Aptamer-siRNA Chimeras: Discovery, Progress, and Future Prospects

por Kruspe, Sven, Giangrande, Paloma H.
Publicado 2017

On integrity

por Bricker-Anthony, Courtney, Giangrande, Paloma H.
Publicado 2022

Smooth muscle cell-targeted RNA ligand promotes accelerated reendothelialization in a swine peripheral injury model

por Lei, Beilei, Liu, Linda B., Stokes, Lauren, Giangrande, Paloma H., Miller, Francis J., Yazdani, Saami K.
Publicado 2023

Aptamers as Diagnostic Tools in Cancer

por Ruiz Ciancio, Dario, Vargas, Mauricio R., Thiel, William H., Bruno, Martin A., Giangrande, Paloma H., Mestre, María Belén
Publicado 2018

Local intraluminal delivery of a smooth muscle-targeted RNA ligand inhibits neointima growth in a porcine model of peripheral vascular disease

por Yazdani, Saami K., Lei, Beilei, Cawthon, Claire V., Cooper, Kathryn, Huett, Clifton, Giangrande, Paloma H., Miller, Francis J.
Publicado 2022

Methods for Evaluating Cell-Specific, Cell-Internalizing RNA Aptamers

por Hernandez, Luiza I., Flenker, Katie S., Hernandez, Frank J., Klingelhutz, Aloysius J., II, James O. McNamara, Giangrande, Paloma H.
Publicado 2013

Aptamers in Bordeaux, 24–25 June 2016

por Toulmé, Jean-Jacques, Giangrande, Paloma H., Mayer, Günter, Suess, Beatrix, Ducongé, Frédéric, Sullenger, Bruce, de Franciscis, Vittorio, Darfeuille, Fabien, Peyrin, Eric
Publicado 2017

Delivery of Cell-Specific Aptamers to the Arterial Wall with an Occlusion Perfusion Catheter

por Udofot, Ofonime, Lin, Li-Hsien, Thiel, William H., Erwin, Megan, Turner, Emily, Miller, Francis J., Giangrande, Paloma H., Yazdani, Saami K.
Publicado 2019

Rapid Identification of Cell-Specific, Internalizing RNA Aptamers with Bioinformatics Analyses of a Cell-Based Aptamer Selection

por Thiel, William H., Bair, Thomas, Peek, Andrew S., Liu, Xiuying, Dassie, Justin, Stockdale, Katie R., Behlke, Mark A., Miller, Francis J., Giangrande, Paloma H.
Publicado 2012

Inhalation of an RNA aptamer that selectively binds extracellular histones protects from acute lung injury

por Lei, Beilei, Wang, Chaojian, Snow, Kamie, Graton, Murilo E., Tighe, Robert M., Fager, Ammon M., Hoffman, Maureane R., Giangrande, Paloma H., Miller, Francis J.
Publicado 2023

Aptamer-miRNA-212 Conjugate Sensitizes NSCLC Cells to TRAIL

por Iaboni, Margherita, Russo, Valentina, Fontanella, Raffaela, Roscigno, Giuseppina, Fiore, Danilo, Donnarumma, Elvira, Esposito, Carla Lucia, Quintavalle, Cristina, Giangrande, Paloma H, de Franciscis, Vittorio, Condorelli, Gerolama
Publicado 2016

Selection of a novel cell-internalizing RNA aptamer specific for CD22 antigen in B cell acute lymphoblastic leukemia

por Ruiz-Ciancio, Dario, Lin, Li-Hsien, Veeramani, Suresh, Barros, Maya N., Sanchez, Diego, Di Bartolo, Ary Lautaro, Masone, Diego, Giangrande, Paloma H., Mestre, María Belén, Thiel, William H.
Publicado 2023

Delivery of chemo-sensitizing siRNAs to HER2(+)-breast cancer cells using RNA aptamers

por Thiel, Kristina W., Hernandez, Luiza I., Dassie, Justin P., Thiel, William H., Liu, Xiuying, Stockdale, Katie R., Rothman, Alissa M., Hernandez, Frank J., McNamara, James O., Giangrande, Paloma H.
Publicado 2012

Amnio acid substitution at position 298 of human glucose-6 phosphatase-α significantly impacts its stability in mammalian cells

por Cao, Jingsong, Markel, Arianna, Hanahoe, Erin, Ketova, Tatiana, Mihai, Cosmin, Zalinger, Zach, Marquardt, David, Amato, Nicholas J., Cheng, Yi Min, Reid, David W., Dousis, Athanasios, Giangrande, Paloma H., Schultz, Joshua R., Martini, Paolo G. V., Finn, Patrick F.
Publicado 2023

Targeted Inhibition of Prostate Cancer Metastases with an RNA Aptamer to Prostate-specific Membrane Antigen

por Dassie, Justin P, Hernandez, Luiza I, Thomas, Gregory S, Long, Matthew E, Rockey, William M, Howell, Craig A, Chen, Yani, Hernandez, Frank J, Liu, Xiu Ying, Wilson, Mary E, Allen, Lee-Ann, Vaena, Daniel A, Meyerholz, David K, Giangrande, Paloma H
Publicado 2014

Combination of protein and cell internalization SELEX identifies a potential RNA therapeutic and delivery platform to treat EphA2-expressing tumors

por Santana-Viera, Laura, Dassie, Justin P., Rosàs-Lapeña, Marta, Garcia-Monclús, Silvia, Chicón-Bosch, Mariona, Pérez-Capó, Marina, Pozo, Lidia del, Sanchez-Serra, Sara, Almacellas-Rabaiget, Olga, Maqueda-Marcos, Susana, López-Alemany, Roser, Thiel, William H., Giangrande, Paloma H., Tirado, Oscar M.
Publicado 2023

RNA inhibitors of nuclear proteins responsible for multiple organ dysfunction syndrome

por Urak, Kevin T., Blanco, Giselle N., Shubham, Shambhavi, Lin, Li-Hsien, Dassie, Justin P., Thiel, William H., Chen, Yani, Sonkar, Vijay Kumar, Lei, Beilei, Murthy, Shubha, Gutierrez, Wade R., Wilson, Mary E., Stiber, Jonathan A., Klesney-Tait, Julia, Dayal, Sanjana, Miller, Francis J., Giangrande, Paloma H.
Publicado 2019

Synthetic human ABCB4 mRNA therapy rescues severe liver disease phenotype in a BALB/c.Abcb4(−/−) mouse model of PFIC3

por Wei, Guangyan, Cao, Jingsong, Huang, Pinzhu, An, Ping, Badlani, Disha, Vaid, Kahini A., Zhao, Shuangshuang, Wang, David Q-H., Zhuo, Jenny, Yin, Ling, Frassetto, Andrea, Markel, Arianna, Presnyak, Vladimir, Gandham, Srujan, Hua, Serenus, Lukacs, Christine, Finn, Patrick F., Giangrande, Paloma H., Martini, Paolo G.V., Popov, Yury V.
Publicado 2020

Rapid and Sensitive Detection of Breast Cancer Cells in Patient Blood with Nuclease-Activated Probe Technology

por Kruspe, Sven, Dickey, David D., Urak, Kevin T., Blanco, Giselle N., Miller, Matthew J., Clark, Karen C., Burghardt, Elliot, Gutierrez, Wade R., Phadke, Sneha D., Kamboj, Sukriti, Ginader, Timothy, Smith, Brian J., Grimm, Sarah K., Schappet, James, Ozer, Howard, Thomas, Alexandra, McNamara, James O., Chan, Carlos H., Giangrande, Paloma H.
Publicado 2017

Impact of stereopure chimeric backbone chemistries on the potency and durability of gene silencing by RNA interference

por Liu, Wei, Iwamoto, Naoki, Marappan, Subramanian, Luu, Khoa, Tripathi, Snehlata, Purcell-Estabrook, Erin, Shelke, Juili Dilip, Shah, Himali, Lamattina, Anthony, Pan, Qianli, Schrand, Brett, Favaloro, Frank, Bedekar, Mugdha, Chatterjee, Arindom, Desai, Jigar, Kawamoto, Tomomi, Lu, Genliang, Metterville, Jake, Samaraweera, Milinda, Prakasha, Priyanka Shiva, Yang, Hailin, Yin, Yuan, Yu, Hui, Giangrande, Paloma H, Byrne, Michael, Kandasamy, Pachamuthu, Vargeese, Chandra
Publicado 2023