In Silico Insights towards the Identification of SARS-CoV-2 NSP13 Helicase Druggable Pockets

por Ricci, Federico, Gitto, Rosaria, Pitasi, Giovanna, De Luca, Laura
Publicado 2022

In Silico Strategy for Targeting the mTOR Kinase at Rapamycin Binding Site by Small Molecules

por Vittorio, Serena, Gitto, Rosaria, Adornato, Ilenia, Russo, Emilio, De Luca, Laura
Publicado 2021

Exploring Molecular Contacts of MUC1 at CIN85 Binding Interface to Address Future Drug Design Efforts

por Gulotta, Maria Rita, Vittorio, Serena, Gitto, Rosaria, Perricone, Ugo, De Luca, Laura
Publicado 2021

In Silico Identification of Potential Druggable Binding Sites on CIN85 SH3 Domain

por Vittorio, Serena, Seidel, Thomas, Garon, Arthur, Gitto, Rosaria, Langer, Thierry, De Luca, Laura
Publicado 2021

Rational design of small molecules able to inhibit α-synuclein amyloid aggregation for the treatment of Parkinson’s disease

por Vittorio, Serena, Adornato, Ilenia, Gitto, Rosaria, Peña-Díaz, Samuel, Ventura, Salvador, De Luca, Laura
Publicado 2020

Seeking new approach for therapeutic treatment of cholera disease via inhibition of bacterial carbonic anhydrases: experimental and theoretical studies for sixteen benzenesulfonami...

por Gitto, Rosaria, De Luca, Laura, Mancuso, Francesca, Del Prete, Sonia, Vullo, Daniela, Supuran, Claudiu T., Capasso, Clemente
Publicado 2019

Synthesis, computational studies and assessment of in vitro inhibitory activity of umbelliferon-based compounds against tumour-associated carbonic anhydrase isoforms IX and XII

por Mancuso, Francesca, De Luca, Laura, Angeli, Andrea, Del Prete, Sonia, Capasso, Clemente, Supuran, Claudiu T., Gitto, Rosaria
Publicado 2020

Evaluation of the In Vitro Antifungal Activity of Novel Arylsulfonamides against Candida spp.

por Ginestra, Giovanna, Gervasi, Teresa, Mancuso, Francesca, Bucolo, Federica, De Luca, Laura, Gitto, Rosaria, Barreca, Davide, Mandalari, Giuseppina
Publicado 2023

Discovery and computational studies of piperidine/piperazine-based compounds endowed with sigma receptor affinity

por De Luca, Laura, Lombardo, Lisa, Mirabile, Salvatore, Marrazzo, Agostino, Dichiara, Maria, Cosentino, Giuseppe, Amata, Emanuele, Gitto, Rosaria
Publicado 2023

Microwave Assisted Organic Synthesis (MAOS) of Small Molecules as Potential HIV-1 Integrase Inhibitors

por Ferro, Stefania, Grazia, Sara De, Luca, Laura De, Gitto, Rosaria, Faliti, Caterina Elisa, Debyzer, Zeger, Chimirri, Alba
Publicado 2011

4‐Sulfamoylphenylalkylamides as Inhibitors of Carbonic Anhydrases Expressed in Vibrio cholerae

por Mancuso, Francesca, De Luca, Laura, Bucolo, Federica, Vrabel, Milan, Angeli, Andrea, Capasso, Clemente, Supuran, Claudiu T., Gitto, Rosaria
Publicado 2021

Leveraging the 3-Chloro-4-fluorophenyl Motif to Identify Inhibitors of Tyrosinase from Agaricus bisporus

por Mirabile, Salvatore, Ielo, Laura, Lombardo, Lisa, Ricci, Federico, Gitto, Rosaria, Germanò, Maria Paola, Pace, Vittorio, De Luca, Laura
Publicado 2023

Ligand-Based Discovery of a Small Molecule as Inhibitor of α-Synuclein Amyloid Formation

por De Luca, Laura, Vittorio, Serena, Peña-Díaz, Samuel, Pitasi, Giovanna, Fornt-Suñé, Marc, Bucolo, Federica, Ventura, Salvador, Gitto, Rosaria
Publicado 2022

The SIRT2 Pathway Is Involved in the Antiproliferative Effect of Flavanones in Human Leukemia Monocytic THP-1 Cells

por Russo, Caterina, Maugeri, Alessandro, De Luca, Laura, Gitto, Rosaria, Lombardo, Giovanni Enrico, Musumeci, Laura, De Sarro, Giovambattista, Cirmi, Santa, Navarra, Michele
Publicado 2022

Discovery of Neuroprotective Agents Based on a 5-(4-Pyridinyl)-1,2,4-triazole Scaffold

por Gitto, Rosaria, Vittorio, Serena, Bucolo, Federica, Peña-Díaz, Samuel, Siracusa, Rosalba, Cuzzocrea, Salvatore, Ventura, Salvador, Di Paola, Rosanna, De Luca, Laura
Publicado 2022

Evaluation of 4‐(4‐Fluorobenzyl)piperazin‐1‐yl]‐Based Compounds as Competitive Tyrosinase Inhibitors Endowed with Antimelanogenic Effects

por Mirabile, Salvatore, Vittorio, Serena, Paola Germanò, Maria, Adornato, Ilenia, Ielo, Laura, Rapisarda, Antonio, Gitto, Rosaria, Pintus, Francesca, Fais, Antonella, De Luca, Laura
Publicado 2021

Design, Synthesis, and in Vitro Evaluation of 4‐(4‐Hydroxyphenyl)piperazine‐Based Compounds Targeting Tyrosinase

por Mirabile, Salvatore, Germanò, Maria Paola, Fais, Antonella, Lombardo, Lisa, Ricci, Federico, Floris, Sonia, Cacciola, Anna, Rapisarda, Antonio, Gitto, Rosaria, De Luca, Laura
Publicado 2022

Structure-based design of a phosphotyrosine-masked covalent ligand targeting the E3 ligase SOCS2

por Ramachandran, Sarath, Makukhin, Nikolai, Haubrich, Kevin, Nagala, Manjula, Forrester, Beth, Lynch, Dylan M., Casement, Ryan, Testa, Andrea, Bruno, Elvira, Gitto, Rosaria, Ciulli, Alessio
Publicado 2023