Identification of small molecules and related targets that modulate tau pathology in a seeded primary neuron model

por Gibbons, Garrett S., Gould, Hailey, Lee, Virginia M.-Y., Crowe, Alex, Brunden, Kurt R.
Publicado 2023

Astroglial tau pathology alone preferentially concentrates at sulcal depths in chronic traumatic encephalopathy neuropathologic change

por Arena, John D, Johnson, Victoria E, Lee, Edward B, Gibbons, Garrett S, Smith, Douglas H, Trojanowski, John Q, Stewart, William
Publicado 2020

Detection of Alzheimer’s disease (AD) specific tau pathology with conformation-selective anti-tau monoclonal antibody in co-morbid frontotemporal lobar degeneration-tau (FTLD-tau)...

por Gibbons, Garrett S., Kim, Soo-Jung, Robinson, John L., Changolkar, Lakshmi, Irwin, David J., Shaw, Leslie M., Lee, Virginia M.-Y., Trojanowski, John Q.
Publicado 2019

Tau immunotherapy is associated with glial responses in FTLD-tau

por Kim, Boram, Mikytuck, Bailey, Suh, Eunran, Gibbons, Garrett S., Van Deerlin, Vivianna M., Vaishnavi, Sanjeev N., Spindler, Meredith A., Massimo, Lauren, Grossman, Murray, Trojanowski, John Q., Irwin, David J., Lee, Edward B.
Publicado 2021

Transmission of tauopathy strains is independent of their isoform composition

por He, Zhuohao, McBride, Jennifer D., Xu, Hong, Changolkar, Lakshmi, Kim, Soo-jung, Zhang, Bin, Narasimhan, Sneha, Gibbons, Garrett S., Guo, Jing L., Kozak, Michael, Schellenberg, Gerard D., Trojanowski, John Q., Lee, Virginia M. -Y.
Publicado 2020

Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer’s disease

por Gibbons, Garrett S., Kim, Soo-Jung, Wu, Qihui, Riddle, Dawn M., Leight, Susan N., Changolkar, Lakshmi, Xu, Hong, Meymand, Emily S., O’Reilly, Mia, Zhang, Bin, Brunden, Kurt R., Trojanowski, John Q., Lee, Virginia M. Y.
Publicado 2020

In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics

por Xu, Hong, O’Reilly, Mia, Gibbons, Garrett S., Changolkar, Lakshmi, McBride, Jennifer D., Riddle, Dawn M., Zhang, Bin, Stieber, Anna, Nirschl, Jeffrey, Kim, Soo-Jung, Hoxha, Kevt-her, Brunden, Kurt R., Schellenberg, Gerard D., Trojanowski, John Q., Lee, Virginia M.-Y.
Publicado 2021