p75(NTR) in Huntington's disease: beyond the basal ganglia

por Brito, Verónica, Ginés, Silvia
Publicado 2015

A selective inhibitor of histone deacetylase 3 prevents cognitive deficits and suppresses striatal CAG repeat expansions in Huntington’s disease mice

por Suelves, Nuria, Kirkham-McCarthy, Lucy, Lahue, Robert S., Ginés, Silvia
Publicado 2017

Reversal of a full-length mutant huntingtin neuronal cell phenotype by chemical inhibitors of polyglutamine-mediated aggregation

por Wang, Jin, Gines, Silvia, MacDonald, Marcy E, Gusella, James F
Publicado 2005

CD200 is up-regulated in R6/1 transgenic mouse model of Huntington's disease

por Comella Bolla, Andrea, Valente, Tony, Miguez, Andres, Brito, Veronica, Gines, Silvia, Solà, Carme, Straccia, Marco, Canals, Josep M.
Publicado 2019

Synaptic RTP801 contributes to motor-learning dysfunction in Huntington’s disease

por Martín-Flores, Núria, Pérez-Sisqués, Leticia, Creus-Muncunill, Jordi, Masana, Mercè, Ginés, Sílvia, Alberch, Jordi, Pérez-Navarro, Esther, Malagelada, Cristina
Publicado 2020

Pyk2 Regulates MAMs and Mitochondrial Dynamics in Hippocampal Neurons

por López-Molina, Laura, Fernández-Irigoyen, Joaquín, Cifuentes-Díaz, Carmen, Alberch, Jordi, Girault, Jean-Antoine, Santamaría, Enrique, Ginés, Silvia, Giralt, Albert
Publicado 2022

Pyk2 in the amygdala modulates chronic stress sequelae via PSD-95-related micro-structural changes

por Montalban, Enrica, Al-Massadi, Omar, Sancho-Balsells, Anna, Brito, Verónica, de Pins, Benoit, Alberch, Jordi, Ginés, Silvia, Girault, Jean-Antoine, Giralt, Albert
Publicado 2019

Lack of Helios During Neural Development Induces Adult Schizophrenia-Like Behaviors Associated With Aberrant Levels of the TRIF-Recruiter Protein WDFY1

por Sancho-Balsells, Anna, Brito, Veronica, Fernández, Belissa, Pardo, Mónica, Straccia, Marco, Ginés, Silvia, Alberch, Jordi, Hernández, Isabel, Arranz, Belén, Canals, Josep M., Giralt, Albert
Publicado 2020

Altered m6A RNA methylation contributes to hippocampal memory deficits in Huntington’s disease mice

por Pupak, Anika, Singh, Ankita, Sancho-Balsells, Anna, Alcalá-Vida, Rafael, Espina, Marc, Giralt, Albert, Martí, Eulàlia, Ørom, Ulf Andersson Vang, Ginés, Silvia, Brito, Verónica
Publicado 2022

Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model

por Giralt, Albert, Brito, Veronica, Chevy, Quentin, Simonnet, Clémence, Otsu, Yo, Cifuentes-Díaz, Carmen, de Pins, Benoit, Coura, Renata, Alberch, Jordi, Ginés, Sílvia, Poncer, Jean-Christophe, Girault, Jean-Antoine
Publicado 2017

Placental transfer of NMDAR antibodies causes reversible alterations in mice

por García-Serra, Anna, Radosevic, Marija, Pupak, Anika, Brito, Veronica, Ríos, José, Aguilar, Esther, Maudes, Estibaliz, Ariño, Helena, Spatola, Marianna, Mannara, Francesco, Pedreño, Marta, Joubert, Bastien, Ginés, Silvia, Planagumà, Jesús, Dalmau, Josep
Publicado 2020

Phosphorylation of huntingtin at residue T3 is decreased in Huntington’s disease and modulates mutant huntingtin protein conformation

por Cariulo, Cristina, Azzollini, Lucia, Verani, Margherita, Martufi, Paola, Boggio, Roberto, Chiki, Anass, Deguire, Sean M., Cherubini, Marta, Gines, Silvia, Marsh, J. Lawrence, Conforti, Paola, Cattaneo, Elena, Santimone, Iolanda, Squitieri, Ferdinando, Lashuel, Hilal A., Petricca, Lara, Caricasole, Andrea
Publicado 2017

Modulation of dopamine D(1) receptors via histamine H(3) receptors is a novel therapeutic target for Huntington's disease

por Moreno-Delgado, David, Puigdellívol, Mar, Moreno, Estefanía, Rodríguez-Ruiz, Mar, Botta, Joaquín, Gasperini, Paola, Chiarlone, Anna, Howell, Lesley A, Scarselli, Marco, Casadó, Vicent, Cortés, Antoni, Ferré, Sergi, Guzmán, Manuel, Lluís, Carmen, Alberch, Jordi, Canela, Enric I, Ginés, Silvia, McCormick, Peter J
Publicado 2020

Polyglutamine expansion affects huntingtin conformation in multiple Huntington’s disease models

por Daldin, Manuel, Fodale, Valentina, Cariulo, Cristina, Azzollini, Lucia, Verani, Margherita, Martufi, Paola, Spiezia, Maria Carolina, Deguire, Sean M., Cherubini, Marta, Macdonald, Douglas, Weiss, Andreas, Bresciani, Alberto, Vonsattel, Jean-Paul Gerard, Petricca, Lara, Marsh, J. Lawrence, Gines, Silvia, Santimone, Iolanda, Marano, Massimo, Lashuel, Hilal A., Squitieri, Ferdinando, Caricasole, Andrea
Publicado 2017

Singular Location and Signaling Profile of Adenosine A(2A)-Cannabinoid CB(1) Receptor Heteromers in the Dorsal Striatum

por Moreno, Estefanía, Chiarlone, Anna, Medrano, Mireia, Puigdellívol, Mar, Bibic, Lucka, Howell, Lesley A, Resel, Eva, Puente, Nagore, Casarejos, María J, Perucho, Juan, Botta, Joaquín, Suelves, Nuria, Ciruela, Francisco, Ginés, Silvia, Galve-Roperh, Ismael, Casadó, Vicent, Grandes, Pedro, Lutz, Beat, Monory, Krisztina, Canela, Enric I, Lluís, Carmen, McCormick, Peter J, Guzmán, Manuel
Publicado 2018

Identification of BiP as a CB(1) Receptor-Interacting Protein That Fine-Tunes Cannabinoid Signaling in the Mouse Brain

por Costas-Insua, Carlos, Moreno, Estefanía, Maroto, Irene B., Ruiz-Calvo, Andrea, Bajo-Grañeras, Raquel, Martín-Gutiérrez, David, Diez-Alarcia, Rebeca, Vilaró, M. Teresa, Cortés, Roser, García-Font, Nuria, Martín, Ricardo, Espina, Marc, Botta, Joaquín, Ginés, Silvia, McCormick, Peter J., Sánchez-Prieto, José, Galve-Roperh, Ismael, Mengod, Guadalupe, Urigüen, Leyre, Marsicano, Giovanni, Bellocchio, Luigi, Canela, Enric I., Casadó, Vicent, Rodríguez-Crespo, Ignacio, Guzmán, Manuel
Publicado 2021