An efficient and versatile CRISPR-Cas9 system for genetic manipulation of multi-drug resistant Klebsiella pneumoniae

por McConville, Thomas H., Giddins, Marla J., Uhlemann, Anne-Catrin
Publicado 2021

Preclinical Antimalarial Combination Study of M5717, a Plasmodium falciparum Elongation Factor 2 Inhibitor, and Pyronaridine, a Hemozoin Formation Inhibitor

por Rottmann, Matthias, Jonat, Brian, Gumpp, Christin, Dhingra, Satish K., Giddins, Marla J., Yin, Xiaoyan, Badolo, Lassina, Greco, Beatrice, Fidock, David A., Oeuvray, Claude, Spangenberg, Thomas
Publicado 2020

Barrett’s esophagus is associated with a distinct oral microbiome

por Snider, Erik J., Compres, Griselda, Freedberg, Daniel E., Giddins, Marla J., Khiabanian, Hossein, Lightdale, Charles J., Nobel, Yael R., Toussaint, Nora C., Uhlemann, Anne-Catrin, Abrams, Julian A.
Publicado 2018

Genomic and Epidemiological Features of Two Dominant Methicillin-Susceptible Staphylococcus aureus Clones from a Neonatal Intensive Care Unit Surveillance Effort

por Annavajhala, Medini K., Kelly, Nicole E., Geng, Wenjing, Ferguson, Samantha A., Giddins, Marla J., Grohs, Emily C., Hill-Ricciuti, Alexandra, Green, Daniel A., Saiman, Lisa, Uhlemann, Anne-Catrin
Publicado 2022

Genomic and Geographic Context for the Evolution of High-Risk Carbapenem-Resistant Enterobacter cloacae Complex Clones ST171 and ST78

por Gomez-Simmonds, Angela, Annavajhala, Medini K., Wang, Zheng, Macesic, Nenad, Hu, Yue, Giddins, Marla J., O’Malley, Aidan, Toussaint, Nora C., Whittier, Susan, Torres, Victor J., Uhlemann, Anne-Catrin
Publicado 2018

CrrB Positively Regulates High-Level Polymyxin Resistance and Virulence in Klebsiella pneumoniae

por McConville, Thomas H., Annavajhala, Medini K., Giddins, Marla J., Macesic, Nenad, Herrera, Carmen M., Rozenberg, Felix D., Bhushan, Gitanjali L., Ahn, Danielle, Mancia, Filippo, Trent, M. Stephen, Uhlemann, Anne-Catrin
Publicado 2020

Colonizing multidrug-resistant bacteria and the longitudinal evolution of the intestinal microbiome after liver transplantation

por Annavajhala, Medini K., Gomez-Simmonds, Angela, Macesic, Nenad, Sullivan, Sean B., Kress, Anna, Khan, Sabrina D., Giddins, Marla J., Stump, Stephania, Kim, Grace I., Narain, Ryan, Verna, Elizabeth C., Uhlemann, Anne-Catrin
Publicado 2019

Safety, pharmacokinetics, and antimalarial activity of the novel plasmodium eukaryotic translation elongation factor 2 inhibitor M5717: a first-in-human, randomised, placebo-contro...

por McCarthy, James S, Yalkinoglu, Özkan, Odedra, Anand, Webster, Rebecca, Oeuvray, Claude, Tappert, Aliona, Bezuidenhout, Deon, Giddins, Marla J, Dhingra, Satish K, Fidock, David A, Marquart, Louise, Webb, Lachlan, Yin, Xiaoyan, Khandelwal, Akash, Bagchus, Wilhelmina M
Publicado 2021

Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity

por Vanaerschot, Manu, Murithi, James M., Pasaje, Charisse Flerida A., Ghidelli-Disse, Sonja, Dwomoh, Louis, Bird, Megan, Spottiswoode, Natasha, Mittal, Nimisha, Arendse, Lauren B., Owen, Edward S., Wicht, Kathryn J., Siciliano, Giulia, Bösche, Markus, Yeo, Tomas, Kumar, T.R. Santha, Mok, Sachel, Carpenter, Emma F., Giddins, Marla J., Sanz, Olalla, Ottilie, Sabine, Alano, Pietro, Chibale, Kelly, Llinás, Manuel, Uhlemann, Anne-Catrin, Delves, Michael, Tobin, Andrew B., Doerig, Christian, Winzeler, Elizabeth A., Lee, Marcus C.S., Niles, Jacquin C., Fidock, David A.
Publicado 2020