Tuning Parameters for Polygenic Risk Score Methods Using GWAS Summary Statistics from Training Data

por Jiang, Wei, Chen, Ling, Girgenti, Matthew J., Zhao, Hongyu
Publicado 2023

ZNF804a Regulates Expression of the Schizophrenia-Associated Genes PRSS16, COMT, PDE4B, and DRD2

por Girgenti, Matthew J., LoTurco, Joseph J., Maher, Brady J.
Publicado 2012

Indomethacin induced gene regulation in the rat hippocampus

por Sathyanesan, Monica, Girgenti, Matthew J., Warner-Schmidt, Jennifer, Newton, Samuel S.
Publicado 2015

Transcriptomics of the depressed and PTSD brain

por Zhang, Jing, Kaye, Alfred P., Wang, Jiawei, Girgenti, Matthew J.
Publicado 2021

Prefrontal cortex interneurons display dynamic sex-specific stress-induced transcriptomes

por Girgenti, Matthew J., Wohleb, Eric S., Mehta, Sameet, Ghosal, Sriparna, Fogaca, Manoela V., Duman, Ronald S.
Publicado 2019

InsuLock: A Weakly Supervised Learning Approach for Accurate Insulator Prediction, and Variant Impact Quantification

por Srinivasan, Shushrruth Sai, Gong, Yanwen, Xu, Siwei, Hwang, Ahyeon, Xu, Min, Girgenti, Matthew J., Zhang, Jing
Publicado 2022

Cortical Transcriptomic Alterations in Association With Appetitive Neuropeptides and Body Mass Index in Posttraumatic Stress Disorder

por Stone, Lauren A, Girgenti, Matthew J, Wang, Jiawei, Ji, Dingjue, Zhao, Hongyu, Krystal, John H, Duman, Ronald S
Publicado 2020

Venus: An efficient virus infection detection and fusion site discovery method using single-cell and bulk RNA-seq data

por Lee, Che Yu, Chen, Yuhang, Duan, Ziheng, Xu, Min, Girgenti, Matthew J., Xu, Ke, Gerstein, Mark, Zhang, Jing
Publicado 2022

iHerd: an integrative hierarchical graph representation learning framework to quantify network changes and prioritize risk genes in disease

por Duan, Ziheng, Dai, Yi, Hwang, Ahyeon, Lee, Cheyu, Xie, Kaichi, Xiao, Chutong, Xu, Min, Girgenti, Matthew J., Zhang, Jing
Publicado 2023

Integrating genetics and transcriptomics to study major depressive disorder: a conceptual framework, bioinformatic approaches, and recent findings

por Hicks, Emily M., Seah, Carina, Cote, Alanna, Marchese, Shelby, Brennand, Kristen J., Nestler, Eric J., Girgenti, Matthew J., Huckins, Laura M.
Publicado 2023

Positive modulation of N-methyl-D-aspartate receptors in the mPFC reduces the spontaneous recovery of fear

por Lee, Boyoung, Pothula, Santosh, Wu, Min, Kang, Hyeyeon, Girgenti, Matthew J., Picciotto, Marina R., DiLeone, Ralph J., Taylor, Jane R., Duman, Ronald S.
Publicado 2022

Decoding the role of transcriptomic clocks in the human prefrontal cortex

por Martínez-Magaña, José J., Krystal, John H., Girgenti, Matthew J., Núnez-Ríos, Diana L., Nagamatsu, Sheila T., Andrade-Brito, Diego E., Montalvo-Ortiz, Janitza L.
Publicado 2023

Profiling neuronal methylome and hydroxymethylome of opioid use disorder in the human orbitofrontal cortex

por Rompala, Gregory, Nagamatsu, Sheila T., Martínez-Magaña, José Jaime, Nuñez-Ríos, Diana L., Wang, Jiawei, Girgenti, Matthew J., Krystal, John H., Gelernter, Joel, Hurd, Yasmin L., Montalvo-Ortiz, Janitza L.
Publicado 2023

Epigenome-wide association study of posttraumatic stress disorder identifies novel loci in U.S. military veterans

por Montalvo-Ortiz, Janitza L., Gelernter, Joel, Cheng, Zhongshan, Girgenti, Matthew J., Xu, Ke, Zhang, Xinyu, Gopalan, Shyamalika, Zhou, Hang, Duman, Ronald S., Southwick, Steven M., Krystal, John H., Pietrzak, Robert H.
Publicado 2022

Gene expression in the dorsolateral and ventromedial prefrontal cortices implicates immune-related gene networks in PTSD

por Logue, Mark W., Zhou, Zhenwei, Morrison, Filomene G., Wolf, Erika J., Daskalakis, Nikolaos P., Chatzinakos, Christos, Georgiadis, Foivos, Labadorf, Adam T., Girgenti, Matthew J., Young, Keith A., Williamson, Douglas E., Zhao, Xiang, Grenier, Jaclyn Garza, Huber, Bertrand Russell, Miller, Mark W.
Publicado 2021

Genome-wide association analyses of posttraumatic stress disorder and its symptom subdomains in the Million Veteran Program

por Stein, Murray B., Levey, Daniel F., Cheng, Zhongshan, Wendt, Frank R., Harrington, Kelly, Pathak, Gita A., Cho, Kelly, Quaden, Rachel, Radhakrishnan, Krishnan, Girgenti, Matthew J., Ho, Yuk-Lam Anne, Posner, Daniel, Aslan, Mihaela, Duman, Ronald S., Zhao, Hongyu, Polimanti, Renato, Concato, John, Gelernter, Joel
Publicado 2021

PTSD is associated with neuroimmune suppression: evidence from PET imaging and postmortem transcriptomic studies

por Bhatt, Shivani, Hillmer, Ansel T., Girgenti, Matthew J., Rusowicz, Aleksandra, Kapinos, Michael, Nabulsi, Nabeel, Huang, Yiyun, Matuskey, David, Angarita, Gustavo A., Esterlis, Irina, Davis, Margaret T., Southwick, Steven M., Friedman, Matthew J., Duman, Ronald S., Carson, Richard E., Krystal, John H., Pietrzak, Robert H., Cosgrove, Kelly P.
Publicado 2020

The long noncoding RNA FEDORA is a cell type– and sex-specific regulator of depression

por Issler, Orna, van der Zee, Yentl Y., Ramakrishnan, Aarthi, Xia, Sunhui, Zinsmaier, Alexander K., Tan, Chunfeng, Li, Wei, Browne, Caleb J., Walker, Deena M., Salery, Marine, Torres-Berrío, Angélica, Futamura, Rita, Duffy, Julia E., Labonte, Benoit, Girgenti, Matthew J., Tamminga, Carol A., Dupree, Jeffrey L., Dong, Yan, Murrough, James W., Shen, Li, Nestler, Eric J.
Publicado 2022