Antileukotriene therapy by reducing tau phosphorylation improves synaptic integrity and cognition of P301S transgenic mice

por Giannopoulos, Phillip F., Chiu, Jian, Praticò, Domenico
Publicado 2018

Brain 5‐lipoxygenase over‐expression worsens memory, synaptic integrity, and tau pathology in the P301S mice

por Vagnozzi, Alana N., Giannopoulos, Phillip F., Praticò, Domenico
Publicado 2017

The direct role of 5-lipoxygenase on tau pathology, synaptic integrity and cognition in a mouse model of tauopathy

por Vagnozzi, Alana N., Giannopoulos, Phillip F., Praticò, Domenico
Publicado 2017

Adeno-associated virus-mediated brain delivery of 5-lipoxygenase modulates the AD-like phenotype of APP mice

por Chu, Jin, Giannopoulos, Phillip F, Ceballos-Diaz, Carolina, Golde, Todd E, Pratico, Domenico
Publicado 2012

Gene Knockout of 5-Lipoxygenase Rescues Synaptic Dysfunction and Improves Memory in the Triple-Transgenic Model of Alzheimer’s Disease

por Giannopoulos, Phillip F., Chu, Jin, Joshi, Yash B., Sperow, Margaret, Li, Jin-Luo, Kirby, Lynn G., Praticò, Domenico
Publicado 2013