Fasting and time of day independently modulate circadian rhythm relevant gene expression in adipose and skin tissue

por Couto Alves, Alexessander, Glastonbury, Craig A., El-Sayed Moustafa, Julia S., Small, Kerrin S.
Publicado 2018

Cell-Type Heterogeneity in Adipose Tissue Is Associated with Complex Traits and Reveals Disease-Relevant Cell-Specific eQTLs

por Glastonbury, Craig A., Couto Alves, Alexessander, El-Sayed Moustafa, Julia S., Small, Kerrin S.
Publicado 2019

Metabolomic profiling to dissect the role of visceral fat in cardiometabolic health

por Menni, Cristina, Migaud, Marie, Glastonbury, Craig A., Beaumont, Michelle, Nikolaou, Aikaterini, Small, Kerrin S., Brosnan, Mary Julia, Mohney, Robert P., Spector, Tim D., Valdes, Ana M.
Publicado 2016

Adiposity-Dependent Regulatory Effects on Multi-tissue Transcriptomes

por Glastonbury, Craig A., Viñuela, Ana, Buil, Alfonso, Halldorsson, Gisli H., Thorleifsson, Gudmar, Helgason, Hannes, Thorsteinsdottir, Unnur, Stefansson, Kari, Dermitzakis, Emmanouil T., Spector, Tim D., Small, Kerrin S.
Publicado 2016

An automatic entropy method to efficiently mask histology whole-slide images

por Song, Yipei, Cisternino, Francesco, Mekke, Joost M., de Borst, Gert J., de Kleijn, Dominique P. V., Pasterkamp, Gerard, Vink, Aryan, Glastonbury, Craig A., van der Laan, Sander W., Miller, Clint L.
Publicado 2023

Machine Learning based histology phenotyping to investigate the epidemiologic and genetic basis of adipocyte morphology and cardiometabolic traits

por Glastonbury, Craig A., Pulit, Sara L., Honecker, Julius, Censin, Jenny C., Laber, Samantha, Yaghootkar, Hanieh, Rahmioglu, Nilufer, Pastel, Emilie, Kos, Katerina, Pitt, Andrew, Hudson, Michelle, Nellåker, Christoffer, Beer, Nicola L., Hauner, Hans, Becker, Christian M., Zondervan, Krina T., Frayling, Timothy M., Claussnitzer, Melina, Lindgren, Cecilia M.
Publicado 2020

Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS

por Pan, David Z., Garske, Kristina M., Alvarez, Marcus, Bhagat, Yash V., Boocock, James, Nikkola, Elina, Miao, Zong, Raulerson, Chelsea K., Cantor, Rita M., Civelek, Mete, Glastonbury, Craig A., Small, Kerrin S., Boehnke, Michael, Lusis, Aldons J., Sinsheimer, Janet S., Mohlke, Karen L., Laakso, Markku, Pajukanta, Päivi, Ko, Arthur
Publicado 2018

Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS

por Pan, David Z., Garske, Kristina M., Alvarez, Marcus, Bhagat, Yash V., Boocock, James, Nikkola, Elina, Miao, Zong, Raulerson, Chelsea K., Cantor, Rita M., Civelek, Mete, Glastonbury, Craig A., Small, Kerrin S., Boehnke, Michael, Lusis, Aldons J., Sinsheimer, Janet S., Mohlke, Karen L., Laakso, Markku, Pajukanta, Päivi, Ko, Arthur
Publicado 2018

Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health

por Tsai, Pei-Chien, Glastonbury, Craig A., Eliot, Melissa N., Bollepalli, Sailalitha, Yet, Idil, Castillo-Fernandez, Juan E., Carnero-Montoro, Elena, Hardiman, Thomas, Martin, Tiphaine C., Vickers, Alice, Mangino, Massimo, Ward, Kirsten, Pietiläinen, Kirsi H., Deloukas, Panos, Spector, Tim D., Viñuela, Ana, Loucks, Eric B., Ollikainen, Miina, Kelsey, Karl T., Small, Kerrin S., Bell, Jordana T.
Publicado 2018

GWAS Identifies Risk Locus for Erectile Dysfunction and Implicates Hypothalamic Neurobiology and Diabetes in Etiology

por Bovijn, Jonas, Jackson, Leigh, Censin, Jenny, Chen, Chia-Yen, Laisk, Triin, Laber, Samantha, Ferreira, Teresa, Pulit, Sara L., Glastonbury, Craig A., Smoller, Jordan W., Harrison, Jamie W., Ruth, Katherine S., Beaumont, Robin N., Jones, Samuel E., Tyrrell, Jessica, Wood, Andrew R., Weedon, Michael N., Mägi, Reedik, Neale, Benjamin, Lindgren, Cecilia M., Murray, Anna, Holmes, Michael V.
Publicado 2019

Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry

por Pulit, Sara L, Stoneman, Charli, Morris, Andrew P, Wood, Andrew R, Glastonbury, Craig A, Tyrrell, Jessica, Yengo, Loïc, Ferreira, Teresa, Marouli, Eirini, Ji, Yingjie, Yang, Jian, Jones, Samuel, Beaumont, Robin, Croteau-Chonka, Damien C, Winkler, Thomas W, Hattersley, Andrew T, Loos, Ruth J F, Hirschhorn, Joel N, Visscher, Peter M, Frayling, Timothy M, Yaghootkar, Hanieh, Lindgren, Cecilia M
Publicado 2019

Further evidence supporting a potential role for ADH1B in obesity

por Morales, Liza D., Cromack, Douglas T., Tripathy, Devjit, Fourcaudot, Marcel, Kumar, Satish, Curran, Joanne E., Carless, Melanie, Göring, Harald H. H., Hu, Shirley L., Lopez-Alvarenga, Juan Carlos, Garske, Kristina M., Pajukanta, Päivi, Small, Kerrin S., Glastonbury, Craig A., Das, Swapan K., Langefeld, Carl, Hanson, Robert L., Hsueh, Wen-Chi, Norton, Luke, Arya, Rector, Mummidi, Srinivas, Blangero, John, DeFronzo, Ralph A., Duggirala, Ravindranath, Jenkinson, Christopher P.
Publicado 2021

Identification of Rare Loss-of-Function Genetic Variation Regulating Body Fat Distribution

por Koprulu, Mine, Zhao, Yajie, Wheeler, Eleanor, Dong, Liang, Rocha, Nuno, Li, Chen, Griffin, John D, Patel, Satish, Van de Streek, Marcel, Glastonbury, Craig A, Stewart, Isobel D, Day, Felix R, Luan, Jian’an, Bowker, Nicholas, Wittemans, Laura B L, Kerrison, Nicola D, Cai, Lina, Lucarelli, Debora M E, Barroso, Inês, McCarthy, Mark I, Scott, Robert A, Saudek, Vladimir, Small, Kerrin S, Wareham, Nicholas J, Semple, Robert K, Perry, John R B, O’Rahilly, Stephen, Lotta, Luca A, Langenberg, Claudia, Savage, David B
Publicado 2021

Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition

por Small, Kerrin S., Todorčević, Marijana, Civelek, Mete, El-Sayed Moustafa, Julia S., Wang, Xiao, Simon, Michelle M., Fernandez-Tajes, Juan, Mahajan, Anubha, Horikoshi, Momoko, Hugill, Alison, Glastonbury, Craig A., Quaye, Lydia, Neville, Matt J., Sethi, Siddharth, Yon, Marianne, Pan, Calvin, Che, Nam, Viñuela, Ana, Tsai, Pei-Chien, Nag, Abhishek, Buil, Alfonso, Thorleifsson, Gudmar, Raghavan, Avanthi, Ding, Qiurong, Morris, Andrew P., Bell, Jordana T., Thorsteinsdottir, Unnur, Stefansson, Kari, Laakso, Markku, Dahlman, Ingrid, Arner, Peter, Gloyn, Anna L., Musunuru, Kiran, Lusis, Aldons J., Cox, Roger, Karpe, Fredrik, McCarthy, Mark I.
Publicado 2018

Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open angle glaucoma

por Cooke Bailey, Jessica N., Loomis, Stephanie J., Kang, Jae H., Allingham, R. Rand, Gharahkhani, Puya, Khor, Chiea Chuen, Burdon, Kathryn P., Aschard, Hugues, Chasman, Daniel I., Igo, Robert P., Hysi, Pirro G., Glastonbury, Craig A., Ashley-Koch, Allison, Brilliant, Murray, Brown, Andrew A., Budenz, Donald L., Buil, Alfonso, Cheng, Ching-Yu, Choi, Hyon, Christen, William G., Curhan, Gary, De Vivo, Immaculata, Fingert, John H., Foster, Paul J., Fuchs, Charles, Gaasterland, Douglas, Gaasterland, Terry, Hewitt, Alex W., Hu, Frank, Hunter, David J., Khawaja, Anthony P., Lee, Richard K., Li, Zheng, Lichter, Paul R., Mackey, David A., McGuffin, Peter, Mitchell, Paul, Moroi, Sayoko E., Perera, Shamira A., Pepper, Keating W., Qi, Qibin, Realini, Tony, Richards, Julia E., Ridker, Paul M, Rimm, Eric, Ritch, Robert, Ritchie, Marylyn, Schuman, Joel S., Scott, William K., Singh, Kuldev, Sit, Arthur J., Song, Yeunjoo E., Tamimi, Rulla M., Topouzis, Fotis, Viswanathan, Ananth C., Verma, Shefali Setia, Vollrath, Douglas, Wang, Jie Jin, Weisschuh, Nicole, Wissinger, Bernd, Wollstein, Gadi, Wong, Tien Y., Yaspan, Brian L., Zack, Donald J., Zhang, Kang, Weinreb, Robert N., Pericak-Vance, Margaret A., Small, Kerrin, Hammond, Christopher J., Aung, Tin, Liu, Yutao, Vithana, Eranga N., MacGregor, Stuart, Craig, Jamie E., Kraft, Peter, Howell, Gareth, Hauser, Michael A., Pasquale, Louis R., Haines, Jonathan L., Wiggs, Janey L.
Publicado 2016