Impact of HLA type, age and chronic viral infection on peripheral T-cell receptor sharing between unrelated individuals

por Johnson, Sarah A., Seale, Spencer L., Gittelman, Rachel M., Rytlewski, Julie A., Robins, Harlan S., Fields, Paul A.
Publicado 2021

Exploring signatures of positive selection in pigmentation candidate genes in populations of East Asian ancestry

por Hider, Jessica L, Gittelman, Rachel M, Shah, Tapan, Edwards, Melissa, Rosenbloom, Arnold, Akey, Joshua M, Parra, Esteban J
Publicado 2013

Comprehensive identification and analysis of human accelerated regulatory DNA

por Gittelman, Rachel M., Hun, Enna, Ay, Ferhat, Madeoy, Jennifer, Pennacchio, Len, Noble, William S., Hawkins, R. David, Akey, Joshua M.
Publicado 2015

A randomised, single-blind, placebo-controlled, dose-finding safety and tolerability study of the anti-CD3 monoclonal antibody otelixizumab in new-onset type 1 diabetes

por Keymeulen, Bart, van Maurik, André, Inman, Dave, Oliveira, João, McLaughlin, Rene, Gittelman, Rachel M., Roep, Bart O., Gillard, Pieter, Hilbrands, Robert, Gorus, Frans, Mathieu, Chantal, Van de Velde, Ursule, Wisniacki, Nicolas, Napolitano, Antonella
Publicado 2020

1165: SARS-COV-2 VACCINATION INDUCES A PREDOMINENTLY CLASS II (CYTOKINE EFFECTOR) T CELL RESPONSE, BUT THE CLASS I RESPONSE IS AUGMENTED BY ANTI-TNF THERAPY AND VACCINE TYPE

por Xu, Alexander, Li, Dalin, Elyanow, Rebecca, Gittelman, Rachel M., Chapman, Heidi, Prostko, John, Pozdnyakova, Valeriya, Debbas, Philip, Mujukian, Angela, Horizon, Arash A., Sobhani, Kimia, Cheng, Susan, Kaplan, Ian M., Mcgovern, Dermot P.B., Merchant, Akil, Melmed, Gil, Braun, Jonathan G.
Publicado 2022

Mo1018: THE T-CELL RESPONSE TO SARS-COV-2 VACCINATION IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE IS OFTEN DEFICIENT IN ANTIBODY-RESPONDERS, AND AUGMENTED BY ANTI-TNF THERAPY

por Li, Dalin, Xu, Alexander, Elyanow, Rebecca, Gittelman, Rachel M., Chapman, Heidi, Prostko, John, Pozdnyakova, Valeriya, Debbas, Philip, Mujukian, Angela, Horizon, Arash A., Sobhani, Kimia, Cheng, Susan, Kaplan, Ian M., Mcgovern, Dermot P.B., Merchant, Akil, Melmed, Gil, Braun, Jonathan G.
Publicado 2022

LB17. Immunosequencing of the T-Cell Receptor Repertoire Reveals Signatures Specific for Diagnosis and Characterization of Early Lyme Disease

por Dalai, Sudeb C, Greissl, Julia, Pesesky, Mitch, Rebman, Allison W, Soloski, Mark J, Horn, Elizabeth J, Dines, Jennifer N, Gittelman, Rachel M, Snyder, Thomas M, Emerson, Ryan O, Meeds, Edward, Manley, Thomas, Kaplan, Ian M, Baldo, Lance, Carlson, Jonathan M, Robins, Harlan S, Aucott, John
Publicado 2021

T-cell receptor sequencing identifies prior SARS-CoV-2 infection and correlates with neutralizing antibody titers and disease severity

por Elyanow, Rebecca, Snyder, Thomas M., Dalai, Sudeb C., Gittelman, Rachel M., Boonyaratanakornkit, Jim, Wald, Anna, Selke, Stacy, Wener, Mark H., Morishima, Chihiro, Greninger, Alex L., Holbrook, Michael R., Kaplan, Ian M., Zahid, H. Jabran, Carlson, Jonathan M., Baldo, Lance, Manley, Thomas, Robins, Harlan S., Koelle, David M.
Publicado 2021

144. Clinical Validation and Performance of a T-cell Immunosequencing Assay to Identify Past SARS-CoV-2 Infection

por Dalai, Sudeb C, Dines, Jennifer N, Snyder, Thomas M, Gittelman, Rachel M, Eerkes, Tera, Vaney, Pashmi, Howard, Sally, Akers, Kipp, Skewis, Lynell, Monteforte, Anthony, Witte, Pamela R, Wolf, Cristina, Nesse, Hans, Qadeer, Jia, Duffy, Sarah, Svejnoha, Emily, Taromino, Caroline, Kagen, Michael, Kaplan, Ian M, Alsobrook, John, Manley, Thomas, Baldo, Lance
Publicado 2021

CD4+ T cell and M2 macrophage infiltration predict dedifferentiated liposarcoma patient outcomes

por Schroeder, Brett A, LaFranzo, Natalie A, LaFleur, Bonnie J, Gittelman, Rachel M, Vignali, Marissa, Zhang, Shihong, Flanagan, Kevin C, Rytlewski, Julie, Riolobos, Laura, Schulte, Brian C, Kim, Teresa S, Chen, Eleanor, Smythe, Kimberly S, Wagner, Michael J, Mantilla, Jose G, Campbell, Jean S, Pierce, Robert H, Jones, Robin L, Cranmer, Lee D, Pollack, Seth M
Publicado 2021

T cell receptor sequencing identifies prior SARS-CoV-2 infection and correlates with neutralizing antibodies and disease severity

por Elyanow, Rebecca, Snyder, Thomas M., Dalai, Sudeb C., Gittelman, Rachel M., Boonyaratanakornkit, Jim, Wald, Anna, Selke, Stacy, Wener, Mark H., Morishima, Chihiro, Greninger, Alexander L., Gale, Michael, Hsiang, Tien-Ying, Jing, Lichen, Holbrook, Michael R., Kaplan, Ian M., Zahid, H. Jabran, May, Damon H., Carlson, Jonathan M., Baldo, Lance, Manley, Thomas, Robins, Harlan S., Koelle, David M.
Publicado 2022

The T-cell clonal response to SARS-CoV-2 vaccination in inflammatory bowel disease patients is augmented by anti-TNF therapy and often deficient in antibody-responders

por Li, Dalin, Xu, Alexander, Mengesha, Emebet, Elyanow, Rebecca, Gittelman, Rachel M., Chapman, Heidi, Prostko, John C., Frias, Edwin C., Stewart, James L., Pozdnyakova, Valeriya, Debbas, Philip, Mujukian, Angela, Horizon, Arash A, Merin, Noah, Joung, Sandy, Botwin, Gregory J., Sobhani, Kimia, Figueiredo, Jane C., Cheng, Susan, Kaplan, Ian M., McGovern, Dermot P.B., Merchant, Akil, Melmed, Gil Y., Braun, Jonathan
Publicado 2021

The T-Cell Response to SARS-CoV-2 Vaccination in Inflammatory Bowel Disease is Augmented with Anti-TNF Therapy

por Li, Dalin, Xu, Alexander, Mengesha, Emebet, Elyanow, Rebecca, Gittelman, Rachel M, Chapman, Heidi, Prostko, John C, Frias, Edwin C, Stewart, James L, Pozdnyakova, Valeriya, Debbas, Philip, Mujukian, Angela, Horizon, Arash A, Merin, Noah, Joung, Sandy, Botwin, Gregory J, Sobhani, Kimia, Figueiredo, Jane C, Cheng, Susan, Kaplan, Ian M, McGovern, Dermot P B, Merchant, Akil, Melmed, Gil Y, Braun, Jonathan
Publicado 2022

A large-scale database of T-cell receptor beta (TCRβ) sequences and binding associations from natural and synthetic exposure to SARS-CoV-2

por Nolan, Sean, Vignali, Marissa, Klinger, Mark, Dines, Jennifer N., Kaplan, Ian M., Svejnoha, Emily, Craft, Tracy, Boland, Katie, Pesesky, Mitch, Gittelman, Rachel M., Snyder, Thomas M., Gooley, Christopher J., Semprini, Simona, Cerchione, Claudio, Mazza, Massimiliano, Delmonte, Ottavia M., Dobbs, Kerry, Carreño-Tarragona, Gonzalo, Barrio, Santiago, Sambri, Vittorio, Martinelli, Giovanni, Goldman, Jason D., Heath, James R., Notarangelo, Luigi D., Carlson, Jonathan M., Martinez-Lopez, Joaquin, Robins, Harlan S.
Publicado 2020

Differences in SARS-CoV-2 Vaccine Response Dynamics Between Class-I- and Class-II-Specific T-Cell Receptors in Inflammatory Bowel Disease

por Xu, Alexander M., Li, Dalin, Ebinger, Joseph E., Mengesha, Emebet, Elyanow, Rebecca, Gittelman, Rachel M., Chapman, Heidi, Joung, Sandy, Botwin, Gregory J., Pozdnyakova, Valeriya, Debbas, Philip, Mujukian, Angela, Prostko, John C., Frias, Edwin C., Stewart, James L., Horizon, Arash A., Merin, Noah, Sobhani, Kimia, Figueiredo, Jane C., Cheng, Susan, Kaplan, Ian M., McGovern, Dermot P. B., Merchant, Akil, Melmed, Gil Y., Braun, Jonathan
Publicado 2022

Longitudinal analysis of T cell receptor repertoires reveals shared patterns of antigen-specific response to SARS-CoV-2 infection

por Gittelman, Rachel M., Lavezzo, Enrico, Snyder, Thomas M., Zahid, H. Jabran, Carty, Cara L., Elyanow, Rebecca, Dalai, Sudeb, Kirsch, Ilan, Baldo, Lance, Manuto, Laura, Franchin, Elisa, Del Vecchio, Claudia, Pacenti, Monia, Boldrin, Caterina, Cattai, Margherita, Saluzzo, Francesca, Padoan, Andrea, Plebani, Mario, Simeoni, Fabio, Bordini, Jessica, Lorè, Nicola I., Lazarević, Dejan, Cirillo, Daniela M., Ghia, Paolo, Toppo, Stefano, Carlson, Jonathan M., Robins, Harlan S., Crisanti, Andrea, Tonon, Giovanni
Publicado 2022

CD8(+) T cell clonotypes from prior SARS-CoV-2 infection predominate during the cellular immune response to mRNA vaccination

por Ford, Emily S., Mayer-Blackwell, Koshlan, Jing, Lichen, Sholukh, Anton M., St. Germain, Russell, Bossard, Emily L., Xie, Hong, Pulliam, Thomas H., Jani, Saumya, Selke, Stacy, Burrow, Carlissa J., McClurkan, Christopher L., Wald, Anna, Holbrook, Michael R., Eaton, Brett, Eudy, Elizabeth, Murphy, Michael, Postnikova, Elena, Robins, Harlan S., Elyanow, Rebecca, Gittelman, Rachel M., Ecsedi, Matyas, Wilcox, Elise, Chapuis, Aude G., Fiore-Gartland, Andrew, Koelle, David M.
Publicado 2022

126. Magnitude and Dynamics of the T-Cell Response to SARS-CoV-2 Infection and Vaccination

por Snyder, Thomas M, Gittelman, Rachel M, Klinger, Mark, May, Damon H, Osborne, Edward J, Taniguchi, Ruth, Jabran Zahid, H, Elyanow, Rebecca, Dalai, Sudeb C, Kaplan, Ian M, Dines, Jennifer N, Noakes, Matthew T, Pandya, Ravi, Baldo, Lance, Semprini, Simona, Cerchione, Claudio, Nicolini, Fabio, Mazza, Massimiliano, Delmonte, Ottavia M, Dobbs, Kerry, Laguna-Goya, Rocio, Carreño-Tarragona, Gonazalo, Barrio, Santiago, Imberti, Luisa, Sottini, Alessandra, Quiros-Roldan, Eugenia, Rossi, Camillo, Biondi, Andrea, Bettini, Laura Rachele, D’Angio, Mariella, Bonfanti, Paolo, Tompkins, Miranda F, Alba, Camille, Dalgard, Clifton, Sambri, Vittorio, Martinelli, Giovanni, Goldman, Jason D, Heath, James R, Su, Helen C, Notarangelo, Luigi D, Paz-Artal, Estela, Martinez-Lopez, Joaquin, Carlson, Jonathan M, Robins, Harlan S
Publicado 2021

Comprehensive T cell repertoire characterization of non-small cell lung cancer

por Reuben, Alexandre, Zhang, Jiexin, Chiou, Shin-Heng, Gittelman, Rachel M., Li, Jun, Lee, Won-Chul, Fujimoto, Junya, Behrens, Carmen, Liu, Xiaoke, Wang, Feng, Quek, Kelly, Wang, Chunlin, Kheradmand, Farrah, Chen, Runzhe, Chow, Chi-Wan, Lin, Heather, Bernatchez, Chantale, Jalali, Ali, Hu, Xin, Wu, Chang-Jiun, Eterovic, Agda Karina, Parra, Edwin Roger, Yusko, Erik, Emerson, Ryan, Benzeno, Sharon, Vignali, Marissa, Wu, Xifeng, Ye, Yuanqing, Little, Latasha D., Gumbs, Curtis, Mao, Xizeng, Song, Xingzhi, Tippen, Samantha, Thornton, Rebecca L., Cascone, Tina, Snyder, Alexandra, Wargo, Jennifer A., Herbst, Roy, Swisher, Stephen, Kadara, Humam, Moran, Cesar, Kalhor, Neda, Zhang, Jianhua, Scheet, Paul, Vaporciyan, Ara A., Sepesi, Boris, Gibbons, Don L., Robins, Harlan, Hwu, Patrick, Heymach, John V., Sharma, Padmanee, Allison, James P., Baladandayuthapani, Veera, Lee, Jack J., Davis, Mark M., Wistuba, Ignacio I., Futreal, P. Andrew, Zhang, Jianjun
Publicado 2020

Magnitude and Dynamics of the T-Cell Response to SARS-CoV-2 Infection at Both Individual and Population Levels

por Snyder, Thomas M., Gittelman, Rachel M., Klinger, Mark, May, Damon H., Osborne, Edward J., Taniguchi, Ruth, Zahid, H. Jabran, Kaplan, Ian M., Dines, Jennifer N., Noakes, Matthew T., Pandya, Ravi, Chen, Xiaoyu, Elasady, Summer, Svejnoha, Emily, Ebert, Peter, Pesesky, Mitchell W., De Almeida, Patricia, O’Donnell, Hope, DeGottardi, Quinn, Keitany, Gladys, Lu, Jennifer, Vong, Allen, Elyanow, Rebecca, Fields, Paul, Greissl, Julia, Baldo, Lance, Semprini, Simona, Cerchione, Claudio, Nicolini, Fabio, Mazza, Massimiliano, Delmonte, Ottavia M., Dobbs, Kerry, Laguna-Goya, Rocio, Carreño-Tarragona, Gonzalo, Barrio, Santiago, Imberti, Luisa, Sottini, Alessandra, Quiros-Roldan, Eugenia, Rossi, Camillo, Biondi, Andrea, Bettini, Laura Rachele, D’Angio, Mariella, Bonfanti, Paolo, Tompkins, Miranda F., Alba, Camille, Dalgard, Clifton, Sambri, Vittorio, Martinelli, Giovanni, Goldman, Jason D., Heath, James R., Su, Helen C., Notarangelo, Luigi D., Paz-Artal, Estela, Martinez-Lopez, Joaquin, Carlson, Jonathan M., Robins, Harlan S.
Publicado 2020