Using genome editing to engineer universal platelets

por Lawrence, Moyra, Mueller, Annett, Ghevaert, Cedric
Publicado 2019

Beyond Clotting: A Role of Platelets in CNS Repair?

por Rivera, Francisco J., Kazanis, Ilias, Ghevaert, Cedric, Aigner, Ludwig
Publicado 2016

Brain-derived Neurotrophic Factor in Megakaryocytes

por Chacón-Fernández, Pedro, Säuberli, Katharina, Colzani, Maria, Moreau, Thomas, Ghevaert, Cedric, Barde, Yves-Alain
Publicado 2016

Process analysis of pluripotent stem cell differentiation to megakaryocytes to make platelets applying European GMP

por Lawrence, Moyra, Evans, Amanda, Moreau, Thomas, Bagnati, Marta, Smart, Matthew, Hassan, Enas, Hasan, Jahid, Pianella, Monica, Kerby, Julie, Ghevaert, Cedric
Publicado 2021

Transcription Factor Levels after Forward Programming of Human Pluripotent Stem Cells with GATA1, FLI1, and TAL1 Determine Megakaryocyte versus Erythroid Cell Fate Decision

por Dalby, Amanda, Ballester-Beltrán, Jose, Lincetto, Chiara, Mueller, Annett, Foad, Nicola, Evans, Amanda, Baye, James, Turro, Ernest, Moreau, Thomas, Tijssen, Marloes R., Ghevaert, Cedric
Publicado 2018

Low-affinity FcγR interactions can decide the fate of novel human IgG-sensitised red blood cells and platelets

por Armour, Kathryn L, Smith, Cheryl S, Turner, Craig P, Kirton, Christopher M, Wilkes, Anthony M, Hadley, Andrew G, Ghevaert, Cedric, Williamson, Lorna M, Clark, Michael R
Publicado 2014

The placenta protects the fetal circulation from anxiety-driven elevations in maternal serum levels of brain-derived neurotrophic factor

por Dingsdale, Hayley, Nan, Xinsheng, Garay, Samantha M., Mueller, Annett, Sumption, Lorna A., Chacón-Fernández, Pedro, Martinez-Garay, Isabel, Ghevaert, Cedric, Barde, Yves-Alain, John, Rosalind M.
Publicado 2021

Hematopoietic stem cell transplantation alters susceptibility to pulmonary hypertension in Bmpr2-deficient mice

por Crosby, Alexi, Toshner, Mark R., Southwood, Mark R., Soon, Elaine, Dunmore, Benjamin J., Groves, Emily, Moore, Stephen, Wright, Penny, Ottersbach, Katrin, Bennett, Cavan, Guerrero, Jose, Ghevaert, Cedric, Morrell, Nicholas W.
Publicado 2018

Mapping the biogenesis of forward programmed megakaryocytes from induced pluripotent stem cells

por Lawrence, Moyra, Shahsavari, Arash, Bornelöv, Susanne, Moreau, Thomas, McDonald, Rebecca, Vallance, Thomas M., Kania, Katarzyna, Paramor, Maike, Baye, James, Perrin, Marion, Steindel, Maike, Jimenez-Gomez, Paula, Penfold, Christopher, Mohorianu, Irina, Ghevaert, Cedric
Publicado 2022

Flow cytometry for near-patient testing in premature neonates reveals variation in platelet function: a novel approach to guide platelet transfusion

por Waller, Amie K., Lantos, Lajos, Sammut, Audrienne, Salgin, Burak, McKinney, Harriet, Foster, Holly R., Kriek, Neline, Gibbins, Jonathan M., Stanworth, Simon J., Garner, Stephen F., Venkatesh, Vidheya, Curley, Anna, Belteki, Gusztav, Ghevaert, Cedric
Publicado 2019

Low input capture Hi-C (liCHi-C) identifies promoter-enhancer interactions at high-resolution

por Tomás-Daza, Laureano, Rovirosa, Llorenç, López-Martí, Paula, Nieto-Aliseda, Andrea, Serra, François, Planas-Riverola, Ainoa, Molina, Oscar, McDonald, Rebecca, Ghevaert, Cedric, Cuatrecasas, Esther, Costa, Dolors, Camós, Mireia, Bueno, Clara, Menéndez, Pablo, Valencia, Alfonso, Javierre, Biola M.
Publicado 2023

Interferon-γ signaling in human iPSC–derived neurons recapitulates neurodevelopmental disorder phenotypes

por Warre-Cornish, Katherine, Perfect, Leo, Nagy, Roland, Duarte, Rodrigo R. R., Reid, Matthew J., Raval, Pooja, Mueller, Annett, Evans, Amanda L., Couch, Amalie, Ghevaert, Cédric, McAlonan, Grainne, Loth, Eva, Murphy, Declan, Powell, Timothy R., Vernon, Anthony C., Srivastava, Deepak P., Price, Jack
Publicado 2020

Sphingolipid dysregulation due to lack of functional KDSR impairs proplatelet formation causing thrombocytopenia

por Bariana, Tadbir K., Labarque, Veerle, Heremans, Jessica, Thys, Chantal, De Reys, Mara, Greene, Daniel, Jenkins, Benjamin, Grassi, Luigi, Seyres, Denis, Burden, Frances, Whitehorn, Deborah, Shamardina, Olga, Papadia, Sofia, Gomez, Keith, BioResource, NIHR, Van Geet, Chris, Koulman, Albert, Ouwehand, Willem H., Ghevaert, Cedric, Frontini, Mattia, Turro, Ernest, Freson, Kathleen
Publicado 2019

Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging

por Ho, Ya-Hsuan, del Toro, Raquel, Rivera-Torres, José, Rak, Justyna, Korn, Claudia, García-García, Andrés, Macías, David, González-Gómez, Cristina, del Monte, Alberto, Wittner, Monika, Waller, Amie K., Foster, Holly R., López-Otín, Carlos, Johnson, Randall S., Nerlov, Claus, Ghevaert, Cedric, Vainchenker, William, Louache, Fawzia, Andrés, Vicente, Méndez-Ferrer, Simón
Publicado 2019

Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner

por Luis, Tiago C., Barkas, Nikolaos, Carrelha, Joana, Giustacchini, Alice, Mazzi, Stefania, Norfo, Ruggiero, Wu, Bishan, Aliouat, Affaf, Guerrero, Jose A., Rodriguez-Meira, Alba, Bouriez-Jones, Tiphaine, Macaulay, Iain C., Jasztal, Maria, Zhu, Guangheng, Ni, Heyu, Robson, Matthew J., Blakely, Randy D., Mead, Adam J., Nerlov, Claus, Ghevaert, Cedric, Jacobsen, Sten Eirik W.
Publicado 2023

Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming

por Moreau, Thomas, Evans, Amanda L., Vasquez, Louella, Tijssen, Marloes R., Yan, Ying, Trotter, Matthew W., Howard, Daniel, Colzani, Maria, Arumugam, Meera, Wu, Wing Han, Dalby, Amanda, Lampela, Riina, Bouet, Guenaelle, Hobbs, Catherine M., Pask, Dean C., Payne, Holly, Ponomaryov, Tatyana, Brill, Alexander, Soranzo, Nicole, Ouwehand, Willem H., Pedersen, Roger A., Ghevaert, Cedric
Publicado 2016

Corrigendum: Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming

por Moreau, Thomas, Evans, Amanda L., Vasquez, Louella, Tijssen, Marloes R., Yan, Ying, Trotter, Matthew W., Howard, Daniel, Colzani, Maria, Arumugam, Meera, Wu, Wing Han, Dalby, Amanda, Lampela, Riina, Bouet, Guenaelle, Hobbs, Catherine M., Pask, Dean C., Payne, Holly, Ponomaryov, Tatyana, Brill, Alexander, Soranzo, Nicole, Ouwehand, Willem H., Pedersen, Roger A., Ghevaert, Cedric
Publicado 2017

Highly efficient platelet generation in lung vasculature reproduced by microfluidics

por Zhao, Xiaojuan, Alibhai, Dominic, Walsh, Tony G., Tarassova, Nathalie, Englert, Maximilian, Birol, Semra Z., Li, Yong, Williams, Christopher M., Neal, Chris R., Burkard, Philipp, Cross, Stephen J., Aitken, Elizabeth W., Waller, Amie K., Beltrán, José Ballester, Gunning, Peter W., Hardeman, Edna C., Agbani, Ejaife O., Nieswandt, Bernhard, Hers, Ingeborg, Ghevaert, Cedric, Poole, Alastair W.
Publicado 2023

STAT1 is essential for HSC function and maintains MHCII(hi) stem cells that resist myeloablation and neoplastic expansion

por Li, Juan, Williams, Matthew J., Park, Hyun Jung, Bastos, Hugo P., Wang, Xiaonan, Prins, Daniel, Wilson, Nicola K., Johnson, Carys, Sham, Kendig, Wantoch, Michelle, Watcham, Sam, Kinston, Sarah J., Pask, Dean C., Hamilton, Tina L., Sneade, Rachel, Waller, Amie K., Ghevaert, Cedric, Vassiliou, George S., Laurenti, Elisa, Kent, David G., Göttgens, Berthold, Green, Anthony R.
Publicado 2022

CRLF3 plays a key role in the final stage of platelet genesis and is a potential therapeutic target for thrombocythaemia

por Bennett, Cavan, Lawrence, Moyra, Guerrero, Jose A., Stritt, Simon, Waller, Amie K., Yan, Yahui, Mifsud, Richard W., Ballester-Beltran, Jose, Baig, Ayesha, Mueller, Annett, Mayer, Louisa, Warland, James, Penkett, Christopher J., Akbari, Parsa, Moreau, Thomas, Evans, Amanda L., Mookerjee, Souradip, Hoffman, Gary J., Saeb-Parsy, Kourosh, Adams, David J., Couzens, Amber L., Bender, Markus, Erber, Wendy N., Nieswandt, Bernhard, Read, Randy J., Ghevaert, Cedric
Publicado 2022