A pharmacokinetic evaluation and metabolite identification of the GHB receptor antagonist NCS‐382 in mouse informs novel therapeutic strategies for the treatment of GHB intoxicatio...

por Ainslie, Garrett R., Gibson, K. Michael, Vogel, Kara R.
Publicado 2016

Aberrant GABA(A) Receptor-Mediated Inhibition in Cortico-Thalamic Networks of Succinic Semialdehyde Dehydrogenase Deficient Mice

por Errington, Adam C., Gibson, K. Michael, Crunelli, Vincenzo, Cope, David W.
Publicado 2011

Alveolar macrophage kinetics after inhalation of 239PuO2 by CBA/Ca mice: changes in synthesis of DNA.

por Kellington, J P, Gibson, K, Buckle, T M, Talbot, R J, Hornby, S B
Publicado 1992

Understanding the non-pharmacological correlates of self-reported efficacy of antidepressants

por Read, J, Gibson, K, Cartwright, C, Shiels, C, Dowrick, C, Gabbay, M
Publicado 2015

Comparative genomics of aldehyde dehydrogenase 5a1 (succinate semialdehyde dehydrogenase) and accumulation of gamma-hydroxybutyrate associated with its deficiency

por Malaspina, Patrizia, Picklo, Matthew J, Jakobs, C, Snead, O Carter, Gibson, K Michael
Publicado 2009

Neurotransmitter alterations in embryonic succinate semialdehyde dehydrogenase (SSADH) deficiency suggest a heightened excitatory state during development

por Jansen, Erwin EW, Struys, Eduard, Jakobs, Cornelis, Hager, Elizabeth, Snead, O Carter, Gibson, K Michael
Publicado 2008

Torin 1 partially corrects vigabatrin-induced mitochondrial increase in mouse

por Vogel, Kara R, Ainslie, Garrett R, Jansen, Erwin E W, Salomons, Gajja S, Gibson, K Michael
Publicado 2015

The impact of reclassification of C3 predominant glomerulopathies on diagnostic accuracy, outcome and prognosis in patients with C3 glomerulonephritis

por Puri, P., Walters, G. D., Fadia, M. N., Konia, M., Gibson, K. A., Jiang, S. H.
Publicado 2020

Brain–blood amino acid correlates following protein restriction in murine maple syrup urine disease

por Vogel, Kara R, Arning, Erland, Wasek, Brandi L, McPherson, Sterling, Bottiglieri, Teodoro, Gibson, K Michael
Publicado 2014

Longitudinal metabolomics in dried bloodspots yields profiles informing newborn screening for succinic semialdehyde dehydrogenase deficiency

por Brown, Madalyn, Turgeon, Coleman, Rinaldo, Piero, Pop, Ana, Salomons, Gajja S., Roullet, Jean‐Baptiste, Gibson, K. Michael
Publicado 2020

Defects in GABA metabolism affect selective autophagy pathways and are alleviated by mTOR inhibition

por Lakhani, Ronak, Vogel, Kara R, Till, Andreas, Liu, Jingjing, Burnett, Sarah F, Gibson, K Michael, Subramani, Suresh
Publicado 2014

In vitro modeling of experimental succinic semialdehyde dehydrogenase deficiency (SSADHD) using brain-derived neural stem cells

por Vogel, Kara R., Ainslie, Garrett R., Jansen, Erwin E., Salomons, Gajja S., Roullet, Jean-Baptiste, Gibson, K. Michael
Publicado 2017

Physiological competition of brain phenylalanine accretion: Initial pharmacokinetic analyses of aminoisobutyric and methylaminoisobutyric acids in Pah(enu2 −/−) mice

por Vogel, Kara R., Ainslie, Garrett R., Phillips, Brian, Arning, Erland, Bottiglieri, Teodoro, Shen, Danny D., Gibson, K. Michael
Publicado 2015

Novel Dual-Organelle-Targeting Probe (RCPP) for Simultaneous Measurement of Organellar Acidity and Alkalinity in Living Cells

por Yapici, Nazmiye B., Gao, Xiang, Yan, Xin, Hou, Shanshan, Jockusch, Steffen, Lesniak, Lillian, Gibson, K. Michael, Bi, Lanrong
Publicado 2021

Cellular and molecular outcomes of glutamine supplementation in the brain of succinic semialdehyde dehydrogenase‐deficient mice

por Brown, Madalyn N., Gibson, K. Michael, Schmidt, Michelle A., Walters, Dana C., Arning, Erland, Bottiglieri, Teodoro, Roullet, Jean‐Baptiste
Publicado 2020

Age‐related phenotype and biomarker changes in SSADH deficiency

por DiBacco, Melissa L., Roullet, Jean‐Baptiste, Kapur, Kush, Brown, Madalyn N., Walters, Dana C., Gibson, K. Michael, Pearl, Phillip L.
Publicado 2018

A new case of GABA transaminase deficiency facilitated by proton MR spectroscopy

por Tsuji, Megumi, Aida, Noriko, Obata, Takayuki, Tomiyasu, Moyoko, Furuya, Noritaka, Kurosawa, Kenji, Errami, Abdellatif, Gibson, K. Michael, Salomons, Gajja S., Jakobs, Cornelis, Osaka, Hitoshi
Publicado 2010

Indole Alkaloid Derivative B, a Novel Bifunctional Agent That Mitigates 5-Fluorouracil-Induced Cardiotoxicity

por Bi, Wei, Bi, Yue, Li, Pengfei, Hou, Shanshan, Yan, Xin, Hensley, Connor, Bammert, Catherine E., Zhang, Yanrong, Gibson, K. Michael, Ju, Jingfang, Bi, Lanrong
Publicado 2018

Preclinical tissue distribution and metabolic correlations of vigabatrin, an antiepileptic drug associated with potential use‐limiting visual field defects

por Walters, Dana C., Jansen, Erwin E. W., Ainslie, Garrett R., Salomons, Gajja S., Brown, Madalyn N., Schmidt, Michelle A., Roullet, Jean‐Baptiste, Gibson, K. M.
Publicado 2019

Lysosomal Targeting with Stable and Sensitive Fluorescent Probes (Superior LysoProbes): Applications for Lysosome Labeling and Tracking during Apoptosis

por Chen, Xin, Bi, Yue, Wang, Tianyang, Li, Pengfei, Yan, Xin, Hou, Shanshan, Bammert, Catherine E., Ju, Jingfang, Gibson, K. Michael, Pavan, William J., Bi, Lanrong
Publicado 2015