RAS: Striking at the Core of the Oncogenic Circuitry

por Gimple, Ryan C., Wang, Xiuxing
Publicado 2019

Editorial: Epigenetic and metabolic regulation of primary and metastatic brain cancers

por Gimple, Ryan C., Prager, Briana C., Xie, Qi
Publicado 2023

Glioblastoma stem cells: lessons from the tumor hierarchy in a lethal cancer

por Gimple, Ryan C., Bhargava, Shruti, Dixit, Deobrat, Rich, Jeremy N.
Publicado 2019

Plasma cells shape the mesenchymal identity of ovarian cancers through transfer of exosome-derived microRNAs

por Yang, Zhengnan, Wang, Wei, Zhao, Linjie, Wang, Xin, Gimple, Ryan C., Xu, Lian, Wang, Yuan, Rich, Jeremy N., Zhou, Shengtao
Publicado 2021

“Reprogram Enablement” as an Assay for Identifying Early Oncogenic Pathways by Their Ability to Allow Neoplastic Cells to Reacquire an Epiblast State

por Kong, Yanjun, Gimple, Ryan C., McVicar, Rachael N., Hodges, Andrew P., Yin, Jun, Liu, Yang, Zhan, Weiwei, Snyder, Evan Y.
Publicado 2020

Adipocytes promote breast tumorigenesis through TAZ-dependent secretion of Resistin

por Gao, Yuhao, Chen, Xiaosong, He, Qing, Gimple, Ryan C., Liao, Yajin, Wang, Liang, Wu, Rong, Xie, Qi, Rich, Jeremy N., Shen, Kunwei, Yuan, Zengqiang
Publicado 2020

Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling

por Lee, Derrick, Gimple, Ryan C., Wu, Xujia, Prager, Briana C., Qiu, Zhixin, Wu, Qiulian, Daggubati, Vikas, Mariappan, Aruljothi, Gopalakrishnan, Jay, Sarkisian, Matthew R., Raleigh, David R., Rich, Jeremy N.
Publicado 2023

FSMP-08. TARGETING PYRIMIDINE SYNTHESIS ACCENTUATES MOLECULAR THERAPY RESPONSE IN GLIOBLASTOMA STEM CELLS

por Yang, Kailin, Wang, Xiuxing, Wu, Qiulian, Kim, Leo, Morton, Andrew, Gimple, Ryan, Prager, Briana, Tao, Weiwei, Qiu, Zhixin, Zhao, Linjie, Agnihotri, Sameer, Mischel, Paul, Mack, Stephen, Bao, Shideng, Rich, Jeremy
Publicado 2021

Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase

por Xia, Zhen, Tang, Min, Ma, Jiayan, Zhang, Hongyan, Gimple, Ryan C, Prager, Briana C, Tang, Hongzhen, Sun, Chongran, Liu, Fuyi, Lin, Peng, Mei, Yutang, Du, Ruoxin, Rich, Jeremy N, Xie, Qi
Publicado 2021

ADAR1-mediated RNA editing links ganglioside catabolism to glioblastoma stem cell maintenance

por Jiang, Li, Hao, Yajing, Shao, Changwei, Wu, Qiulian, Prager, Briana C., Gimple, Ryan C., Sulli, Gabriele, Kim, Leo J.Y., Zhang, Guoxin, Qiu, Zhixin, Zhu, Zhe, Fu, Xiang-Dong, Rich, Jeremy N.
Publicado 2022

Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma

por Sen, Arko, Prager, Briana C., Zhong, Cuiqing, Park, Donglim, Zhu, Zhe, Gimple, Ryan C., Wu, Qiulian, Bernatchez, Jean A., Beck, Sungjun, Clark, Alex E., Siqueira-Neto, Jair L., Rich, Jeremy N., McVicker, Graham
Publicado 2022

Distinct Epigenetic Effects of Tobacco Smoking in Whole Blood and among Leukocyte Subtypes

por Su, Dan, Wang, Xuting, Campbell, Michelle R., Porter, Devin K., Pittman, Gary S., Bennett, Brian D., Wan, Ma, Englert, Neal A., Crowl, Christopher L., Gimple, Ryan N., Adamski, Kelly N., Huang, Zhiqing, Murphy, Susan K., Bell, Douglas A.
Publicado 2016

Correction: Distinct Epigenetic Effects of Tobacco Smoking in Whole Blood and among Leukocyte Subtypes

por Su, Dan, Wang, Xuting, Campbell, Michelle R., Porter, Devin K., Pittman, Gary S., Bennett, Brian D., Wan, Ma, Englert, Neal A., Crowl, Christopher L., Gimple, Ryan C., Adamski, Kelly N., Huang, Zhiqing, Murphy, Susan K., Bell, Douglas A.
Publicado 2017

Pharmacological Activation of Estrogen Receptor Beta Overcomes Tumor Resistance to Immune Checkpoint Blockade Therapy

por Huang, Shuang, Zhou, Nianxin, Zhao, Linjie, Gimple, Ryan C., Ahn, Young Ha, Zhang, Peidong, Wang, Wei, Shao, Bin, Yang, Jingyun, Zhang, Qian, Zhao, Sai, Jiang, Xuehan, Chen, Zhiwei, Zeng, Yangfan, Hu, Hongbo, Gustafsson, Jan-Åke, Zhou, Shengtao
Publicado 2020

LncRNA INHEG promotes glioma stem cell maintenance and tumorigenicity through regulating rRNA 2’-O-methylation

por Liu, Lihui, Liu, Ziyang, Liu, Qinghua, Wu, Wei, Lin, Peng, Liu, Xing, Zhang, Yuechuan, Wang, Dongpeng, Prager, Briana C., Gimple, Ryan C., Yu, Jichuan, Zhao, Weixi, Wu, Qiulian, Zhang, Wei, Wu, Erzhong, Chen, Xiaomin, Luo, Jianjun, Rich, Jeremy N., Xie, Qi, Jiang, Tao, Chen, Runsheng
Publicado 2023

Targeting Glioma Stem Cells through Combined BMI1 and EZH2 Inhibition

por Jin, Xun, Kim, Leo J. Y., Wu, Qiulian, Wallace, Lisa C., Prager, Briana C., Sanvoranart, Tanwarat, Gimple, Ryan C., Wang, Xiuxing, Mack, Stephen C., Miller, Tyler E., Huang, Ping, Valentim, Claudia L., Zhou, Qi-gang, Barnholtz-Sloan, Jill S., Bao, Shideng, Sloan, Andrew E., Rich, Jeremy N.
Publicado 2017

Sorting nexin 10 sustains PDGF receptor signaling in glioblastoma stem cells via endosomal protein sorting

por Gimple, Ryan C., Zhang, Guoxin, Wang, Shuai, Huang, Tengfei, Lee, Jina, Taori, Suchet, Lv, Deguan, Dixit, Deobrat, Halbert, Matthew E., Morton, Andrew R., Kidwell, Reilly L., Dong, Zhen, Prager, Briana C., Kim, Leo J.Y., Qiu, Zhixin, Zhao, Linjie, Xie, Qi, Wu, Qiulian, Agnihotri, Sameer, Rich, Jeremy N.
Publicado 2023

Targeting EYA2 tyrosine phosphatase activity in glioblastoma stem cells induces mitotic catastrophe

por Zhang, Guoxin, Dong, Zhen, Gimple, Ryan C., Wolin, Arthur, Wu, Qiulian, Qiu, Zhixin, Wood, Lisa M., Shen, Jia Z., Jiang, Li, Zhao, Linjie, Lv, Deguan, Prager, Briana C., Kim, Leo J.Y., Wang, Xiuxing, Zhang, Lingdi, Anderson, Ryan L., Moore, Jeffrey K., Bao, Shideng, Keller, Thomas H., Lin, Grace, Kang, Congbao, Hamerlik, Petra, Zhao, Rui, Ford, Heide L., Rich, Jeremy N.
Publicado 2021

Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug

por Bi, Junfeng, Khan, Atif, Tang, Jun, Armando, Aaron M., Wu, Sihan, Zhang, Wei, Gimple, Ryan C., Reed, Alex, Jing, Hui, Koga, Tomoyuki, Wong, Ivy Tsz-Lo, Gu, Yuchao, Miki, Shunichiro, Yang, Huijun, Prager, Briana, Curtis, Ellis J., Wainwright, Derek A., Furnari, Frank B., Rich, Jeremy N., Cloughesy, Timothy F., Kornblum, Harley I., Quehenberger, Oswald, Rzhetsky, Andrey, Cravatt, Benjamin F., Mischel, Paul S.
Publicado 2021

Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions

por Tang, Min, Xie, Qi, Gimple, Ryan C., Zhong, Zheng, Tam, Trevor, Tian, Jing, Kidwell, Reilly L., Wu, Qiulian, Prager, Briana C., Qiu, Zhixin, Yu, Aaron, Zhu, Zhe, Mesci, Pinar, Jing, Hui, Schimelman, Jacob, Wang, Pengrui, Lee, Derrick, Lorenzini, Michael H., Dixit, Deobrat, Zhao, Linjie, Bhargava, Shruti, Miller, Tyler E., Wan, Xueyi, Tang, Jing, Sun, Bingjie, Cravatt, Benjamin F., Muotri, Alysson R., Chen, Shaochen, Rich, Jeremy N.
Publicado 2020