Potential RNA-dependent RNA polymerase (RdRp) inhibitors as prospective drug candidates for SARS-CoV-2

por Bekheit, Mohamed S., Panda, Siva S., Girgis, Adel S.
Publicado 2023

Spirooxindole: A Versatile Biologically Active Heterocyclic Scaffold

por Panda, Siva S., Girgis, Adel S., Aziz, Marian N., Bekheit, Mohamed S.
Publicado 2023

Azomethine Ylides—Versatile Synthons for Pyrrolidinyl-Heterocyclic Compounds

por Panda, Siva S., Aziz, Marian N., Stawinski, Jacek, Girgis, Adel S.
Publicado 2023

1′-Methyl-4′-(4-methyl­phen­yl)dispiro­[indane-2,3′-pyrrolidine-2′,3′′-indoline]-1,2′′-dione

por Moustafa, A. M., Girgis, Adel S., Shalaby, S. M., Tiekink, Edward R. T.
Publicado 2012

Synthesis and bio-properties of 4-piperidone containing compounds as curcumin mimics

por Girgis, Adel S., D'Arcy, Padraig, Aboshouk, Dalia R., Bekheit, Mohamed S.
Publicado 2022

Spiroindole-containing compounds bearing phosphonate group of potential M(pro)-SARS-CoV-2 inhibitory properties

por Bekheit, Mohamed S., Panda, Siva S., Kariuki, Benson M., Mahmoud, Sara H., Mostafa, Ahmed, Girgis, Adel S.
Publicado 2023

5-Chloro-5′′-(4-chloro­benzyl­idene)-4′-(4-chloro­phen­yl)-1′,1′′-dimethyldi­spiro­[indoline-3,2′-pyrrolidine-3′,3′′-piperidine]-2,4′′-dione

por Farag, I. S. Ahmed, Girgis, Adel S., Ramadan, A. A., Moustafa, A. M., Mabied, Ahmed F.
Publicado 2014

5′′-Benzyl­idene-5-chloro-1′,1′′-dimethyl-4′-phenyl­dispiro­[indoline-3,2′-pyrrolidine-3′,3′′-piperidine]-2,4′′-dione

por Farag, I. S. Ahmed, Girgis, Adel S., Ramadan, A. A., Moustafa, A. M., Tiekink, Edward R. T.
Publicado 2013

5-Chloro-5′′-(4-chloro­benzyl­idene)-4′-(4-chloro­phen­yl)-1′′-ethyl-1′-methyl­dispiro­[indoline-3,2′-pyrrolidine-3′,3′′-piperidine]-2,4′′-dione

por Farag, I. S. Ahmed, Girgis, Adel S., Ramadan, A. A., Moustafa, A. M., Tiekink, Edward R. T.
Publicado 2013

5-Chloro-5′′-[4-(di­methyl­amino)­benzyl­idene]-4′-[4-(di­methyl­amino)­phen­yl]-1′,1′′-di­methyl­dispiro­[indoline-3,2′-pyrrolidine-3′,3′′-piperidine]-2,4′′-dione...

por Farag, I. S. Ahmed, Girgis, Adel S., Ramadan, A. A., Moustafa, A. M., Tiekink, Edward R. T.
Publicado 2013

Facile synthetic approach towards vasorelaxant active 4-hydroxyquinazoline-4-carboxamides

por Aziz, Marian N., Panda, Siva S., Shalaby, ElSayed M., Fawzy, Nehmedo G., Girgis, Adel S.
Publicado 2019

Indole-Based Compounds as Potential Drug Candidates for SARS-CoV-2

por Girgis, Adel S., Panda, Siva S., Kariuki, Benson M., Bekheit, Mohamed S., Barghash, Reham F., Aboshouk, Dalia R.
Publicado 2023

Synthesis, quantitative structure–property relationship study of novel fluorescence active 2-pyrazolines and application

por Girgis, Adel S., Basta, Altaf H., El-Saied, Houssni, Mohamed, Mohamed A., Bedair, Ahmad H., Salim, Ahmad S.
Publicado 2018

Synthesis, human topoisomerase IIα inhibitory properties and molecular modeling studies of anti-proliferative curcumin mimics

por Fawzy, Nehmedo G., Panda, Siva S., Fayad, Walid, Shalaby, ElSayed M., Srour, Aladdin M., Girgis, Adel S.
Publicado 2019

Protective effects of Aporosa octandra bark extract against D-galactose induced cognitive impairment and oxidative stress in mice

por Panda, Siva S., Girgis, Adel S., Prakash, Atish, Khanna, Leena, Khanna, Pankaj, Shalaby, ElSayed M., Fawzy, Nehmedo G., Jain, Subhash C.
Publicado 2018

Synthesis and molecular modeling studies of cholinesterase inhibitor dispiro[indoline-3,2′-pyrrolidine-3′,3′′-pyrrolidines]

por Youssef, M. Adel, Panda, Siva S., El-Shiekh, Riham A., Shalaby, ElSayed M., Aboshouk, Dalia R., Fayad, Walid, Fawzy, Nehmedo G., Girgis, Adel S.
Publicado 2020

Synthesis, Antibacterial Evaluation, and Computational Studies of a Diverse Set of Linezolid Conjugates

por Bokhtia, Riham M., Girgis, Adel S., Ibrahim, Tarek S., Rasslan, Fatma, Nossier, Eman S., Barghash, Reham F., Sakhuja, Rajeev, Abdel-Aal, Eatedal H., Panda, Siva S., Al-Mahmoudy, Amany M. M.
Publicado 2022

Synthesis, computational studies, antimycobacterial and antibacterial properties of pyrazinoic acid–isoniazid hybrid conjugates

por Panda, Siva S., Girgis, Adel S., Mishra, Bibhuti B., Elagawany, Mohamed, Devarapalli, Venkatasai, Littlefield, William F., Samir, Ahmed, Fayad, Walid, Fawzy, Nehmedo G., Srour, Aladdin M., Bokhtia, Riham M.
Publicado 2019

New NSAID Conjugates as Potent and Selective COX-2 Inhibitors: Synthesis, Molecular Modeling and Biological Investigation

por Bokhtia, Riham M., Panda, Siva S., Girgis, Adel S., Samir, Nermin, Said, Mona F., Abdelnaser, Anwar, Nasr, Soad, Bekheit, Mohamed S., Dawood, Abdelhameed S., Sharma, Horrick, Wade, Margaret, Sharma, Swapnil K., Ghanim, Amany M.
Publicado 2023

Synthesis of aspirin-curcumin mimic conjugates of potential antitumor and anti-SARS-CoV-2 properties

por Srour, Aladdin M., Panda, Siva S., Mostafa, Ahmed, Fayad, Walid, El-Manawaty, May A., A. F. Soliman, Ahmed, Moatasim, Yassmin, El Taweel, Ahmed, Abdelhameed, Mohamed F., Bekheit, Mohamed S., Ali, Mohamed A., Girgis, Adel S.
Publicado 2021