The RIDD activity of C. elegans IRE1 modifies neuroendocrine signaling in anticipation of environment stress to ensure survival

por Mingjie, Ying, Yair, Argon, Tali, Gidalevitz
Publicado 2023

A Bystander Mechanism Explains the Specific Phenotype of a Broadly Expressed Misfolded Protein

por Klabonski, Lauren, Zha, Ji, Senthilkumar, Lakshana, Gidalevitz, Tali
Publicado 2016

Destabilizing Protein Polymorphisms in the Genetic Background Direct Phenotypic Expression of Mutant SOD1 Toxicity

por Gidalevitz, Tali, Krupinski, Thomas, Garcia, Susana, Morimoto, Richard I.
Publicado 2009

HSP-4/BiP expression in secretory cells is regulated by a developmental program and not by the unfolded protein response

por Zha, Ji, Ying, Mingjie, Alexander-Floyd, Jasmine, Gidalevitz, Tali
Publicado 2019

Natural genetic variation determines susceptibility to aggregation or toxicity in a C. elegans model for polyglutamine disease

por Gidalevitz, Tali, Wang, Ning, Deravaj, Tanuja, Alexander-Floyd, Jasmine, Morimoto, Richard I
Publicado 2013

Unexpected cell type-dependent effects of autophagy on polyglutamine aggregation revealed by natural genetic variation in C. elegans

por Alexander-Floyd, J., Haroon, S., Ying, M., Entezari, A. A., Jaeger, C., Vermulst, M., Gidalevitz, T.
Publicado 2020

Increased activity of IRE1 improves the clinical presentation of EAE

por Bracchi-Ricard, Valerie, Nguyen, Kayla, Ricci, Daniela, Gaudette, Brian, Henao-Meija, Jorge, Brambilla, Roberta, Martynyuk, Tetyana, Gidalevitz, Tali, Allman, David, Bethea, John R., Argon, Yair
Publicado 2023

Multiple Molecular Mechanisms Rescue mtDNA Disease in C. elegans

por Haroon, Suraiya, Li, Annie, Weinert, Jaye L., Fritsch, Clark, Ericson, Nolan G., Alexander-Floyd, Jasmine, Braeckman, Bart P., Haynes, Cole M., Bielas, Jason H., Gidalevitz, Tali, Vermulst, Marc
Publicado 2018

HspB1 Overexpression Improves Life Span and Stress Resistance in an Invertebrate Model

por Alexander, Courtney Carroll, Munkáscy, Erin, Tillmon, Haven, Fraker, Tamara, Scheirer, Jessica, Holstein, Deborah, Lozano, Damian, Khan, Maruf, Gidalevitz, Tali, Lechleiter, James D, Fisher, Alfred L, Zare, Habil, Rodriguez, Karl A
Publicado 2021

An interdomain helix in IRE1α mediates the conformational change required for the sensor's activation

por Ricci, Daniela, Tutton, Stephen, Marrocco, Ilaria, Ying, Mingjie, Blumenthal, Daniel, Eletto, Daniela, Vargas, Jade, Boyle, Sarah, Fazelinia, Hossein, Qian, Lei, Suresh, Krishna, Taylor, Deanne, Paton, James C., Paton, Adrienne W., Tang, Chih-Hang Anthony, Hu, Chih-Chi Andrew, Radhakrishnan, Ravi, Gidalevitz, Tali, Argon, Yair
Publicado 2021