Nonclinical Safety Profile of Revusiran, a 1st-Generation GalNAc-siRNA Conjugate for Treatment of Hereditary Transthyretin-Mediated Amyloidosis

por Sutherland, Jessica E., Hettinger, Julia L., Chan, Amy, Gilbert, Jason, Warner, Garvin L., Davis, Wendell P.
Publicado 2020

A study of Indiana University Health's spirit of inquiry and innovation during COVID

por Carpenter, Janet S., Draucker, Claire B., Ellis, Rebecca J. Bartlett, Ferren, Melora D., Gilbert, Jason H., Newhouse, Robin P., Von Ah, Diane
Publicado 2022

Neurofilament Light Chain as a Biomarker of Hereditary Transthyretin-Mediated Amyloidosis

por Ticau, Simina, Sridharan, Gautham V., Tsour, Shira, Cantley, William L., Chan, Amy, Gilbert, Jason A., Erbe, David, Aldinc, Emre, Reilly, Mary M., Adams, David, Polydefkis, Michael, Fitzgerald, Kevin, Vaishnaw, Akshay, Nioi, Paul
Publicado 2021

Role of a “Magic” Methyl: 2′-Deoxy-2′-α-F-2′-β-C-methyl Pyrimidine Nucleotides Modulate RNA Interference Activity through Synergy with 5′-Phosphate Mimics and Mitigation of Off-Tar...

por Guenther, Dale C., Mori, Shohei, Matsuda, Shigeo, Gilbert, Jason A., Willoughby, Jennifer L. S., Hyde, Sarah, Bisbe, Anna, Jiang, Yongfeng, Agarwal, Saket, Madaoui, Mimouna, Janas, Maja M., Charisse, Klaus, Maier, Martin A., Egli, Martin, Manoharan, Muthiah
Publicado 2022

siRNAs containing 2′-fluorinated Northern-methanocarbacyclic (2′-F-NMC) nucleotides: in vitro and in vivo RNAi activity and inability of mitochondrial polymerases to incorporate 2′...

por Akabane-Nakata, Masaaki, Erande, Namrata D, Kumar, Pawan, Degaonkar, Rohan, Gilbert, Jason A, Qin, June, Mendez, Martha, Woods, Lauren Blair, Jiang, Yongfeng, Janas, Maja M, O’Flaherty, Derek K, Zlatev, Ivan, Schlegel, Mark K, Matsuda, Shigeo, Egli, Martin, Manoharan, Muthiah
Publicado 2021

Sepsis-induced cardiomyopathy is associated with higher mortality rates in patients with sepsis

por Hanumanthu, Balaram Krishna J, Nair, Anika Sasidharan, Katamreddy, Adarsh, Gilbert, Jason S, You, Jee Young, Offor, Obiageli Lynda, Kushwaha, Ankit, Krishnan, Ankita, Napolitano, Marzio, Palaidimos, Leonidas, Morante, Joaquin, Tekwani, Seema S., Mehta, Suchita, Gupta, Aanchal, Goraya, Harmeen, Sun, Mengyang, Faillace, Robert T., Gulani, Perminder
Publicado 2021