Identification of IFN-γ-producing T cells as the main mediators of the side effects associated to mouse interleukin-15 sustained exposure

por Scala, Marianna Di, Gil-Fariña, Irene, Olagüe, Cristina, Vales, Africa, Sobrevals, Luciano, Fortes, Puri, Corbacho, David, González-Aseguinolaza, Gloria
Publicado 2016

IL12-Mediated Liver Inflammation Reduces the Formation of AAV Transcriptionally Active Forms but Has No Effect over Preexisting AAV Transgene Expression

por Gil-Fariña, Irene, Di Scala, Marianna, Vanrell, Lucia, Olagüe, Cristina, Vales, Africa, High, Katherine A., Prieto, Jesus, Mingozzi, Federico, Gonzalez-Aseguinolaza, Gloria
Publicado 2013

Complementary Effects of Interleukin-15 and Alpha Interferon Induce Immunity in Hepatitis B Virus Transgenic Mice

por Di Scala, Marianna, Otano, Itziar, Gil-Fariña, Irene, Vanrell, Lucia, Hommel, Mirja, Olagüe, Cristina, Vales, Africa, Galarraga, Miguel, Guembe, Laura, Ortiz de Solorzano, Carlos, Ghosh, Indrajit, Maini, Mala K., Prieto, Jesús, González-Aseguinolaza, Gloria
Publicado 2016

Longitudinal analyses of CLL in mice identify leukemia-related clonal changes including a Myc gain predicting poor outcome in patients

por Öztürk, Selcen, Paul, Yashna, Afzal, Saira, Gil-Farina, Irene, Jauch, Anna, Bruch, Peter-Martin, Kalter, Verena, Hanna, Bola, Arseni, Lavinia, Roessner, Philipp M., Schmidt, Manfred, Stilgenbauer, Stephan, Dietrich, Sascha, Lichter, Peter, Zapatka, Marc, Seiffert, Martina
Publicado 2021

In Utero Transfer of Adeno-Associated Viral Vectors Produces Long-Term Factor IX Levels in a Cynomolgus Macaque Model

por Mattar, Citra N.Z., Gil-Farina, Irene, Rosales, Cecilia, Johana, Nuryanti, Tan, Yvonne Yi Wan, McIntosh, Jenny, Kaeppel, Christine, Waddington, Simon N., Biswas, Arijit, Choolani, Mahesh, Schmidt, Manfred, Nathwani, Amit C., Chan, Jerry K.Y.
Publicado 2017

Therapeutic expression of human clotting factors IX and X following adeno-associated viral vector–mediated intrauterine gene transfer in early-gestation fetal macaques

por Chan, Jerry K. Y., Gil-Farina, Irene, Johana, Nuryanti, Rosales, Cecilia, Tan, Yi Wan, Ceiler, Jessika, Mcintosh, Jenny, Ogden, Bryan, Waddington, Simon N., Schmidt, Manfred, Biswas, Arijit, Choolani, Mahesh, Nathwani, Amit C., Mattar, Citra N. Z.
Publicado 2019

Evaluating the state of the science for adeno-associated virus integration: An integrated perspective

por Sabatino, Denise E., Bushman, Frederic D., Chandler, Randy J., Crystal, Ronald G., Davidson, Beverly L., Dolmetsch, Ricardo, Eggan, Kevin C., Gao, Guangping, Gil-Farina, Irene, Kay, Mark A., McCarty, Douglas M., Montini, Eugenio, Ndu, Adora, Yuan, Jing
Publicado 2022

HIV- 1 lentivirus tethering to the genome is associated with transcription factor binding sites found in genes that favour virus survival

por Suleman, Saqlain, Payne, Annette, Bowden, Johnathan, Haque, Sharmin Al, Zahn, Marco, Fawaz, Serena, Khalifa, Mohammad S., Jobling, Susan, Hay, David, Franco, Matteo, Fronza, Raffaele, Wang, Wei, Strobel-Freidekind, Olga, Deichmann, Annette, Takeuchi, Yasuhiro, Waddington, Simon N., Gil-Farina, Irene, Schmidt, Manfred, Themis, Michael
Publicado 2022

Partial correction of immunodeficiency by lentiviral vector gene therapy in mouse models carrying Rag1 hypomorphic mutations

por Castiello, Maria Carmina, Di Verniere, Martina, Draghici, Elena, Fontana, Elena, Penna, Sara, Sereni, Lucia, Zecchillo, Alessandra, Minuta, Denise, Uva, Paolo, Zahn, Marco, Gil-Farina, Irene, Annoni, Andrea, Iaia, Silvia, Ott de Bruin, Lisa M., Notarangelo, Luigi D., Pike-Overzet, Karin, Staal, Frank J. T., Villa, Anna, Capo, Valentina
Publicado 2023

Comprehensive genomic characterization of gene therapy-induced T-cell acute lymphoblastic leukemia

por Horak, Peter, Uhrig, Sebastian, Witzel, Maximilian, Gil-Farina, Irene, Hutter, Barbara, Rath, Tim, Gieldon, Laura, Balasubramanian, Gnana Prakash, Pastor, Xavier, Heilig, Christoph E., Richter, Daniela, Schröck, Evelin, Ball, Claudia R., Brors, Benedikt, Braun, Christian J., Albert, Michael H., Scholl, Claudia, von Kalle, Christof, Schmidt, Manfred, Fröhling, Stefan, Klein, Christoph, Glimm, Hanno
Publicado 2020

Publisher Correction: Comprehensive genomic characterization of gene therapy-induced T-cell acute lymphoblastic leukemia

por Horak, Peter, Uhrig, Sebastian, Witzel, Maximilian, Gil-Farina, Irene, Hutter, Barbara, Rath, Tim, Gieldon, Laura, Balasubramanian, Gnana Prakash, Pastor, Xavier, Heilig, Christoph E., Richter, Daniela, Schröck, Evelin, Ball, Claudia R., Brors, Benedikt, Braun, Christian J., Albert, Michael H., Scholl, Claudia, von Kalle, Christof, Schmidt, Manfred, Fröhling, Stefan, Klein, Christoph, Glimm, Hanno
Publicado 2021