Codon optimality in cancer

por Gillen, Sarah L., Waldron, Joseph A., Bushell, Martin
Publicado 2021

Differential regulation of mRNA fate by the human Ccr4-Not complex is driven by coding sequence composition and mRNA localization

por Gillen, Sarah L., Giacomelli, Chiara, Hodge, Kelly, Zanivan, Sara, Bushell, Martin, Wilczynska, Ania
Publicado 2021

Optimisation of Sample Preparation from Primary Mouse Tissue to Maintain RNA Integrity for Methods Examining Translational Control

por Munro, June, Gillen, Sarah L., Mitchell, Louise, Laing, Sarah, Karim, Saadia A., Rink, Curtis J., Waldron, Joseph A., Bushell, Martin
Publicado 2023

The proneural transcription factor ASCL1 regulates cell proliferation and primes for differentiation in neuroblastoma

por Parkinson, Lydia M., Gillen, Sarah L., Woods, Laura M., Chaytor, Lewis, Marcos, Daniel, Ali, Fahad R., Carroll, Jason S., Philpott, Anna
Publicado 2022

DEAD-box helicase eIF4A2 inhibits CNOT7 deadenylation activity

por Meijer, Hedda A, Schmidt, Tobias, Gillen, Sarah L, Langlais, Claudia, Jukes-Jones, Rebekah, de Moor, Cornelia H, Cain, Kelvin, Wilczynska, Ania, Bushell, Martin
Publicado 2019

mRNA structural elements immediately upstream of the start codon dictate dependence upon eIF4A helicase activity

por Waldron, Joseph A., Tack, David C., Ritchey, Laura E., Gillen, Sarah L., Wilczynska, Ania, Turro, Ernest, Bevilacqua, Philip C., Assmann, Sarah M., Bushell, Martin, Le Quesne, John
Publicado 2019

eIF4A2 drives repression of translation at initiation by Ccr4-Not through purine-rich motifs in the 5′UTR

por Wilczynska, Ania, Gillen, Sarah L., Schmidt, Tobias, Meijer, Hedda A., Jukes-Jones, Rebekah, Langlais, Claudia, Kopra, Kari, Lu, Wei-Ting, Godfrey, Jack D., Hawley, Benjamin R., Hodge, Kelly, Zanivan, Sara, Cain, Kelvin, Le Quesne, John, Bushell, Martin
Publicado 2019