibility to Inflammatory Bowel Disease

por Lasconi, Chiara, Pahl, Matthew C., Cousminer, Diana L., Doege, Claudia A., Chesi, Alessandra, Hodge, Kenyaita M., Leonard, Michelle E., Lu, Sumei, Johnson, Matthew E., Su, Chun, Hammond, Reza K., Pippin, James A., Terry, Natalie A., Ghanem, Louis R., Leibel, Rudolph L., Wells, Andrew D., Grant, Struan F.A.
Publicado 2020

Lactate Limits T Cell Proliferation via the NAD(H) Redox State

por Quinn, William J., Jiao, Jing, TeSlaa, Tara, Stadanlick, Jason, Wang, Zhonglin, Wang, Liqing, Akimova, Tatiana, Angelin, Alessia, Schäfer, Patrick M., Cully, Michelle D., Perry, Caroline, Kopinski, Piotr K., Guo, Lili, Blair, Ian A., Ghanem, Louis R., Leibowitz, Michael S., Hancock, Wayne W., Moon, Edmund K., Levine, Matthew H., Eruslanov, Evgeniy B., Wallace, Douglas C., Baur, Joseph A., Beier, Ulf H.
Publicado 2020

3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity

por Trang, Khanh B., Pahl, Matthew C., Pippin, James A., Su, Chun, Littleton, Sheridan H., Sharma, Prabhat, Kulkarni, Nikhil N., Ghanem, Louis R., Terry, Natalie A., O’Brien, Joan M., Wagley, Yadav, Hankenson, Kurt D., Jermusyk, Ashley, Hoskins, Jason W., Amundadottir, Laufey T., Xu, Mai, Brown, Kevin M, Anderson, Stewart A., Yang, Wenli, Titchenell, Paul M., Seale, Patrick, Cook, Laura, Levings, Megan K., Zemel, Babette S., Chesi, Alessandra, Wells, Andrew D., Grant, Struan F.A.
Publicado 2023

CYP11B1 variants influence skeletal maturation via alternative splicing

por Grgic, Olja, Gazzara, Matthew R., Chesi, Alessandra, Medina-Gomez, Carolina, Cousminer, Diana L., Mitchell, Jonathan A., Prijatelj, Vid, de Vries, Jard, Shevroja, Enisa, McCormack, Shana E., Kalkwarf, Heidi J., Lappe, Joan M., Gilsanz, Vicente, Oberfield, Sharon E., Shepherd, John A., Kelly, Andrea, Mahboubi, Soroosh, Faucz, Fabio R., Feelders, Richard A., de Jong, Frank H., Uitterlinden, Andre G., Visser, Jenny A., Ghanem, Louis R., Wolvius, Eppo B., Hofland, Leo J., Stratakis, Constantine A., Zemel, Babette S., Barash, Yoseph, Grant, Struan F. A., Rivadeneira, Fernando
Publicado 2021