IFNα Impairs Autophagic Degradation of mtDNA Promoting Autoreactivity of SLE Monocytes in a STING-Dependent Fashion

por Gkirtzimanaki, Katerina, Kabrani, Eleni, Nikoleri, Dimitra, Polyzos, Alexander, Blanas, Athanasios, Sidiropoulos, Prodromos, Makrigiannakis, Antonis, Bertsias, George, Boumpas, Dimitrios T., Verginis, Panayotis
Publicado 2018

R-loops trigger the release of cytoplasmic ssDNAs leading to chronic inflammation upon DNA damage

por Chatzidoukaki, Ourania, Stratigi, Kalliopi, Goulielmaki, Evi, Niotis, George, Akalestou-Clocher, Alexia, Gkirtzimanaki, Katerina, Zafeiropoulos, Alexandros, Altmüller, Janine, Topalis, Pantelis, Garinis, George A.
Publicado 2021

Tissue-infiltrating macrophages mediate an exosome-based metabolic reprogramming upon DNA damage

por Goulielmaki, Evi, Ioannidou, Anna, Tsekrekou, Maria, Stratigi, Kalliopi, Poutakidou, Ioanna K., Gkirtzimanaki, Katerina, Aivaliotis, Michalis, Evangelou, Konstantinos, Topalis, Pantelis, Altmüller, Janine, Gorgoulis, Vassilis G., Chatzinikolaou, Georgia, Garinis, George A.
Publicado 2020

NETs decorated with bioactive IL-33 infiltrate inflamed tissues and induce IFN-α production in patients with SLE

por Georgakis, Spiros, Gkirtzimanaki, Katerina, Papadaki, Garyfalia, Gakiopoulou, Hariklia, Drakos, Elias, Eloranta, Maija-Leena, Makridakis, Manousos, Kontostathi, Georgia, Zoidakis, Jerome, Baira, Eirini, Rönnblom, Lars, Boumpas, Dimitrios T., Sidiropoulos, Prodromos, Verginis, Panayotis, Bertsias, George
Publicado 2021