Melanocortin 1 receptor regulates cholesterol and bile acid metabolism in the liver

por Thapa, Keshav, Kadiri, James J, Saukkonen, Karla, Pennanen, Iida, Ghimire, Bishwa, Cai, Minying, Savontaus, Eriika, Rinne, Petteri
Publicado 2023

STAT3 activation in large granular lymphocyte leukemia is associated with cytokine signaling and DNA hypermethylation

por Kim, Daehong, Park, Giljun, Huuhtanen, Jani, Ghimire, Bishwa, Rajala, Hanna, Moriggl, Richard, Chan, Wing C., Kankainen, Matti, Myllymäki, Mikko, Mustjoki, Satu
Publicado 2021

Analysis of human brain tissue derived from DBS surgery

por Kangas, Salla M., Teppo, Jaakko, Lahtinen, Maija J., Suoranta, Anu, Ghimire, Bishwa, Mattila, Pirkko, Uusimaa, Johanna, Varjosalo, Markku, Katisko, Jani, Hinttala, Reetta
Publicado 2022

RUNX1 mutations in blast-phase chronic myeloid leukemia associate with distinct phenotypes, transcriptional profiles, and drug responses

por Adnan Awad, Shady, Dufva, Olli, Ianevski, Aleksandr, Ghimire, Bishwa, Koski, Jan, Maliniemi, Pilvi, Thomson, Daniel, Schreiber, Andreas, Heckman, Caroline A., Koskenvesa, Perttu, Korhonen, Matti, Porkka, Kimmo, Branford, Susan, Aittokallio, Tero, Kankainen, Matti, Mustjoki, Satu
Publicado 2020

Epigenetic Silencing of the Key Antioxidant Enzyme Catalase in Karyotypically Abnormal Human Pluripotent Stem Cells

por Konki, Mikko, Pasumarthy, Kalyan, Malonzo, Maia, Sainio, Annele, Valensisi, Cristina, Söderström, Mirva, Emani, Maheswara Reddy, Stubb, Aki, Närvä, Elisa, Ghimire, Bishwa, Laiho, Asta, Järveläinen, Hannu, Lahesmaa, Riitta, Lähdesmäki, Harri, Hawkins, R. David, Lund, Riikka J.
Publicado 2016

Patient-tailored design for selective co-inhibition of leukemic cell subpopulations

por Ianevski, Aleksandr, Lahtela, Jenni, Javarappa, Komal K., Sergeev, Philipp, Ghimire, Bishwa R., Gautam, Prson, Vähä-Koskela, Markus, Turunen, Laura, Linnavirta, Nora, Kuusanmäki, Heikki, Kontro, Mika, Porkka, Kimmo, Heckman, Caroline A., Mattila, Pirkko, Wennerberg, Krister, Giri, Anil K., Aittokallio, Tero
Publicado 2021

Peripheral blood DNA methylation differences in twin pairs discordant for Alzheimer’s disease

por Konki, Mikko, Malonzo, Maia, Karlsson, Ida K., Lindgren, Noora, Ghimire, Bishwa, Smolander, Johannes, Scheinin, Noora M., Ollikainen, Miina, Laiho, Asta, Elo, Laura L., Lönnberg, Tapio, Röyttä, Matias, Pedersen, Nancy L., Kaprio, Jaakko, Lähdesmäki, Harri, Rinne, Juha O., Lund, Riikka J.
Publicado 2019

A novel variant in SMG9 causes intellectual disability, confirming a role for nonsense-mediated decay components in neurocognitive development

por Rahikkala, Elisa, Urpa, Lea, Ghimire, Bishwa, Topa, Hande, Kurki, Mitja I., Koskela, Maryna, Airavaara, Mikko, Hämäläinen, Eija, Pylkäs, Katri, Körkkö, Jarmo, Savolainen, Helena, Suoranta, Anu, Bertoli-Avella, Aida, Rolfs, Arndt, Mattila, Pirkko, Daly, Mark, Palotie, Aarno, Pietiläinen, Olli, Moilanen, Jukka, Kuismin, Outi
Publicado 2022

Umbilical cord blood DNA methylation in children who later develop type 1 diabetes

por Laajala, Essi, Kalim, Ubaid Ullah, Grönroos, Toni, Rasool, Omid, Halla-aho, Viivi, Konki, Mikko, Kattelus, Roosa, Mykkänen, Juha, Nurmio, Mirja, Vähä-Mäkilä, Mari, Kallionpää, Henna, Lietzén, Niina, Ghimire, Bishwa R., Laiho, Asta, Hyöty, Heikki, Elo, Laura L., Ilonen, Jorma, Knip, Mikael, Lund, Riikka J., Orešič, Matej, Veijola, Riitta, Lähdesmäki, Harri, Toppari, Jorma, Lahesmaa, Riitta
Publicado 2022