Alpha-to-beta cell trans-differentiation for treatment of diabetes

por Saleh, Mohamed, Gittes, George K., Prasadan, Krishna
Publicado 2021

Intra-amniotic sildenafil treatment improves lung blood flow and pulmonary hypertension in congenital diaphragmatic hernia rats

por Yoshida, Shiho, Kreger, Alexander M., Gittes, George K.
Publicado 2023

High-Affinity Dkk1 Receptor Kremen1 Is Internalized by Clathrin-Mediated Endocytosis

por Mishra, Sanjay K., Funair, Lacey, Cressley, Alex, Gittes, George K., Burns, R. Cartland
Publicado 2012

Time-dependent effects of endogenous hyperglucagonemia on glucose homeostasis and hepatic glucagon action

por Lubaczeuski, Camila, Bozadjieva-Kramer, Nadejda, Louzada, Ruy A., Gittes, George K., Leibowitz, Gil, Bernal-Mizrachi, Ernesto
Publicado 2023

Glucagon Resistance and Decreased Susceptibility to Diabetes in a Model of Chronic Hyperglucagonemia

por Bozadjieva Kramer, Nadejda, Lubaczeuski, Camila, Blandino-Rosano, Manuel, Barker, Grant, Gittes, George K., Caicedo, Alejandro, Bernal-Mizrachi, Ernesto
Publicado 2021

Insulin-positive ductal cells do not migrate into preexisting islets during pregnancy

por Liu, Qun, Jiang, Yinan, Zhu, Lingyan, Qian, Jieqi, Wang, Chaoban, Yang, Tianlun, Prasadan, Krishna, Gittes, George K., Xiao, Xiangwei
Publicado 2021

TGFβ Receptor Signaling Is Essential for Inflammation-Induced but Not β-Cell Workload–Induced β-Cell Proliferation

por Xiao, Xiangwei, Wiersch, John, El-Gohary, Yousef, Guo, Ping, Prasadan, Krishna, Paredes, Jose, Welsh, Carey, Shiota, Chiyo, Gittes, George K.
Publicado 2013

Autophagy protects pancreatic beta cell mass and function in the setting of a high-fat and high-glucose diet

por Sheng, Qingfeng, Xiao, Xiangwei, Prasadan, Krishna, Chen, Congde, Ming, Yungching, Fusco, Joseph, Gangopadhyay, Nupur N., Ricks, David, Gittes, George K.
Publicado 2017

Conversion of α-Cells to β-Cells in the Postpartum Mouse Pancreas Involves Lgr5 Progeny

por Rodriguez, Uylissa A., Socorro, Mairobys, Criscimanna, Angela, Martins, Christina P., Mohamed, Nada, Hu, Jing, Prasadan, Krishna, Gittes, George K., Esni, Farzad
Publicado 2021

β-cell Smad2 null mice have improved β-cell function and are protected from diet-induced hyperglycemia

por Saleh, Mohamed, Mohamed, Nada A., Sehrawat, Anuradha, Zhang, Ting, Thomas, Madison, Wang, Yan, Kalsi, Ranjeet, Molitoris, Justin, Prasadan, Krishna, Gittes, George K.
Publicado 2021

The Expression and Function of Glucose-Dependent Insulinotropic Polypeptide in the Embryonic Mouse Pancreas

por Prasadan, Krishna, Koizumi, Masayuki, Tulachan, Sidhartha, Shiota, Chiyo, Lath, Nikesh, Paredes, Jose, Guo, Ping, El-Gohary, Yousef, Malek, Marcus, Shah, Sohail, Gittes, George K.
Publicado 2011

Focal adhesion kinase-mediated signaling controls the onset of pancreatic cell differentiation

por Rodriguez, Uylissa A., Dahiya, Shakti, Raymond, Michelle L., Gao, Chenxi, Martins-Cargill, Christina P., Piganelli, Jon D., Gittes, George K., Hu, Jing, Esni, Farzad
Publicado 2022

PNA lectin for purifying mouse acinar cells from the inflamed pancreas

por Xiao, Xiangwei, Fischbach, Shane, Fusco, Joseph, Zimmerman, Ray, Song, Zewen, Nebres, Philip, Ricks, David Matthew, Prasadan, Krishna, Shiota, Chiyo, Husain, Sohail Z., Gittes, George K.
Publicado 2016

Identification of Newly Committed Pancreatic Cells in the Adult Mouse Pancreas

por Socorro, Mairobys, Criscimanna, Angela, Riva, Patricia, Tandon, Manuj, Prasadan, Krishna, Guo, Ping, Humar, Abhinav, Husain, Sohail Z., Leach, Steven D., Gittes, George K., Esni, Farzad
Publicado 2017

Placental growth factor in beta cells plays an essential role in gestational beta-cell growth

por Yang, Weixia, Jiang, Yinan, Wang, Yan, Zhang, Ting, Liu, Qun, Wang, Chaoban, Swisher, Grant, Wu, Nannan, Chao, Chelsea, Prasadan, Krishna, Gittes, George K, Xiao, Xiangwei
Publicado 2020

Islet α-cell Inflammation Induced By NF-κB inducing kinase (NIK) Leads to Hypoglycemia, Pancreatitis, Growth Retardation, and Postnatal Death in Mice

por Li, Xinzhi, Jia, Linna, Chen, Xiaoyue, Dong, Ying, Ren, Xiaomeng, Dong, Yuefan, Chen, Ying, Xie, Liwei, Liu, Ming, Shiota, Chiyo, Gittes, George K., Rui, Liangyou, Chen, Zheng
Publicado 2018

Cellular Autophagy in α Cells Plays a Role in the Maintenance of Islet Architecture

por Himuro, Miwa, Miyatsuka, Takeshi, Suzuki, Luka, Miura, Masaki, Katahira, Takehiro, Goto, Hiromasa, Nishida, Yuya, Sasaki, Shugo, Koike, Masato, Shiota, Chiyo, Gittes, George K, Fujitani, Yoshio, Watada, Hirotaka
Publicado 2019

Bone-marrow derived cells do not contribute to new beta-cells in the inflamed pancreas

por Jiang, Yinan, Wiersch, John, Wu, Wei, Qian, Jieqi, Adama, Maharana Prathap R., Wu, Nannan, Yang, Weixia, Chen, Congde, Zhu, Lingyan, Prasadan, Krishna, Gittes, George K., Xiao, Xiangwei
Publicado 2023

Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer

por Melamed, Jilian R., Yerneni, Saigopalakrishna S., Arral, Mariah L., LoPresti, Samuel T., Chaudhary, Namit, Sehrawat, Anuradha, Muramatsu, Hiromi, Alameh, Mohamad-Gabriel, Pardi, Norbert, Weissman, Drew, Gittes, George K., Whitehead, Kathryn A.
Publicado 2023

Targeted Inhibition of Pancreatic Acinar Cell Calcineurin Is a Novel Strategy to Prevent Post-ERCP Pancreatitis

por Orabi, Abrahim I., Wen, Li, Javed, Tanveer A., Le, Tianming, Guo, Ping, Sanker, Subramaniam, Ricks, David, Boggs, Kristy, Eisses, John F., Castro, Carlos, Xiao, Xiangwei, Prasadan, Krishna, Esni, Farzad, Gittes, George K., Husain, Sohail Z.
Publicado 2016