Structural Context of Disease-Associated Mutations and Putative Mechanism of Autoinhibition Revealed by X-Ray Crystallographic Analysis of the EZH2-SET Domain

por Antonysamy, Stephen, Condon, Bradley, Druzina, Zhanna, Bonanno, Jeffrey B., Gheyi, Tarun, Zhang, Feiyu, MacEwan, Iain, Zhang, Aiping, Ashok, Sheela, Rodgers, Logan, Russell, Marijane, Gately Luz, John
Publicado 2013

LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2

por Nguyen, Hannah, Allali-Hassani, Abdellah, Antonysamy, Stephen, Chang, Shawn, Chen, Lisa Hong, Curtis, Carmen, Emtage, Spencer, Fan, Li, Gheyi, Tarun, Li, Fengling, Liu, Shichong, Martin, Joseph R., Mendel, David, Olsen, Jonathan B., Pelletier, Laura, Shatseva, Tatiana, Wu, Song, Zhang, Feiyu Fred, Arrowsmith, Cheryl H., Brown, Peter J., Campbell, Robert M., Garcia, Benjamin A., Barsyte-Lovejoy, Dalia, Mader, Mary, Vedadi, Masoud
Publicado 2015

Structural basis for GPR40 allosteric agonism and incretin stimulation

por Ho, Joseph D., Chau, Betty, Rodgers, Logan, Lu, Frances, Wilbur, Kelly L., Otto, Keith A., Chen, Yanyun, Song, Min, Riley, Jonathan P., Yang, Hsiu-Chiung, Reynolds, Nichole A., Kahl, Steven D., Lewis, Anjana Patel, Groshong, Christopher, Madsen, Russell E., Conners, Kris, Lineswala, Jayana P., Gheyi, Tarun, Saflor, Melbert-Brian Decipulo, Lee, Matthew R., Benach, Jordi, Baker, Kenton A., Montrose-Rafizadeh, Chahrzad, Genin, Michael J., Miller, Anne R., Hamdouchi, Chafiq
Publicado 2018