Targeting chromosomal sites with locked nucleic acid-modified triplex-forming oligonucleotides: study of efficiency dependence on DNA nuclear environment

por Brunet, Erika, Corgnali, Maddalena, Cannata, Fabio, Perrouault, Loïc, Giovannangeli, Carine
Publicado 2006

High doses of CRISPR/Cas9 ribonucleoprotein efficiently induce gene knockout with low mosaicism in the hydrozoan Clytia hemisphaerica through microhomology-mediated deletion

por Momose, Tsuyoshi, De Cian, Anne, Shiba, Kogiku, Inaba, Kazuo, Giovannangeli, Carine, Concordet, Jean-Paul
Publicado 2018

A hybrid CMV-H1 construct improves efficiency of PEI-delivered shRNA in the mouse brain

por Hassani, Zahra, François, Jean-Christophe, Alfama, Gladys, Dubois, Ghislaine Morvan, Paris, Mathilde, Giovannangeli, Carine, Demeneix, Barbara A.
Publicado 2007

Cellular antisense activity of peptide nucleic acid (PNAs) targeted to HIV-1 polypurine tract (PPT) containing RNA

por Boutimah-Hamoudi, Fatima, Leforestier, Erwan, Sénamaud-Beaufort, Catherine, Nielsen, Peter E., Giovannangeli, Carine, Saison-Behmoaras, Tula Ester
Publicado 2007

Homology-directed Fanconi anemia pathway crosslink repair is dependent on DNA replication

por Nakanishi, Koji, Cavallo, Francesca, Perrouault, Loïc, Giovannangeli, Carine, Moynahan, Mary Ellen, Barchi, Marco, Brunet, Erika, Jasin, Maria
Publicado 2011

The human DNA ends proteome uncovers an unexpected entanglement of functional pathways

por Berthelot, Vivien, Mouta-Cardoso, Gildas, Hégarat, Nadia, Guillonneau, François, François, Jean-Christophe, Giovannangeli, Carine, Praseuth, Danièle, Rusconi, Filippo
Publicado 2016

Sequence-specific DNA cleavage mediated by bipyridine polyamide conjugates

por Simon, Philippe, Cannata, Fabio, Perrouault, Loïc, Halby, Ludovic, Concordet, Jean-Paul, Boutorine, Alexandre, Ryabinin, Vladimir, Sinyakov, Alexandre, Giovannangeli, Carine
Publicado 2008

Chromosomal Translocation Formation Is Sufficient to Produce Fusion Circular RNAs Specific to Patient Tumor Cells

por Babin, Loelia, Piganeau, Marion, Renouf, Benjamin, Lamribet, Khadija, Thirant, Cecile, Deriano, Ludovic, Mercher, Thomas, Giovannangeli, Carine, Brunet, Erika C.
Publicado 2018

Disease modeling by efficient genome editing using a near PAM-less base editor in vivo

por Rosello, Marion, Serafini, Malo, Mignani, Luca, Finazzi, Dario, Giovannangeli, Carine, Mione, Marina C., Concordet, Jean-Paul, Del Bene, Filippo
Publicado 2022

Intercalator conjugates of pyrimidine locked nucleic acid-modified triplex-forming oligonucleotides: improving DNA binding properties and reaching cellular activities

por Brunet, Erika, Corgnali, Maddalena, Perrouault, Loïc, Roig, Victoria, Asseline, Ulysse, Sørensen, Mads D., Babu, B. Ravindra, Wengel, Jesper, Giovannangeli, Carine
Publicado 2005

Stable transmission of targeted gene modification using single-stranded oligonucleotides with flanking LNAs

por Andrieu-Soler, Charlotte, Casas, Mariana, Faussat, Anne-Marie, Gandolphe, Christelle, Doat, Marc, Tempé, Denis, Giovannangeli, Carine, Behar-Cohen, Francine, Concordet, Jean-Paul
Publicado 2005

Molecular basis of the targeting of topoisomerase II-mediated DNA cleavage by VP16 derivatives conjugated to triplex-forming oligonucleotides

por Duca, Maria, Guianvarc'h, Dominique, Oussedik, Kahina, Halby, Ludovic, Garbesi, Anna, Dauzonne, Daniel, Monneret, Claude, Osheroff, Neil, Giovannangeli, Carine, Arimondo, Paola B.
Publicado 2006

Generation of gene-edited rats by delivery of CRISPR/Cas9 protein and donor DNA into intact zygotes using electroporation

por Remy, Séverine, Chenouard, Vanessa, Tesson, Laurent, Usal, Claire, Ménoret, Séverine, Brusselle, Lucas, Heslan, Jean-Marie, Nguyen, Tuan Huan, Bellien, Jeremy, Merot, Jean, De Cian, Anne, Giovannangeli, Carine, Concordet, Jean-Paul, Anegon, Ignacio
Publicado 2017

Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells

por Garcin, Edwige B., Gon, Stéphanie, Sullivan, Meghan R., Brunette, Gregory J., Cian, Anne De, Concordet, Jean-Paul, Giovannangeli, Carine, Dirks, Wilhelm G., Eberth, Sonja, Bernstein, Kara A., Prakash, Rohit, Jasin, Maria, Modesti, Mauro
Publicado 2019

Cancer translocations in human cells induced by zinc finger and TALE nucleases

por Piganeau, Marion, Ghezraoui, Hind, De Cian, Anne, Guittat, Lionel, Tomishima, Mark, Perrouault, Loic, René, Oliver, Katibah, George E., Zhang, Lei, Holmes, Michael C., Doyon, Yannick, Concordet, Jean-Paul, Giovannangeli, Carine, Jasin, Maria, Brunet, Erika
Publicado 2013

Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases

por Remy, Séverine, Tesson, Laurent, Menoret, Séverine, Usal, Claire, De Cian, Anne, Thepenier, Virginie, Thinard, Reynald, Baron, Daniel, Charpentier, Marine, Renaud, Jean-Baptiste, Buelow, Roland, Cost, Gregory J., Giovannangeli, Carine, Fraichard, Alexandre, Concordet, Jean-Paul, Anegon, Ignacio
Publicado 2014

Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins

por Ménoret, Séverine, De Cian, Anne, Tesson, Laurent, Remy, Séverine, Usal, Claire, Boulé, Jean-Baptiste, Boix, Charlotte, Fontanière, Sandra, Crénéguy, Alison, Nguyen, Tuan H., Brusselle, Lucas, Thinard, Reynald, Gauguier, Dominique, Concordet, Jean-Paul, Cherifi, Yacine, Fraichard, Alexandre, Giovannangeli, Carine, Anegon, Ignacio
Publicado 2015

Characterization of Dystrophin Deficient Rats: A New Model for Duchenne Muscular Dystrophy

por Larcher, Thibaut, Lafoux, Aude, Tesson, Laurent, Remy, Séverine, Thepenier, Virginie, François, Virginie, Le Guiner, Caroline, Goubin, Helicia, Dutilleul, Maéva, Guigand, Lydie, Toumaniantz, Gilles, De Cian, Anne, Boix, Charlotte, Renaud, Jean-Baptiste, Cherel, Yan, Giovannangeli, Carine, Concordet, Jean-Paul, Anegon, Ignacio, Huchet, Corinne
Publicado 2014

Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype

por Weber, Leslie, Frati, Giacomo, Felix, Tristan, Hardouin, Giulia, Casini, Antonio, Wollenschlaeger, Clara, Meneghini, Vasco, Masson, Cecile, De Cian, Anne, Chalumeau, Anne, Mavilio, Fulvio, Amendola, Mario, Andre-Schmutz, Isabelle, Cereseto, Anna, El Nemer, Wassim, Concordet, Jean-Paul, Giovannangeli, Carine, Cavazzana, Marina, Miccio, Annarita
Publicado 2020

De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK+ ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells

por Babin, Loélia, Darchen, Alice, Robert, Elie, Aid, Zakia, Borry, Rosalie, Soudais, Claire, Piganeau, Marion, De Cian, Anne, Giovannangeli, Carine, Bawa, Olivia, Rigaud, Charlotte, Scoazec, Jean-Yves, Couronné, Lucile, Veleanu, Layla, Cieslak, Agata, Asnafi, Vahid, Sibon, David, Lamant, Laurence, Meggetto, Fabienne, Mercher, Thomas, Brunet, Erika
Publicado 2022