Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

por Giambartolomei, Claudia, Vukcevic, Damjan, Schadt, Eric E., Franke, Lude, Hingorani, Aroon D., Wallace, Chris, Plagnol, Vincent
Publicado 2014

Leveraging eQTLs to identify individual-level tissue of interest for a complex trait

por Majumdar, Arunabha, Giambartolomei, Claudia, Cai, Na, Haldar, Tanushree, Schwarz, Tommer, Gandal, Michael, Flint, Jonathan, Pasaniuc, Bogdan
Publicado 2021

Effects of Genetically Determined Iron Status on Risk of Venous Thromboembolism and Carotid Atherosclerotic Disease: A Mendelian Randomization Study

por Gill, Dipender, Brewer, Christopher F., Monori, Grace, Trégouët, David‐Alexandre, Franceschini, Nora, Giambartolomei, Claudia, Tzoulaki, Ioanna, Dehghan, Abbas
Publicado 2019

Early and current socio-economic position and cardiometabolic risk factors in the Indian Migration Study

por Sovio, Ulla, Giambartolomei, Claudia, Kinra, Sanjay, Bowen, Liza, Dudbridge, Frank, Nitsch, Dorothea, Smith, George Davey, Ebrahim, Shah, Ben-Shlomo, Yoav
Publicado 2013

Post-GWAS methodologies for localisation of functional non-coding variants: ANGPTL3

por Oldoni, Federico, Palmen, Jutta, Giambartolomei, Claudia, Howard, Philip, Drenos, Fotios, Plagnol, Vincent, Humphries, Steve E., Talmud, Philippa J., Smith, Andrew J.P.
Publicado 2016

Genetic complexity in hypertrophic cardiomyopathy revealed by high-throughput sequencing

por Lopes, Luis R, Zekavati, Anna, Syrris, Petros, Hubank, Mike, Giambartolomei, Claudia, Dalageorgou, Chrysoula, Jenkins, Sharon, McKenna, William, Plagnol, Vincent, Elliott, Perry M
Publicado 2013

Genetic variants alter T-bet binding and gene expression in mucosal inflammatory disease

por Soderquest, Katrina, Hertweck, Arnulf, Giambartolomei, Claudia, Henderson, Stephen, Mohamed, Rami, Goldberg, Rimma, Perucha, Esperanza, Franke, Lude, Herrero, Javier, Plagnol, Vincent, Jenner, Richard G., Lord, Graham M.
Publicado 2017

Machine learning methods applied to genotyping data capture interactions between single nucleotide variants in late onset Alzheimer's disease

por Arnal Segura, Magdalena, Bini, Giorgio, Fernandez Orth, Dietmar, Samaras, Eleftherios, Kassis, Maya, Aisopos, Fotis, Rambla De Argila, Jordi, Paliouras, George, Garrard, Peter, Giambartolomei, Claudia, Tartaglia, Gian Gaetano
Publicado 2022

Optimized high-throughput screening of non-coding variants identified from genome-wide association studies

por Morova, Tunc, Ding, Yi, Huang, Chia-Chi F, Sar, Funda, Schwarz, Tommer, Giambartolomei, Claudia, Baca, Sylvan C, Grishin, Dennis, Hach, Faraz, Gusev, Alexander, Freedman, Matthew L, Pasaniuc, Bogdan, Lack, Nathan A
Publicado 2022

Use of Allele-Specific FAIRE to Determine Functional Regulatory Polymorphism Using Large-Scale Genotyping Arrays

por Smith, Andrew J. P., Howard, Philip, Shah, Sonia, Eriksson, Per, Stender, Stefan, Giambartolomei, Claudia, Folkersen, Lasse, Tybjærg-Hansen, Anne, Kumari, Meena, Palmen, Jutta, Hingorani, Aroon D., Talmud, Philippa J., Humphries, Steve E.
Publicado 2012

HAPRAP: a haplotype-based iterative method for statistical fine mapping using GWAS summary statistics

por Zheng, Jie, Rodriguez, Santiago, Laurin, Charles, Baird, Denis, Trela-Larsen, Lea, Erzurumluoglu, Mesut A, Zheng, Yi, White, Jon, Giambartolomei, Claudia, Zabaneh, Delilah, Morris, Richard, Kumari, Meena, Casas, Juan P, Hingorani, Aroon D, Evans, David M, Gaunt, Tom R, Day, Ian N M
Publicado 2017

Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes

por Schmidt, Amand F., Joshi, Roshni, Gordillo-Marañón, Maria, Drenos, Fotios, Charoen, Pimphen, Giambartolomei, Claudia, Bis, Joshua C., Gaunt, Tom R., Hughes, Alun D., Lawlor, Deborah A., Wong, Andrew, Price, Jackie F., Chaturvedi, Nishi, Wannamethee, Goya, Franceschini, Nora, Kivimaki, Mika, Hingorani, Aroon D., Finan, Chris
Publicado 2023

Relationships between computer-extracted mammographic texture pattern features and BRCA1/2mutation status: a cross-sectional study

por Gierach, Gretchen L, Li, Hui, Loud, Jennifer T, Greene, Mark H, Chow, Catherine K, Lan, Li, Prindiville, Sheila A, Eng-Wong, Jennifer, Soballe, Peter W, Giambartolomei, Claudia, Mai, Phuong L, Galbo, Claudia E, Nichols, Kathryn, Calzone, Kathleen A, Olopade, Olufunmilayo I, Gail, Mitchell H, Giger, Maryellen L
Publicado 2014

Differential Activity of Transcribed Enhancers in the Prefrontal Cortex of 537 cases with Schizophrenia and Controls

por Hauberg, Mads E., Fullard, John F., Zhu, Lingxue, Cohain, Ariella, Giambartolomei, Claudia, Misir, Ruth, Reach, Sarah, Johnson, Jessica S., Wang, Minghui, Mattheisen, Manuel, Børglum, Anders Dupont, Zhang, Bin, Sieberts, Solveig K., Peters, Mette A., Domenici, Enrico, Schadt, Eric E., Devlin, Bernie, Sklar, Pamela, Roeder, Kathryn, Roussos, Panos
Publicado 2018

Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS

por Dobbyn, Amanda, Huckins, Laura M., Boocock, James, Sloofman, Laura G., Glicksberg, Benjamin S., Giambartolomei, Claudia, Hoffman, Gabriel E., Perumal, Thanneer M., Girdhar, Kiran, Jiang, Yan, Raj, Towfique, Ruderfer, Douglas M., Kramer, Robin S., Pinto, Dalila, Akbarian, Schahram, Roussos, Panos, Domenici, Enrico, Devlin, Bernie, Sklar, Pamela, Stahl, Eli A., Sieberts, Solveig K.
Publicado 2018

Identifying low density lipoprotein cholesterol associated variants in the Annexin A2 (ANXA2) gene

por Fairoozy, Roaa Hani, Cooper, Jackie, White, Jon, Giambartolomei, Claudia, Folkersen, Lasse, Wannamethee, S. Goya, Jefferis, Barbara J., Whincup, Peter, Ben-Shlomo, Yoav, Kumari, Meena, Kivimaki, Mika, Wong, Andrew, Hardy, Rebecca, Kuh, Diana, Gaunt, Tom R., Casas, J.P., McLachlan, Stela, Price, Jackie F., Hingorani, Aroon, Franco-Cereceda, Anders, Grewal, Thomas, Kalea, Anastasia Z., Humphries, Steve E.
Publicado 2017

Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease

por Schmidt, Amand F., Hunt, Nicholas B., Gordillo-Marañón, Maria, Charoen, Pimphen, Drenos, Fotios, Kivimaki, Mika, Lawlor, Deborah A., Giambartolomei, Claudia, Papacosta, Olia, Chaturvedi, Nishi, Bis, Joshua C., O’Donnell, Christopher J., Wannamethee, Goya, Wong, Andrew, Price, Jackie F., Hughes, Alun D., Gaunt, Tom R., Franceschini, Nora, Mook-Kanamori, Dennis O., Zwierzyna, Magdalena, Sofat, Reecha, Hingorani, Aroon D., Finan, Chris
Publicado 2021

Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential

por Kneppers, Jeroen, Severson, Tesa M., Siefert, Joseph C., Schol, Pieter, Joosten, Stacey E. P., Yu, Ivan Pak Lok, Huang, Chia-Chi Flora, Morova, Tunç, Altıntaş, Umut Berkay, Giambartolomei, Claudia, Seo, Ji-Heui, Baca, Sylvan C., Carneiro, Isa, Emberly, Eldon, Pasaniuc, Bogdan, Jerónimo, Carmen, Henrique, Rui, Freedman, Matthew L., Wessels, Lodewyk F. A., Lack, Nathan A., Bergman, Andries M., Zwart, Wilbert
Publicado 2022

Replication and Characterization of Association between ABO SNPs and Red Blood Cell Traits by Meta-Analysis in Europeans

por McLachlan, Stela, Giambartolomei, Claudia, White, Jon, Charoen, Pimphen, Wong, Andrew, Finan, Chris, Engmann, Jorgen, Shah, Tina, Hersch, Micha, Podmore, Clara, Cavadino, Alana, Jefferis, Barbara J., Dale, Caroline E., Hypponen, Elina, Morris, Richard W., Casas, Juan P., Kumari, Meena, Ben-Shlomo, Yoav, Gaunt, Tom R., Drenos, Fotios, Langenberg, Claudia, Kuh, Diana, Kivimaki, Mika, Rueedi, Rico, Waeber, Gerard, Hingorani, Aroon D., Price, Jacqueline F., Walker, Ann P.
Publicado 2016

Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure

por Rasooly, Danielle, Peloso, Gina M., Pereira, Alexandre C., Dashti, Hesam, Giambartolomei, Claudia, Wheeler, Eleanor, Aung, Nay, Ferolito, Brian R., Pietzner, Maik, Farber-Eger, Eric H., Wells, Quinn Stanton, Kosik, Nicole M., Gaziano, Liam, Posner, Daniel C., Bento, A. Patrícia, Hui, Qin, Liu, Chang, Aragam, Krishna, Wang, Zeyuan, Charest, Brian, Huffman, Jennifer E., Wilson, Peter W. F., Phillips, Lawrence S., Whittaker, John, Munroe, Patricia B., Petersen, Steffen E., Cho, Kelly, Leach, Andrew R., Magariños, María Paula, Gaziano, John Michael, Langenberg, Claudia, Sun, Yan V., Joseph, Jacob, Casas, Juan P.
Publicado 2023