Comparative Analyses of Liquid-Biopsy MicroRNA371a-3p Isolation Protocols for Serum and Plasma

por Timmerman, Dennis M., Gillis, Ad J. M., Mego, Michal, Looijenga, Leendert H. J.
Publicado 2021

Human Germ Cell Tumors are Developmental Cancers: Impact of Epigenetics on Pathobiology and Clinic

por Lobo, João, Gillis, Ad J. M., Jerónimo, Carmen, Henrique, Rui, Looijenga, Leendert H. J.
Publicado 2019

Prediction of relapse in stage I testicular germ cell tumor patients on surveillance: investigation of biomarkers

por Lobo, João, Gillis, Ad J. M., van den Berg, Annette, Looijenga, Leendert H. J.
Publicado 2020

VASA mRNA (DDX4) detection is more specific than immunohistochemistry using poly- or monoclonal antibodies for germ cells in the male urogenital tract

por Boellaard, Willem P.A., Stoop, Hans, Gillis, Ad J.M., Oosterhuis, J. Wolter., Looijenga, Leendert H.J.
Publicado 2017

Role of SOX2 in the Etiology of Embryonal Carcinoma, Based on Analysis of the NCCIT and NT2 Cell Lines

por Eini, Ronak, Stoop, Hans, Gillis, Ad J. M., Biermann, Katharina, Dorssers, Lambert C. J., Looijenga, Leendert H. J.
Publicado 2014

CRIPTO and miR-371a-3p Are Serum Biomarkers of Testicular Germ Cell Tumors and Are Detected in Seminal Plasma from Azoospermic Males

por Spiller, Cassy M., Lobo, João, Boellaard, Willem P. A., Gillis, Ad J. M., Bowles, Josephine, Looijenga, Leendert H. J.
Publicado 2020

Humanised Mice and Immunodeficient Mice (NSG) Are Equally Sensitive for Prediction of Stem Cell Malignancy in the Teratoma Assay

por Bialecka, Monika, Montilla-Rojo, Joaquin, Roelen, Bernard A. J., Gillis, Ad J., Looijenga, Leendert H. J., Salvatori, Daniela. C. F.
Publicado 2022

The Role of TP53 in Cisplatin Resistance in Mediastinal and Testicular Germ Cell Tumors

por Timmerman, Dennis M., Eleveld, Thomas F., Gillis, Ad J. M., Friedrichs, Carlijn C., Hillenius, Sanne, Remmers, Tessa L., Sriram, Sruthi, Looijenga, Leendert H. J.
Publicado 2021

Genome Wide DNA Methylation Profiles Provide Clues to the Origin and Pathogenesis of Germ Cell Tumors

por Rijlaarsdam, Martin A., Tax, David M. J., Gillis, Ad J. M., Dorssers, Lambert C. J., Koestler, Devin C., de Ridder, Jeroen, Looijenga, Leendert H. J.
Publicado 2015

Combining Hypermethylated RASSF1A Detection Using ddPCR with miR-371a-3p Testing: An Improved Panel of Liquid Biopsy Biomarkers for Testicular Germ Cell Tumor Patients

por Lobo, João, van Zogchel, Lieke M. J., Nuru, Mohammed G., Gillis, Ad J. M., van der Schoot, C. Ellen, Tytgat, Godelieve A. M., Looijenga, Leendert H. J.
Publicado 2021

A pipeline to quantify serum and cerebrospinal fluid microRNAs for diagnosis and detection of relapse in paediatric malignant germ-cell tumours

por Murray, Matthew J, Bell, Emma, Raby, Katie L, Rijlaarsdam, Martin A, Gillis, Ad J M, Looijenga, Leendert H J, Brown, Helen, Destenaves, Benoit, Nicholson, James C, Coleman, Nicholas
Publicado 2016

XIST-Promoter Demethylation as Tissue Biomarker for Testicular Germ Cell Tumors and Spermatogenesis Quality

por Lobo, João, Nunes, Sandra P., Gillis, Ad J. M., Barros-Silva, Daniela, Miranda-Gonçalves, Vera, van den Berg, Annette, Cantante, Mariana, Guimarães, Rita, Henrique, Rui, Jerónimo, Carmen, Looijenga, Leendert H. J.
Publicado 2019

Analysis of a mouse germ cell tumor model establishes pluripotency-associated miRNAs as conserved serum biomarkers for germ cell cancer detection

por Loehr, Amanda R., Timmerman, Dennis M., Liu, Michelle, Gillis, Ad J.M., Matthews, Melia, Bloom, Jordana C., Nicholls, Peter K., Page, David C., Miller, Andrew D., Looijenga, Leendert H.J., Weiss, Robert S.
Publicado 2023

Whole-genome sequencing of spermatocytic tumors provides insights into the mutational processes operating in the male germline

por Giannoulatou, Eleni, Maher, Geoffrey J., Ding, Zhihao, Gillis, Ad J. M., Dorssers, Lambert C. J., Hoischen, Alexander, Rajpert-De Meyts, Ewa, McVean, Gilean, Wilkie, Andrew O. M., Looijenga, Leendert H. J., Goriely, Anne
Publicado 2017

The MicroRNA-371 Family as Plasma Biomarkers for Monitoring Undifferentiated and Potentially Malignant Human Pluripotent Stem Cells in Teratoma Assays

por Salvatori, Daniela C.F., Dorssers, Lambert C.J., Gillis, Ad J.M., Perretta, Gemma, van Agthoven, Ton, Gomes Fernandes, Maria, Stoop, Hans, Prins, Jan-Bas, Oosterhuis, J. Wolter, Mummery, Christine, Looijenga, Leendert H.J.
Publicado 2018

Seminoma and Embryonal Carcinoma Footprints Identified by Analysis of Integrated Genome-Wide Epigenetic and Expression Profiles of Germ Cell Cancer Cell Lines

por van der Zwan, Yvonne G., Rijlaarsdam, Martin A., Rossello, Fernando J., Notini, Amanda J., de Boer, Suzan, Watkins, D. Neil, Gillis, Ad J. M., Dorssers, Lambert C. J., White, Stefan J., Looijenga, Leendert H. J.
Publicado 2014

Molecular heterogeneity and early metastatic clone selection in testicular germ cell cancer development

por Dorssers, Lambert C. J., Gillis, Ad J. M., Stoop, Hans, van Marion, Ronald, Nieboer, Marleen M., van Riet, Job, van de Werken, Harmen J. G., Oosterhuis, J. Wolter, de Ridder, Jeroen, Looijenga, Leendert H. J.
Publicado 2019

Paclitaxel, Ifosfamide, and Cisplatin in Patients with Poor-prognosis Disseminated Nonseminomatous Germ Cell Tumors with Unfavorable Serum Tumor Marker Decline After First Cycle of...

por Mego, Michal, Rejlekova, Katarina, Svetlovska, Daniela, Miskovska, Vera, Gillis, Ad J.M., De Angelis, Valentina, Kalavska, Katarina, Obertova, Jana, Palacka, Patrik, Reckova, Maria, Sycova-Mila, Zuzana, Pindak, Daniel, Chovanec, Michal, Looijenga, Leendert H.J., Mardiak, Jozef
Publicado 2021

Chromosome 3p25.3 Gain Is Associated With Cisplatin Resistance and Is an Independent Predictor of Poor Outcome in Male Malignant Germ Cell Tumors

por Timmerman, Dennis M., Eleveld, Thomas F., Sriram, Sruthi, Dorssers, Lambert C.J., Gillis, Ad J.M., Schmidtova, Silvia, Kalavska, Katarina, van de Werken, Harmen J.G., Oing, Christoph, Honecker, Friedemann, Mego, Michal, Looijenga, Leendert H.J.
Publicado 2022

Napabucasin overcomes cisplatin resistance in ovarian germ cell tumor-derived cell line by inhibiting cancer stemness

por Schmidtova, Silvia, Dorssers, Lambert C. J., Kalavska, Katarina, Gillis, Ad J. M., Oosterhuis, J. Wolter, Stoop, Hans, Miklikova, Svetlana, Kozovska, Zuzana, Burikova, Monika, Gercakova, Katarina, Durinikova, Erika, Chovanec, Michal, Mego, Michal, Kucerova, Lucia, Looijenga, Leendert H. J.
Publicado 2020