Maintaining memory of silencing at imprinted differentially methylated regions

por Voon, Hsiao P. J., Gibbons, Richard J.
Publicado 2016

ATRX Contributes to MeCP2-Mediated Pericentric Heterochromatin Organization during Neural Differentiation

por Marano, Domenico, Fioriniello, Salvatore, Fiorillo, Francesca, Gibbons, Richard J., D’Esposito, Maurizio, Della Ragione, Floriana
Publicado 2019

Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX

por Clynes, David, Jelinska, Clare, Xella, Barbara, Ayyub, Helena, Scott, Caroline, Mitson, Matthew, Taylor, Stephen, Higgs, Douglas R., Gibbons, Richard J.
Publicado 2015

ATRX Dysfunction Induces Replication Defects in Primary Mouse Cells

por Clynes, David, Jelinska, Clare, Xella, Barbara, Ayyub, Helena, Taylor, Stephen, Mitson, Matthew, Bachrati, Csanád Z., Higgs, Douglas R., Gibbons, Richard J.
Publicado 2014

Loss of Atrx Affects Trophoblast Development and the Pattern of X-Inactivation in Extraembryonic Tissues

por Garrick, David, Sharpe, Jackie A, Arkell, Ruth, Dobbie, Lorraine, Smith, Andrew J. H, Wood, William G, Higgs, Douglas R, Gibbons, Richard J
Publicado 2006

ATRX Plays a Key Role in Maintaining Silencing at Interstitial Heterochromatic Loci and Imprinted Genes

por Voon, Hsiao P.J., Hughes, Jim R., Rode, Christina, De La Rosa-Velázquez, Inti A., Jenuwein, Thomas, Feil, Robert, Higgs, Douglas R., Gibbons, Richard J.
Publicado 2015

The macroH2A1.2 histone variant links ATRX loss to alternative telomere lengthening.

por Kim, Jeongkyu, Sun, Chongkui, Tran, Andy D., Chin, Pei-Ju, Ruiz, Penelope D., Wang, Kun, Gibbons, Richard J., Gamble, Mathew J., Liu, Yie, Oberdoerffer, Philipp
Publicado 2019

Induction of the alternative lengthening of telomeres pathway by trapping of proteins on DNA

por Rose, Anna M, Goncalves, Tomas, Cunniffe, Siobhan, Geiller, Helene E B, Kent, Thomas, Shepherd, Sam, Ratnaweera, Malitha, O’Sullivan, Roderick J, Gibbons, Richard J, Clynes, David
Publicado 2023

The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription

por Schwab, Rebekka A., Nieminuszczy, Jadwiga, Shah, Fenil, Langton, Jamie, Lopez Martinez, David, Liang, Chih-Chao, Cohn, Martin A., Gibbons, Richard J., Deans, Andrew J., Niedzwiedz, Wojciech
Publicado 2015

A gain-of-function single nucleotide variant creates a new promoter which acts as an orientation-dependent enhancer-blocker

por Bozhilov, Yavor K., Downes, Damien J., Telenius, Jelena, Marieke Oudelaar, A., Olivier, Emmanuel N., Mountford, Joanne C., Hughes, Jim R., Gibbons, Richard J., Higgs, Douglas R.
Publicado 2021

Robust CRISPR/Cas9 Genome Editing of the HUDEP-2 Erythroid Precursor Line Using Plasmids and Single-Stranded Oligonucleotide Donors

por Moir-Meyer, Gemma, Cheong, Pak Leng, Olijnik, Aude-Anais, Brown, Jill, Knight, Samantha, King, Andrew, Kurita, Ryo, Nakamura, Yukio, Gibbons, Richard J., Higgs, Douglas R., Buckle, Veronica J., Babbs, Christian
Publicado 2018

The chromatin remodeller ATRX facilitates diverse nuclear processes, in a stochastic manner, in both heterochromatin and euchromatin

por Truch, Julia, Downes, Damien J., Scott, Caroline, Gür, E. Ravza, Telenius, Jelena M., Repapi, Emmanouela, Schwessinger, Ron, Gosden, Matthew, Brown, Jill M., Taylor, Stephen, Cheong, Pak Leng, Hughes, Jim R., Higgs, Douglas R., Gibbons, Richard J.
Publicado 2022

Generation of bivalent chromatin domains during cell fate decisions

por De Gobbi, Marco, Garrick, David, Lynch, Magnus, Vernimmen, Douglas, Hughes, Jim R, Goardon, Nicolas, Luc, Sidinh, Lower, Karen M, Sloane-Stanley, Jacqueline A, Pina, Cristina, Soneji, Shamit, Renella, Raffaele, Enver, Tariq, Taylor, Stephen, Jacobsen, Sten Eirik W, Vyas, Paresh, Gibbons, Richard J, Higgs, Douglas R
Publicado 2011

Mutant IDH1 Promotes Glioma Formation In Vivo

por Philip, Beatrice, Yu, Diana X., Silvis, Mark R., Shin, Clifford H., Robinson, James P., Robinson, Gemma L., Welker, Adam E., Angel, Stephanie N., Tripp, Sheryl R., Sonnen, Joshua A., VanBrocklin, Matthew W., Gibbons, Richard J., Looper, Ryan E., Colman, Howard, Holmen, Sheri L.
Publicado 2018

Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia

por Mettananda, Sachith, Fisher, Chris A., Hay, Deborah, Badat, Mohsin, Quek, Lynn, Clark, Kevin, Hublitz, Philip, Downes, Damien, Kerry, Jon, Gosden, Matthew, Telenius, Jelena, Sloane-Stanley, Jackie A., Faustino, Paula, Coelho, Andreia, Doondeea, Jessica, Usukhbayar, Batchimeg, Sopp, Paul, Sharpe, Jacqueline A., Hughes, Jim R., Vyas, Paresh, Gibbons, Richard J., Higgs, Douglas R.
Publicado 2017