Epitomic Characterization of the Specificity of the Anti-Amyloid Aβ Monoclonal Antibodies 6E10 and 4G8

por Baghallab, Ibtisam, Reyes-Ruiz, Jorge Mauricio, Abulnaja, Khalid, Huwait, Etimad, Glabe, Charles
Publicado 2018

Intracellular Injection of Brain Extracts from Alzheimer’s Disease Patients Triggers Unregulated Ca(2+) Release from Intracellular Stores That Hinders Cellular Bioenergetics

por Pensalfini, Anna, Umar, Abdul Rahim, Glabe, Charles, Parker, Ian, Ullah, Ghanim, Demuro, Angelo
Publicado 2022

Age-Related Oxidative Redox and Metabolic Changes Precede Intraneuronal Amyloid-β Accumulation and Plaque Deposition in a Transgenic Alzheimer’s Disease Mouse Model

por Pontrello, Crystal G., McWhirt, Joshua M., Glabe, Charles G., Brewer, Gregory J.
Publicado 2022

Soluble Amyloid Oligomers Increase Bilayer Conductance by Altering Dielectric Structure

por Sokolov, Yuri, Kozak, J. Ashot, Kayed, Rakez, Chanturiya, Alexandr, Glabe, Charles, Hall, James E.
Publicado 2006

Título no disponible

por Sokolov, Yuri, Kozak, J. Ashot, Kayed, Rakez, Chanturiya, Alexandr, Glabe, Charles, Hall, James E.
Publicado 2006

Tau-dependent microtubule disassembly initiated by prefibrillar β-amyloid

por King, Michelle E., Kan, Ho-Man, Baas, Peter W., Erisir, Alev, Glabe, Charles G., Bloom, George S.
Publicado 2006

Amyloid Beta Annular Protofibrils in Cell Processes and Synapses Accumulate with Aging and Alzheimer-Associated Genetic Modification

por Kokubo, Hideko, Kayed, Rakez, Glabe, Charles G., Staufenbiel, Matthias, Saido, Takaomi C., Iwata, Nobuhisa, Yamaguchi, Haruyasu
Publicado 2009

Conformation-Dependent Oligomers in Cerebrospinal Fluid of Presymptomatic Familial Alzheimer's Disease Mutation Carriers

por Ringman, John M., Tomic, Jennifer L., Coppola, Giovanni, Elashoff, David, Gylys, Karen H., Glabe, Charles G.
Publicado 2012

Age-Related Intraneuronal Aggregation of Amyloid-β in Endosomes, Mitochondria, Autophagosomes, and Lysosomes

por Brewer, Gregory J., Herrera, Robert A., Philipp, Stephan, Sosna, Justyna, Reyes-Ruiz, Jorge Mauricio, Glabe, Charles G.
Publicado 2020

Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid

por Nichol, Kathryn E, Poon, Wayne W, Parachikova, Anna I, Cribbs, David H, Glabe, Charles G, Cotman, Carl W
Publicado 2008

Formation of soluble amyloid oligomers and amyloid fibrils by the multifunctional protein vitronectin

por Shin, Thuzar M, Isas, J Mario, Hsieh, Chia-Ling, Kayed, Rakez, Glabe, Charles G, Langen, Ralf, Chen, Jeannie
Publicado 2008

Protective Effect of Geranylgeranylacetone via Enhancement of HSPB8 Induction in Desmin-Related Cardiomyopathy

por Sanbe, Atsushi, Daicho, Takuya, Mizutani, Reiko, Endo, Toshiya, Miyauchi, Noriko, Yamauchi, Junji, Tanonaka, Kouichi, Glabe, Charles, Tanoue, Akito
Publicado 2009

Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar olig...

por Sosna, Justyna, Philipp, Stephan, Albay, Ricardo, Reyes-Ruiz, Jorge Mauricio, Baglietto-Vargas, David, LaFerla, Frank M., Glabe, Charles G.
Publicado 2018

Novel Aβ peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease

por Zhou, Jun, Fonseca, Maria I, Kayed, Rakez, Hernandez, Irma, Webster, Scott D, Yazan, Ozkan, Cribbs, David H, Glabe, Charles G, Tenner, Andrea J
Publicado 2005

An “epitomic” analysis of the specificity of conformation-dependent, anti-Aß amyloid monoclonal antibodies

por Reyes-Ruiz, Jorge Mauricio, Nakajima, Rie, Baghallab, Ibtisam, Goldschmidt, Luki, Sosna, Justyna, Mai Ho, Phuong Nguyen, Kumosani, Taha, Felgner, Philip L., Glabe, Charles
Publicado 2020

Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers

por Kayed, Rakez, Canto, Isabel, Breydo, Leonid, Rasool, Suhail, Lukacsovich , Tamas, Wu, Jessica, Albay, Ricardo, Pensalfini, Anna, Yeung, Stephen, Head, Elizabeth, Marsh, J Lawrence, Glabe, Charles
Publicado 2010

Vaccination with a non-human random sequence amyloid oligomer mimic results in improved cognitive function and reduced plaque deposition and micro hemorrhage in Tg2576 mice

por Rasool, Suhail, Albay, Ricardo, Martinez-Coria, Hilda, Breydo, Leonid, Wu, Jessica, Milton, Saskia, Misra, Sunit, Tran, Andy, Pensalfini, Anna, Laferla, Frank, Kayed, Rakez, Glabe, Charles G
Publicado 2012

CNI-1493 inhibits Aβ production, plaque formation, and cognitive deterioration in an animal model of Alzheimer's disease

por Bacher, Michael, Dodel, Richard, Aljabari, Bayan, Keyvani, Kathy, Marambaud, Philippe, Kayed, Rakez, Glabe, Charles, Goertz, Nicole, Hoppmann, Anne, Sachser, Norbert, Klotsche, Jens, Schnell, Susanne, Lewejohann, Lars, Al-Abed, Yousef
Publicado 2008

Effect of Synthetic Aβ Peptide Oligomers and Fluorinated Solvents on Kv1.3 Channel Properties and Membrane Conductance

por Lioudyno, Maria I., Broccio, Matteo, Sokolov, Yuri, Rasool, Suhail, Wu, Jessica, Alkire, Michael T., Liu, Virginia, Kozak, J. Ashot, Dennison, Philip R., Glabe, Charles G., Lösche, Mathias, Hall, James E.
Publicado 2012

Unexpected partial correction of metabolic and behavioral phenotypes of Alzheimer’s APP/PSEN1 mice by gene targeting of diabetes/Alzheimer’s-related Sorcs1

por Knight, Elysse M., Ruiz, Henry H., Kim, Soong Ho, Harte, Jessica C., Hsieh, Wilson, Glabe, Charles, Klein, William L., Attie, Alan D., Buettner, Christoph, Ehrlich, Michelle E., Gandy, Sam
Publicado 2016