Enhanced clinical-scale manufacturing of TCR transduced T-cells using closed culture system modules

por Jin, Jianjian, Gkitsas, Nikolaos, Fellowes, Vicki S., Ren, Jiaqiang, Feldman, Steven A., Hinrichs, Christian S., Stroncek, David F., Highfill, Steven L.
Publicado 2018

Cancer targeting by TCR gene-engineered T cells directed against Kita-Kyushu Lung Cancer Antigen-1

por Marcinkowski, Bridget, Stevanović, Sanja, Helman, Sarah R., Norberg, Scott M., Serna, Carylinda, Jin, Benjamin, Gkitsas, Nikolaos, Kadakia, Tejas, Warner, Andrew, Davis, Jeremy L., Rooper, Lisa, Hinrichs, Christian S.
Publicado 2019

Application of droplet digital PCR for the detection of vector copy number in clinical CAR/TCR T cell products

por Lu, Alex, Liu, Hui, Shi, Rongye, Cai, Yihua, Ma, Jinxia, Shao, Lipei, Rong, Victor, Gkitsas, Nikolaos, Lei, Hong, Highfill, Steven L., Panch, Sandhya, Stroncek, David F., Jin, Ping
Publicado 2020

Establishment and validation of in-house cryopreserved CAR/TCR-T cell flow cytometry quality control

por Cai, Yihua, Prochazkova, Michaela, Jiang, Chunjie, Song, Hannah W., Jin, Jianjian, Moses, Larry, Gkitsas, Nikolaos, Somerville, Robert P., Highfill, Steven L., Panch, Sandhya, Stroncek, David F., Jin, Ping
Publicado 2021

Homology-independent targeted insertion (HITI) enables guided CAR knock-in and efficient clinical scale CAR-T cell manufacturing

por Balke-Want, Hyatt, Keerthi, Vimal, Gkitsas, Nikolaos, Mancini, Andrew G., Kurgan, Gavin L., Fowler, Carley, Xu, Peng, Liu, Xikun, Asano, Kyle, Patel, Sunny, Fisher, Christopher J., Brown, Annie K., Tunuguntla, Ramya H., Patel, Shabnum, Sotillo, Elena, Mackall, Crystal L., Feldman, Steven A.
Publicado 2023

Inosine Induces Stemness Features in CAR T cells and Enhances Potency

por Klysz, Dorota D., Fowler, Carley, Malipatlolla, Meena, Stuani, Lucille, Freitas, Katherine A., Meier, Stefanie, Daniel, Bence, Sandor, Katalin, Xu, Peng, Huang, Jing, Labanieh, Louai, Leruste, Amaury, Bashti, Malek, Keerthi, Vimal, Mata-Alcazar, Janette, Gkitsas, Nikolaos, Guerrero, Justin A., Fisher, Chris, Patel, Sunny, Asano, Kyle, Patel, Shabnum, Davis, Kara L., Satpathy, Ansuman T., Feldman, Steven A., Sotillo, Elena, Mackall, Crystal L.
Publicado 2023

CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trial

por Spiegel, Jay Y., Patel, Shabnum, Muffly, Lori, Hossain, Nasheed M., Oak, Jean, Baird, John H., Frank, Matthew J., Shiraz, Parveen, Sahaf, Bita, Craig, Juliana, Iglesias, Maria, Younes, Sheren, Natkunam, Yasodha, Ozawa, Michael G., Yang, Eric, Tamaresis, John, Chinnasamy, Harshini, Ehlinger, Zach, Reynolds, Warren, Lynn, Rachel, Rotiroti, Maria Caterina, Gkitsas, Nikolaos, Arai, Sally, Johnston, Laura, Lowsky, Robert, Majzner, Robbie G., Meyer, Everett, Negrin, Robert S., Rezvani, Andrew R., Sidana, Surbhi, Shizuru, Judith, Weng, Wen-Kai, Mullins, Chelsea, Jacob, Allison, Kirsch, Ilan, Bazzano, Magali, Zhou, Jing, Mackay, Sean, Bornheimer, Scott J., Schultz, Liora, Ramakrishna, Sneha, Davis, Kara L., Kong, Katherine A., Shah, Nirali N., Qin, Haiying, Fry, Terry, Feldman, Steven, Mackall, Crystal L., Miklos, David B.
Publicado 2021