Synthetic studies towards isomeric pyrazolopyrimidines as potential ATP synthesis inhibitors of Mycobacterium tuberculosis. Structural correction of reported N-(6-(2-(dimethylamino...

por Choi, Peter J., Lu, Guo-Liang, Sutherland, Hamish S., Giddens, Anna C., Franzblau, Scott G., Cooper, Christopher B., Denny, William A., Palmer, Brian D.
Publicado 2022

Synthesis and Structure–Activity Relationships for the Anti-Mycobacterial Activity of 3-Phenyl-N-(Pyridin-2-ylmethyl)Pyrazolo[1,5-a]Pyrimidin-7-Amines

por Sutherland, Hamish S., Choi, Peter J., Lu, Guo-Liang, Giddens, Anna C., Tong, Amy S. T., Franzblau, Scott G., Cooper, Christopher B., Palmer, Brian D., Denny, William A.
Publicado 2022

Biological characterization of SN32976, a selective inhibitor of PI3K and mTOR with preferential activity to PI3Kα, in comparison to established pan PI3K inhibitors

por Rewcastle, Gordon W, Kolekar, Sharada, Buchanan, Christina M, Gamage, Swarna A, Giddens, Anna C, Tsang, Kit Y, Kendall, Jackie D, Singh, Ripudaman, Lee, Woo-Jeong, Smith, Greg C, Han, Weiping, Matthews, David J, Denny, William A, Shepherd, Peter R, Jamieson, Stephen M.F
Publicado 2017