Transcriptional and Non-Transcriptional Activation, Posttranslational Modifications, and Antiviral Functions of Interferon Regulatory Factor 3 and Viral Antagonism by the SARS-Coro...

por Glanz, Anna, Chakravarty, Sukanya, Varghese, Merina, Kottapalli, Anita, Fan, Shumin, Chakravarti, Ritu, Chattopadhyay, Saurabh
Publicado 2021

Autophagic degradation of IRF3 induced by the small-molecule auranofin inhibits its transcriptional and proapoptotic activities

por Glanz, Anna, Chakravarty, Sukanya, Fan, Shumin, Chawla, Karan, Subramanian, Gayatri, Rahman, Tia, Walters, Dean, Chakravarti, Ritu, Chattopadhyay, Saurabh
Publicado 2021

IRF3 inhibits nuclear translocation of NF-κB to prevent viral inflammation

por Popli, Sonam, Chakravarty, Sukanya, Fan, Shumin, Glanz, Anna, Aras, Siddhesh, Nagy, Laura E., Sen, Ganes C., Chakravarti, Ritu, Chattopadhyay, Saurabh
Publicado 2022

High Throughput Screening of FDA-Approved Drug Library Reveals the Compounds that Promote IRF3-Mediated Pro-Apoptotic Pathway Inhibit Virus Replication

por Glanz, Anna, Chawla, Karan, Fabry, Stephanie, Subramanian, Gayatri, Garcia, Julie, Jay, Bryanna, Ciricillo, Jacob, Chakravarti, Ritu, Taylor, R. Travis, Chattopadhyay, Saurabh
Publicado 2020